Search Results - "Laurenti, L."

Contour Method with Uncertainty Quantification: A Robust and Optimised Framework via Gaussian Process Regression by Tognan, A., Laurenti, L., Salvati, E.

“…Background Over the past 20 years, the Contour Method (CM) has been extensively implemented to evaluate residual stress at the macro scale, especially in…”
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Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia by Arruga, F, Gizdic, B, Serra, S, Vaisitti, T, Ciardullo, C, Coscia, M, Laurenti, L, D'Arena, G, Jaksic, O, Inghirami, G, Rossi, D, Gaidano, G, Deaglio, S

“…The purpose of this study was to compare the expression and function of NOTCH1 in chronic lymphocytic leukemia (CLL) patients harboring a wild-type (WT) or…”
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Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells by Gobessi, S, Laurenti, L, Longo, P G, Carsetti, L, Berno, V, Sica, S, Leone, G, Efremov, D G

“…The protein kinase Syk is a key mediator of proximal B-cell receptor (BCR) signaling. Following antigen stimulation, Syk is recruited to the BCR and becomes…”
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Effect of HLA mismatch on post-transplant infections in allogeneic hematopoietic stem cell transplantation with PTCy-based GvHD prophylaxis by Marra, J. D., Galli, E., Giammarco, S., Chiusolo, P., Metafuni, E., Sora, F., Laurenti, L., Innocenti, I., Autore, F., Limongiello, M. A., Fresa, A., Bacigalupo, A., Sica, S.

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NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL by DEL GIUDICE, Ilaria, ROSSI, Davide, GUARINI, Anna, GAIDANO, Gianluca, FOA, Robin, CHIARETTI, Sabina, MARINELLI, Marilisa, TAVOLARO, Simona, GABRIELLI, Sara, LAURENTI, Luca, MARASCA, Roberto, RASI, Silvia, FANGAZIO, Marco

“…Trisomy 12, the third most frequent chromosomal aberration in chronic lymphocytic leukemia (CLL), confers an intermediate prognosis. In our cohort of 104…”
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Ibrutinib‐associated palmo‐plantar fissures in a patient with Chronic Lymphocytic Leukaemia: a novel cutaneous adverse event by Sollena, P., Mannino, M., Laurenti, L., De Simone, C., Peris, K.

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First‐line treatment of Waldenström's macroglobulinemia in Italy: A multicenter real‐life study on 547 patients to evaluate the long‐term efficacy and tolerability of different chemoimmunotherapy strategies by Autore, Francesco, Tedeschi, A., Benevolo, G., Mattiello, V., Galli, E., Danesin, N., Rizzi, R., Olivieri, J., Cencini, E., Puccini, B., Ferrarini, I., Marino, D., Bullo, M., Rossini, B., Motta, M., Innocenti, I., Fresa, A., Stirparo, L., Petrilli, D., Pasquale, R., Musto, P., Scapinello, G., Noto, A., Peri, V., Zamprogna, G., Hohaus, S., Frustaci, A. M., Piazza, F., Ferrero, S., Laurenti, L.

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The miR-17 similar to 92 family regulates the response to Toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes by Bomben, R, Gobessi, S, Dal Bo, M, Volinia, S, Marconi, D, Tissino, E, Benedetti, D, Zucchetto, A, Rossi, D, Gaidano, G, Del Poeta, G, Laurenti, L, Efremov, D G, Gattei, V

“…Chronic lymphocytic leukemia (CLL) cells from clinically aggressive cases have a greater capacity to respond to external microenvironmental stimuli, including…”
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Diagnostic and prognostic role of PET/CT in patients with chronic lymphocytic leukemia and progressive disease by Mauro, F R, Chauvie, S, Paoloni, F, Biggi, A, Cimino, G, Rago, A, Gentile, M, Morabito, F, Coscia, M, Bellò, M, Sacchetti, G M, Rossi, D, Laurenti, L, Autore, F, Campanelli, M, Trastulli, F, Nicolai, E, Riminucci, M, Gaidano, G, Guarini, A, Gallamini, A, Foà, R

“…In order to evaluate the predictive value of positron emission tomography–computed tomography (PET/CT) in discriminating the presence of a Richter’s syndrome…”
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ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission by Peyvandi, Flora, Lavoretano, Silvia, Palla, Roberta, Feys, Hendrik B, Vanhoorelbeke, Karen, Battaglioli, Tullia, Valsecchi, Carla, Canciani, Maria Teresa, Fabris, Fabrizio, Zver, Samo, Reti, Marienn, Mikovic, Danijela, Karimi, Mehran, Giuffrida, Gaetano, Laurenti, Luca, Mannucci, Pier Mannuccio

“…1 Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, University of Milan, Department of Medicine and Medical Specialities, IRCCS Maggiore Hospital,…”
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P623: IBRUTINIB REGULATES MIR‐181A/B VIA C‐FOS IN CHRONIC LYMPHOCYTIC LEUKEMIA by Ramassone, A., Palmiero, F., Tomasso, A., Innocenti, I., Laurenti, L., Visone, R.

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Bendamustine in combination with Ofatumumab in relapsed or refractory chronic lymphocytic leukemia: a GIMEMA Multicenter Phase II Trial by Cortelezzi, A, Sciumè, M, Liberati, A M, Vincenti, D, Cuneo, A, Reda, G, Laurenti, L, Zaja, F, Marasca, R, Chiarenza, A, Gritti, G, Orsucci, L, Storti, S, Angelucci, E, Cascavilla, N, Gobbi, M, Mauro, F R, Morabito, F, Fabris, S, Piciocchi, A, Vignetti, M, Neri, A, Rossi, D, Giannarelli, D, Guarini, A, Foà, R

“…We conducted a phase II, noncomparative, open-label, multicenter GIMEMA (Gruppo Italiano Malattie EMatologiche dell'Adulto) study (CLL0809) to assess the…”
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The risk of thrombosis in patients with acute leukemia: occurrence of thrombosis at diagnosis and during treatment by DE STEFANO, V., SORÀ, F., ROSSI, E., CHIUSOLO, P., LAURENTI, L., FIANCHI, L., ZINI, G., PAGANO, L., SICA, S., LEONE, G.

“…Background: Thromboembolism can occur during acute leukemia, especially acute lymphoid leukemia (ALL) treated with l‐asparaginase. Yet, most reports are…”
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The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease by LONGO, P. G, LAURENTI, L, GOBESSI, S, PETLICKOVSKI, A, PELOSI, M, CHIUSOLO, P, SICA, S, LEONE, G, EFREMOV, D. G

“…Chronic lymphocytic leukemia (CLL) B-cells are hyporesponsive to many proliferative signals that induce activation of normal B-lymphocytes. However, a…”
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ZANUBRUTINIB (ZANU) VERSUS BENDAMUSTINE + RITUXIMAB (BR) IN PATIENTS (PTS) WITH TREATMENT‐NAïVE (TN) CLL/SLL: EXTENDED FOLLOW‐UP OF THE SEQUOIA STUDY by Shadman, M., Munir, T., Roback, T., Brown, J. R., Kahl, B. S., Ghia, P., Giannopoulos, K., Šimkovič, M., Österborg, A., Laurenti, L., Walker, P., Opat, S., Ciepluch, H., Greil, R., Hanna, M., Tani, M., Trněný, M., Brander, D., Flinn, I. W., Grosicki, S., Verner, E., Tedeschi, A., De Guibert, S., Tumyan, G., Laribi, K., García, J. A., Li, J., Tian, T., Ramakrishnan, V., Liu, Y., Szeto, A., Paik, J., Cohen, A., Tam, C. S., Jurczak, W.

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Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia by Veronese, A, Pepe, F, Chiacchia, J, Pagotto, S, Lanuti, P, Veschi, S, Di Marco, M, D'Argenio, A, Innocenti, I, Vannata, B, Autore, F, Marchisio, M, Wernicke, D, Verginelli, F, Leone, G, Rassenti, L Z, Kipps, T J, Mariani-Costantini, R, Laurenti, L, Croce, C M, Visone, R

“…Deregulation of the miR-15a/16-1 cluster has a key role in the pathogenesis of chronic lymphocytic leukemia (CLL), a clinically heterogeneous disease with…”
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PB1872: ANTIBODY RESPONSES AFTER COVID‐19 VACCINATION IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKAEMIA, EITHER TREATED OR NAÏVE. A MONOCENTRIC EXPERIENCE by Innocenti, I., Benintende, G., Stirparo, L., Tomasso, A., Mosca, A., Fresa, A., Galli, E., Autore, F., Laurenti, L.

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S135: CRISPR/CAS9 EDITING REVEALS DEPENDENCE OF HUMAN RICHTER SYNDROME AND MURINE CLL CELLS ON SIGNALS FROM B CELL RECEPTOR, CXCR4 RECEPTOR AND MACROPHAGES BUT NOT FROM TOLL‐LIKE RECEPTORS IN VIVO by Martines, C., Chakraborty, S., Guastafierro, V., Vujovikj, M., Vaisitti, T., Deaglio, S., Laurenti, L., Dimovski, A., Efremov, D.

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Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate by Chiusolo, P., Reddiconto, G., Casorelli, I., Laurenti, L., Sorà, F., Mele, L., Annino, L., Leone, G., Sica, S.

“…Background: Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, a common mutation of the gene encoding the enzyme that catalyzes reduction of…”
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PO-54 - Clinical and laboratory characterization of platelet dysfunction caused by ibrutinib treatment in patients with chronic lymphocytic leukemia by Alberelli, M.A, Innocenti, I, Sica, S, Laurenti, L, De Candia, E

“…Introduction Ibrutinib treatment in patients with chronic lymphatic leukemia (LLC) is associated with bleeding-related adverse events. About 50% of treated…”
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