Search Results - "Laureys, Steven"
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The neural correlate of (un)awareness: lessons from the vegetative state
Published in Trends in cognitive sciences (01-12-2005)“…Consciousness has two main components: wakefulness and awareness. The vegetative state is characterized by wakefulness without awareness. Recent functional…”
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Disorders of consciousness after acquired brain injury: the state of the science
Published in Nature reviews. Neurology (01-02-2014)“…Key Points Disorders of consciousness (DOC) arise from direct perturbations of neural systems that regulate arousal and awareness, and indirectly from…”
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Diagnostic precision of PET imaging and functional MRI in disorders of consciousness: a clinical validation study
Published in The Lancet (British edition) (09-08-2014)“…Summary Background Bedside clinical examinations can have high rates of misdiagnosis of unresponsive wakefulness syndrome (vegetative state) or minimally…”
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Neural correlates of consciousness in patients who have emerged from a minimally conscious state: a cross-sectional multimodal imaging study
Published in Lancet neurology (01-07-2016)“…Summary Background Between pathologically impaired consciousness and normal consciousness exists a scarcely researched transition zone, referred to as…”
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Measuring consciousness in severely damaged brains
Published in Annual review of neuroscience (01-01-2014)“…Significant advances have been made in the behavioral assessment and clinical management of disorders of consciousness (DOC). In addition, functional…”
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Complexity of Multi-Dimensional Spontaneous EEG Decreases during Propofol Induced General Anaesthesia
Published in PloS one (07-08-2015)“…Emerging neural theories of consciousness suggest a correlation between a specific type of neural dynamical complexity and the level of consciousness: When…”
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The spectral exponent of the resting EEG indexes the presence of consciousness during unresponsiveness induced by propofol, xenon, and ketamine
Published in NeuroImage (Orlando, Fla.) (01-04-2019)“…Despite the absence of responsiveness during anesthesia, conscious experience may persist. However, reliable, easily acquirable and interpretable…”
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Diagnostic accuracy of the vegetative and minimally conscious state: clinical consensus versus standardized neurobehavioral assessment
Published in BMC neurology (21-07-2009)“…Previously published studies have reported that up to 43% of patients with disorders of consciousness are erroneously assigned a diagnosis of vegetative state…”
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A theoretically based index of consciousness independent of sensory processing and behavior
Published in Science translational medicine (14-08-2013)“…One challenging aspect of the clinical assessment of brain-injured, unresponsive patients is the lack of an objective measure of consciousness that is…”
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Consciousness and Complexity during Unresponsiveness Induced by Propofol, Xenon, and Ketamine
Published in Current biology (07-12-2015)“…A common endpoint of general anesthetics is behavioral unresponsiveness [1], which is commonly associated with loss of consciousness. However, subjects can…”
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Stratification of unresponsive patients by an independently validated index of brain complexity
Published in Annals of neurology (01-11-2016)“…Objective Validating objective, brain‐based indices of consciousness in behaviorally unresponsive patients represents a challenge due to the impossibility of…”
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DMT Models the Near-Death Experience
Published in Frontiers in psychology (15-08-2018)“…Near-death experiences (NDEs) are complex subjective experiences, which have been previously associated with the psychedelic experience and more specifically…”
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13
Burnout syndrome in healthcare professionals who care for patients with prolonged disorders of consciousness: a cross-sectional survey
Published in BMC health services research (07-09-2020)“…Burnout is more common among healthcare professionals, that is an important problem of professional distress that can seriously affect healthcare…”
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14
Bedside detection of awareness in the vegetative state: a cohort study
Published in The Lancet (British edition) (17-12-2011)“…Summary Background Patients diagnosed as vegetative have periods of wakefulness, but seem to be unaware of themselves or their environment. Although functional…”
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15
Spasticity after stroke: Physiology, assessment and treatment
Published in Brain injury (01-09-2013)“…Abstract Background: Spasticity following a stroke occurs in about 30% of patients. The mechanisms underlying this disorder, however, are not well understood…”
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Willful Modulation of Brain Activity in Disorders of Consciousness
Published in The New England journal of medicine (18-02-2010)“…In this study involving 54 patients in a vegetative or minimally conscious state, the use of functional magnetic resonance imaging (MRI) to assess responses…”
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Perturbations in dynamical models of whole-brain activity dissociate between the level and stability of consciousness
Published in PLoS computational biology (27-07-2021)“…Consciousness transiently fades away during deep sleep, more stably under anesthesia, and sometimes permanently due to brain injury. The development of an…”
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The Minimal Energetic Requirement of Sustained Awareness after Brain Injury
Published in Current biology (06-06-2016)“…Differentiation of the minimally conscious state (MCS) and the unresponsive wakefulness syndrome (UWS) is a persistent clinical challenge [1]. Based on…”
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The misdiagnosis of prolonged disorders of consciousness by a clinical consensus compared with repeated coma-recovery scale-revised assessment
Published in BMC neurology (12-09-2020)“…Previous studies have shown that a single Coma-Recovery Scale-Revision (CRS-R) assessment can identify high rates of misdiagnosis by clinical consensus. The…”
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20
Recovery of cortical effective connectivity and recovery of consciousness in vegetative patients
Published in Brain (London, England : 1878) (01-04-2012)“…Patients surviving severe brain injury may regain consciousness without recovering their ability to understand, move and communicate. Recently,…”
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