Search Results - "Laurenti, Marcia Dalastra"
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Asymptomatic dogs are highly competent to transmit Leishmania (Leishmania) infantum chagasi to the natural vector
Published in Veterinary parasitology (23-09-2013)“…We evaluated the ability of dogs naturally infected with Leishmania (Leishmania) infantum chagasi to transfer the parasite to the vector and the factors…”
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Detection of Pintomyia fischeri (Diptera: Psychodidae) With Leishmania infantum (Trypanosomatida: Trypanosomatidae) Promastigotes in a Focus of Visceral Leishmaniasis in Brazil
Published in Journal of medical entomology (12-03-2021)“…Abstract Visceral leishmaniasis is spreading in Brazil where the main vector of its agent, Leishmania infantum Nicolle, 1908, is the Lutzomyia longipalpis…”
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Unveiling the Enigmatic nature of six neglected Amazonian Leishmania (Viannia) species using the hamster model: Virulence, Histopathology and prospection of LRV1
Published in PLoS neglected tropical diseases (01-08-2024)“…American tegumentary leishmaniasis (ATL) is highly endemic in the Amazon basin and occurs in all South American countries, except Chile and Uruguay. Most…”
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High Selectivity of 8-Hydroxyquinoline on Leishmania (Leishmania) and Leishmania (Viannia) Species Correlates with a Potent Therapeutic Activity In Vivo
Published in Pharmaceuticals (Basel, Switzerland) (07-05-2023)“…Leishmaniasis is a neglected disease caused by protozoa of the genus , which causes different clinical manifestations. Drugs currently used in the treatment…”
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Related Pentacyclic Triterpenes Have Immunomodulatory Activity in Chronic Experimental Visceral Leishmaniasis
Published in Journal of immunology research (2021)“…Leishmaniasis is a neglected tropical disease caused by the flagellated protozoa of the genus Leishmania that affects millions of people around the world…”
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Evaluation of Rhamnetin as an Inhibitor of the Pharmacological Effect of Secretory Phospholipase A2
Published in Molecules (Basel, Switzerland) (31-08-2017)“…Rhamnetin (Rhm), 3- -methylquercetin (3MQ), and Rhamnazin (Rhz) are methylated derivatives of quercetin commonly found in fruits and vegetables that possess…”
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Nanostructured Lipid Carriers as Robust Systems for Lupeol Delivery in the Treatment of Experimental Visceral Leishmaniasis
Published in Pharmaceuticals (Basel, Switzerland) (23-11-2023)“…Leishmaniasis is a neglected tropical disease that affects millions of people around the world. Available therapy causes severe side effects, has unacceptable…”
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Evaluation of systemic immunity in atypical cutaneous leishmaniasis caused by Leishmania (L.) infantum chagasi
Published in Parasite immunology (01-01-2022)“…In some central‐American countries, Leishmania (L.) infantum chagasi infection can cause non‐ulcerated or atypical cutaneous leishmaniasis (NUCL) in addition…”
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Leishmanicidal Activity and Ultrastructural Changes of Maslinic Acid Isolated from Hyptidendron canum
Published in Evidence-based complementary and alternative medicine (2021)“…The therapeutic arsenal for the treatment of leishmaniasis is limited and has serious obstacles, such as variable activity, high toxicity, and costs. To…”
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Detection of Leishmania infantum DNA in Pintomyia evansi and Lutzomyia longipalpis in Honduras
Published in Parasites & vectors (23-11-2020)“…Abstract Background The two most abundant sand fly species on the Honduran Pacific coast are Lutzomyia ( Lutzomyia ) longipalpis and Pintomyia ( Pifanomyia )…”
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Preclinical Assessment of Ursolic Acid Loaded into Nanostructured Lipid Carriers in Experimental Visceral Leishmaniasis
Published in Pharmaceutics (19-06-2021)“…Ursolic acid, a triterpene produced by plants, displayed leishmanicidal activity in vitro and in vivo; however, the low solubility of this triterpene limits…”
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Serological cross-reactivity of Trypanosoma cruzi, Ehrlichia canis, Toxoplasma gondii, Neospora caninum and Babesia canis to Leishmania infantum chagasi tests in dogs
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2014)“…The aim of this study was to evaluate the serological cross-reactivity between Leishmania sp. and other canine pathogens. Positive serum samples for Ehrlichia…”
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13
Repurposing Butenafine as An Oral Nanomedicine for Visceral Leishmaniasis
Published in Pharmaceutics (20-07-2019)“…Leishmaniasis is a neglected tropical disease affecting more than 12 million people worldwide, which in its visceral clinical form (VL) is characterised by the…”
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Therapeutic Activity of a Topical Formulation Containing 8-Hydroxyquinoline for Cutaneous Leishmaniasis
Published in Pharmaceutics (01-11-2023)“…Cutaneous leishmaniasis exhibits a wide spectrum of clinical manifestations; however, only a limited number of drugs are available and include Glucantime® and…”
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Ethnopharmacology Study of Plants from Atlantic Forest with Leishmanicidal Activity
Published in Evidence-based complementary and alternative medicine (01-01-2019)“…Leishmaniasis is an infectious disease caused by a protozoan belonging to Leishmania genus. Different clinical outcomes can be observed depending on the…”
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Ursolic Acid Potentializes Conventional Therapy in Experimental Leishmaniasis
Published in Pathogens (Basel) (20-10-2020)“…Ursolic acid (UA) is a triterpene with a broad array of pharmacological activities. In leishmaniasis, UA killed different species of parasites, and it was…”
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Serum Cytokine Responses over the Entire Clinical-Immunological Spectrum of Human Leishmania (L.) infantum chagasi Infection
Published in BioMed research international (01-01-2016)“…The clinical-immunological spectrum of human Leishmania (L.) infantum chagasi infection in Amazonian Brazil was recently reviewed based on clinical, DTH, and…”
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Exposure to Leishmania spp. infection and Lutzomyia spp. in individuals living in an area endemic for visceral leishmaniasis in Brazil
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2020)“…This study aimed to investigate human exposure to Leishmania spp. infection and sandflies in an area endemic for the disease. The presence of antibodies…”
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Evaluation of Regulatory Immune Response in Skin Lesions of Patients Affected by Nonulcerated or Atypical Cutaneous Leishmaniasis in Honduras, Central America
Published in Mediators of inflammation (01-01-2018)“…In Honduras, Leishmania (L.) infantum chagasi causes both visceral leishmaniasis (LV) and nonulcerated or atypical cutaneous leishmaniasis (NUCL). NUCL is…”
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Comparative Genomic Analyses of New and Old World Viscerotropic Leishmanine Parasites: Further Insights into the Origins of Visceral Leishmaniasis Agents
Published in Microorganisms (Basel) (21-12-2022)“…Visceral leishmaniasis (VL), also known as kala-azar, is an anthropozoonotic disease affecting human populations on five continents. Aetiologic agents belong…”
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