Search Results - "Laurent, Sarah"

A systematic review of neurological symptoms and complications of COVID-19 by Chen, Xiangliang, Laurent, Sarah, Onur, Oezguer A., Kleineberg, Nina N., Fink, Gereon R., Schweitzer, Finja, Warnke, Clemens

“…Objective To study the frequency of neurological symptoms and complications in COVID-19 patients in a systematic review of the literature. Methods Relevant…”
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The legacy of structural racism: Associations between historic redlining, current mortgage lending, and health by Lynch, Emily E., Malcoe, Lorraine Halinka, Laurent, Sarah E., Richardson, Jason, Mitchell, Bruce C., Meier, Helen C.S.

“…Structural racism, which is embedded in past and present operations of the U.S. housing market, is a fundamental cause of racial health inequities. We…”
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Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein by Spadaro, Melania, Winklmeier, Stephan, Beltrán, Eduardo, Macrini, Caterina, Höftberger, Romana, Schuh, Elisabeth, Thaler, Franziska S., Gerdes, Lisa Ann, Laurent, Sarah, Gerhards, Ramona, Brändle, Simone, Dornmair, Klaus, Breithaupt, Constanze, Krumbholz, Markus, Moser, Markus, Krishnamoorthy, Gurumoorthy, Kamp, Frits, Jenne, Dieter, Hohlfeld, Reinhard, Kümpfel, Tania, Lassmann, Hans, Kawakami, Naoto, Meinl, Edgar

“…Objective Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) occur in a proportion of patients with inflammatory demyelinating diseases of the…”
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Immunological Aspects of Approved MS Therapeutics by Rommer, Paulus S, Milo, Ron, Han, May H, Satyanarayan, Sammita, Sellner, Johann, Hauer, Larissa, Illes, Zsolt, Warnke, Clemens, Laurent, Sarah, Weber, Martin S, Zhang, Yinan, Stuve, Olaf

“…Multiple sclerosis (MS) is the most common neurological immune-mediated disease leading to disability in young adults. The outcome of the disease is…”
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γ-secretase directly sheds the survival receptor BCMA from plasma cells by Laurent, Sarah A., Hoffmann, Franziska S., Kuhn, Peer-Hendrik, Cheng, Qingyu, Chu, Yuanyuan, Schmidt-Supprian, Marc, Hauck, Stefanie M., Schuh, Elisabeth, Krumbholz, Markus, Rübsamen, Heike, Wanngren, Johanna, Khademi, Mohsen, Olsson, Tomas, Alexander, Tobias, Hiepe, Falk, Pfister, Hans-Walter, Weber, Frank, Jenne, Dieter, Wekerle, Hartmut, Hohlfeld, Reinhard, Lichtenthaler, Stefan F., Meinl, Edgar

“…Survival of plasma cells is regulated by B-cell maturation antigen (BCMA), a membrane-bound receptor activated by its agonist ligands BAFF and APRIL. Here we…”
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B-Cell Maturation Antigen (BCMA) as a Biomarker and Potential Treatment Target in Systemic Lupus Erythematosus by Martin, Jonas, Cheng, Qingyu, Laurent, Sarah A, Thaler, Franziska S, Beenken, Anne Elisabeth, Meinl, Edgar, Krönke, Gerhard, Hiepe, Falk, Alexander, Tobias

“…The BAFF-APRIL system is crucial for the pathogenesis of systemic lupus erythematosus (SLE) by promoting B cell survival, differentiation and the maintenance…”
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The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity by Hoffmann, Franziska S, Kuhn, Peer-Hendrik, Laurent, Sarah A, Hauck, Stefanie M, Berer, Kerstin, Wendlinger, Simone A, Krumbholz, Markus, Khademi, Mohsen, Olsson, Tomas, Dreyling, Martin, Pfister, Hans-Walter, Alexander, Tobias, Hiepe, Falk, Kümpfel, Tania, Crawford, Howard C, Wekerle, Hartmut, Hohlfeld, Reinhard, Lichtenthaler, Stefan F, Meinl, Edgar

“…BAFF and a proliferation-inducing ligand (APRIL), which control B cell homeostasis, are therapeutic targets in autoimmune diseases. TACI-Fc (atacicept), a…”
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Soluble TACI and soluble BCMA as biomarkers in primary central nervous system lymphoma by Thaler, Franziska S, Laurent, Sarah A, Huber, Marion, Mulazzani, Matthias, Dreyling, Martin, Ködel, Uwe, Kümpfel, Tania, Straube, Andreas, Meinl, Edgar, von Baumgarten, Louisa

“…B-cell survival is regulated through interactions of B-cell-activating factor and a proliferation-inducing ligand with their receptors transmembrane activator…”
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Historic redlining in Columbus, Ohio associated with stroke prevalence by Wing, Jeffrey J., Lynch, Emily E., Laurent, Sarah E., Mitchell, Bruce, Richardson, Jason, Meier, Helen C.S.

“…Racial disparities exist in stroke and stroke outcomes. In an ecologic study, using the Home Owners’ Loan Corporation (HOLC) “redlining” scores, as indicator…”
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Eculizumab Use in Neuromyelitis Optica Spectrum Disorders: Routine Clinical Care Data From a European Cohort by Ringelstein, Marius, Asseyer, Susanna, Lindenblatt, Gero, Fischer, Katinka, Pul, Refik, Skuljec, Jelena, Revie, Lisa, Giglhuber, Katrin, Häußler, Vivien, Karenfort, Michael, Hellwig, Kerstin, Paul, Friedemann, Bellmann-Strobl, Judith, Otto, Carolin, Ruprecht, Klemens, Ziemssen, Tjalf, Emmer, Alexander, Rothhammer, Veit, Nickel, Florian T, Angstwurm, Klemens, Linker, Ralf, Laurent, Sarah A, Warnke, Clemens, Jarius, Sven, Korporal-Kuhnke, Mirjam, Wildemann, Brigitte, Wolff, Stephanie, Seipelt, Maria, Yalachkov, Yavor, Retzlaff, Nele, Zettl, Uwe K, Rommer, Paulus S, Kowarik, Markus C, Wickel, Jonathan, Geis, Christian, Hümmert, Martin W, Trebst, Corinna, Senel, Makbule, Gold, Ralf, Klotz, Luisa, Kleinschnitz, Christoph, Meuth, Sven G, Aktas, Orhan, Berthele, Achim, Ayzenberg, Ilya

“…Attack prevention is crucial in managing neuromyelitis optica spectrum disorders (NMOSDs). Eculizumab (ECU), an inhibitor of the terminal complement cascade,…”
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Histopathology and clinical course of MOG‐antibody‐associated encephalomyelitis by Spadaro, Melania, Gerdes, Lisa Ann, Mayer, Marie C., Ertl‐Wagner, Birgit, Laurent, Sarah, Krumbholz, Markus, Breithaupt, Constanze, Högen, Tobias, Straube, Andreas, Giese, Armin, Hohlfeld, Reinhard, Lassmann, Hans, Meinl, Edgar, Kümpfel, Tania

“…We present histological, MRI, and clinical features of an adult patient with relapsing encephalomyelitis and antibodies against myelin oligodendrocyte…”
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Measles IgG antibody index correlates with T2 lesion load on MRI in patients with early multiple sclerosis by Rosche, Berit, Laurent, Sarah, Conradi, Silja, Hofmann, Jörg, Ruprecht, Klemens, Harms, Lutz

“…B cells and humoral immune responses play an important role in the pathogenesis and diagnosis of multiple sclerosis (MS). A characteristic finding in patients…”
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Effect of Ocrelizumab on B- and T-Cell Receptor Repertoire Diversity in Patients With Relapsing Multiple Sclerosis From the Randomized Phase III OPERA Trial by Laurent, Sarah A, Strauli, Nicolas B, Eggers, Erica L, Wu, Hao, Michel, Brady, Demuth, Stanislas, Palanichamy, Arumugam, Wilson, Michael R, Sirota, Marina, Hernandez, Ryan D, Cree, Bruce Anthony Campbell, Herman, Ann E, von Büdingen, H-Christian

“…The B cell-depleting anti-CD20 antibody ocrelizumab (OCR) effectively reduces MS disease activity and slows disability progression. Given the role of B cells…”
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Cholinergic Antagonists and Behavioral Disturbances in Neurodegenerative Diseases by Mahmoudi, Rachid, Novella, Jean Luc, Laurent-Badr, Sarah, Boulahrouz, Sarah, Tran, David, Morrone, Isabella, Jaïdi, Yacine

“…Cholinergic antagonists interfere with synaptic transmission in the central nervous system and are involved in pathological processes in patients with…”
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Soluble TACI and soluble BCMA as biomarkers in primary central nervous system lymphoma by Thaler, Franziska S, Laurent, Sarah A, Huber, Marion, Mulazzani, Matthias, Dreyling, Martin, Ködel, Uwe, Kümpfel, Tania, Straube, Andreas, Meinl, Edgar, von Baumgarten, Louisa

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Soluble BCMA is shed from B cells by gamma-secretase, functions as APRIL-specific decoy and reflects intrathecal Ig-production in multiple sclerosis by Laurent, Sarah A, Hoffmann, Franziska, Kuhn, Peer-hendrik, Hauck, Stephanie M, Khademi, Mohsen, Olsson, Tomas, Pfister, Hans-walter, Weber, Frank, Hohlfeld, Reinhard, Lichtenthaler, Stefan F, Meinl, Edgar

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ADAM10 releases the immunoregulator soluble TACI — A novel biomarker for B-cell pathologies by Hoffmann, Franziska, Kuhn, Peer-Hendrik, Laurent, Sarah A, Hauck, Stefanie M, Berer, Kerstin, Krumbholz, Markus, Khademi, Mohsen, Olsson, Tomas, Dreyling, Martin, Pfister, Hans-Walter, Alexander, Tobias, Hiepe, Falk, Kümpfel, Tania, Crawford, Howard C, Wekerle, Hartmut, Hohlfeld, Reinhard, Lichtenthaler, Stefan F, Meinl, Edgar

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Age and the risks of high-efficacy disease modifying drugs in multiple sclerosis by Schweitzer, Finja, Laurent, Sarah, Fink, Gereon R, Barnett, Michael H, Reddel, Stephen, Hartung, Hans-Peter, Warnke, Clemens

“…A variety of high-efficacy disease-modifying therapies (DMTs) are available for the treatment of multiple sclerosis (MS). After evaluation and approval by…”
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Progressive Multifocal Leukoencephalopathy: Pathogenesis, Diagnostic Tools, and Potential Biomarkers of Response to Therapy by Schweitzer, Finja, Laurent, Sarah, Cortese, Irene, Fink, Gereon R., Silling, Steffi, Skripuletz, Thomas, Metz, Imke, Wattjes, Mike P., Warnke, Clemens

“…JC polyomavirus (JCV) establishes an asymptomatic latent and/or persistent infection in most of the adult population. However, in immunocompromised…”
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Chimeric antigen receptor T-cell therapy for autoimmune diseases of the central nervous system: a systematic literature review by Konitsioti, Agni M., Prüss, Harald, Laurent, Sarah, Fink, Gereon R., Heesen, Christoph, Warnke, Clemens

“…Importance B-cell-targeting monoclonal antibodies have demonstrated safety and efficacy in multiple sclerosis or anti-aquaporin-4 IgG positive neuromyelitis…”
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