Search Results - "Laurent, Brehon C."

Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair by Chai, Bob, Huang, Jian, Cairns, Bradley R, Laurent, Brehon C

“…The failure of cells to repair damaged DNA can result in genomic instability and cancer. To efficiently repair chromosomal DNA lesions, the repair machinery…”
Get full text

The Yeast RSC Chromatin-Remodeling Complex Is Required for Kinetochore Function in Chromosome Segregation by Hsu, Jing-mei, Huang, Jian, Meluh, Pamela B., Laurent, Brehon C.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

ATP-Dependent Chromatin-Remodeling Complexes in DNA Double-Strand Break Repair: Remodeling, Pairing and (Re)pairing by Huang, Jian, Liang, Bing, Qiu, Jiajing, Laurent, Brehon C.

“…The genomic integrity of a eukaryotic cell is challenged by over 10,000 chromosomal lesions perday. Therefore the cell has evolved efficient mechanisms to…”
Get full text

The RSC Nucleosome-Remodeling Complex Is Required for Cohesin's Association With Chromosome Arms by Huang, Jian, Hsu, Jing-mei, Laurent, Brehon C

“…The fidelity of chromosome segregation requires that the cohesin protein complex bind together newly replicated sister chromatids both at centromeres and at…”
Get full text

RSC Functions as an Early Double-Strand-Break Sensor in the Cell's Response to DNA Damage by Liang, Bing, Qiu, Jiajing, Ratnakumar, Kajan, Laurent, Brehon C.

“…The detection of a DNA double-strand break (DSB) is necessary to initiate DSB repair. Several proteins, including the MRX/N complex, Tel1/ATM (ataxia…”
Get full text

Yeast RSC Function Is Required for Organization of the Cellular Cytoskeleton via an Alternative PKC1 Pathway by Chai, Bob, Hsu, Jing-mei, Du, Jian, Laurent, Brehon C

“…RSC is a 15-protein ATP-dependent chromatin-remodeling complex related to Snf-Swi, the prototypical ATP-dependent nucleosome remodeler in budding yeast…”
Get full text

A Role for the RSC Chromatin Remodeler in Regulating Cohesion of Sister Chromatid Arms by Huang, Jian, Laurent, Brehon C.

“…The precise segregation of chromosomes is critical for the proliferation and development of living organisms. Defects in this process can result in…”
Get full text

Roles of SWI/SNF and HATs throughout the dynamic transcription of a yeast glucose-repressible gene by Geng, Fuqiang, Laurent, Brehon C

“…Eucaryotic gene expression requires chromatin‐remodeling activities. We show by time‐course studies that transcriptional induction of the yeast…”
Get full text

The SNF/SWI family of global transcriptional activators by Carlson, M, Laurent, B C

“…The yeast SNF/SWI proteins have a global role in transcriptional activation. This set of five proteins assists many gene-specific activators, most likely by…”
Get more information

Chromatin remodeling and repair of DNA double-strand breaks by Wong, Lai-Yee, Recht, Judith, Laurent, Brehon C

“…Eukaryotic cells have developed conserved mechanisms to efficiently sense and repair DNA damage that results from constant chromosomal lesions. DNA repair has…”
Get full text

nucleosome remodeling complex, Snf/Swi, is required for the maintenance of transcription in vivo and is partially redundant with the histone acetyltransferase, Gcn5 by Sudarsanam, P, Cao, Y, Wu, L, Laurent, B.C, Winston, F

“…Snf/Swi, a nucleosome remodeling complex, is important for overcoming nucleosome‐mediated repression of transcription in Saccharomyces cerevisiae. We have…”
Get full text

Essential Roles of Snf5p in Snf-Swi Chromatin Remodeling In Vivo by Geng, Fuqiang, Cao, Yixue, Laurent, Brehon C.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast by Cairns, B.R, Kim, Y.J, Sayre, M.H, Laurent, B.C, Kornberg, R.D

“…A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNFS, and SNF6 genes and four additional polypeptides has been purified from extracts of…”
Get full text

Sth1p, a Saccharomyces cerevisiae Snf2p/Swi2p Homolog, Is an Essential ATPase in RSC and Differs From Snf/Swi in Its Interactions With Histones and Chromatin-Associated Proteins by Du, Jian, Nasir, Irem, Benton, Benjamin K, Kladde, Michael P, Laurent, Brehon C

“…The essential Sth1p is the protein most closely related to the conserved Snf2p/Swi2p in Saccharomyces cerevisiae. Sth1p purified from yeast has a…”
Get full text

Sfh1p, a component of a novel chromatin-remodeling complex, is required for cell cycle progression by Cao, Yixue, Cairns, Bradley R., Kornberg, Roger D., Laurent, Brehon C.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

A Role for the RSC chromatin remodeler in regulating cohesion of sister chromatid arms by Huang, Jian, Laurent, Brehon C

“…The precise segregation of chromosomes is critical for the proliferation and development of living organisms. Defects in this process can result in…”
Get full text

The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation by LAURENT, B. C, TREICH, I, CARLSON, M

“…The yeast SNF2 (SWI2) protein functions with SNF5, SNF6, SWI1, and SWI3 in the transcriptional activation of many differently regulated genes. These proteins…”
Get full text

The RSC Nucleosome-Remodeling Complex Is Required for Cohesin's Association with Chromosome Arms by Huang, Jian, Hsu, Jing-mei, Laurent, Brehon C

Get full text

An essential Saccharomyces cerevisiae gene homologous to SNF2 encodes a helicase-related protein in a new family by Laurent, B C, Yang, X, Carlson, M

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Functional Interdependence of the Yeast SNF2, SNF5, and SNF6 Proteins in Transcriptional Activation by Laurent, Brehon C., Treitel, Michelle A., Carlson, Marian

“…The SNF2, SNF5, and SNF6 genes of Saccharomyces cerevisiae are required for expression of a variety of differently regulated genes. Previous evidence…”
Get full text