Search Results - "Laurence, Maggiorella"

Oncogenic K-Ras Signals through Epidermal Growth Factor Receptor and Wild-Type H-Ras to Promote Radiation Survival in Pancreatic and Colorectal Carcinoma Cells by Cengel, Keith A., Voong, K. Rahn, Chandrasekaran, Sanjay, Maggiorella, Laurence, Brunner, Thomas B., Stanbridge, Eric, Kao, Gary D., McKenna, W. Gillies, Bernhard, Eric J.

“…Pancreatic and colorectal carcinomas frequently express oncogenic/mutant K-Ras that contributes to both tumorigenesis and clinically observed resistance to…”
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Angiogenesis and tumor growth inhibition by a matrix metalloproteinase inhibitor targeting radiation-induced invasion by Kaliski, Alexandre, Maggiorella, Laurence, Cengel, Keith A, Mathe, Denis, Rouffiac, Valerie, Opolon, Paule, Lassau, Nathalie, Bourhis, Jean, Deutsch, Eric

“…In this study, we have evaluated the interactions between ionizing radiation and a matrix metalloproteinase (MMP) inhibitor. Using Matrigel invasion assays, we…”
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Antiviral agent Cidofovir restores p53 function and enhances the radiosensitivity in HPV-associated cancers by ABDULKARIM, Bassam, SABRI, Siham, DEUTSCH, Eric, CHAGRAOUI, Heddia, MAGGIORELLA, Laurence, THIERRY, Jerome, ESCHWEGE, Francois, VAINCHENKER, William, CHOUAÏB, Salem, BOURHIS, Jean

“…High-risk human papillomaviruses (HPVs) have been associated to the development of cervical and some other human cancers. Most of them express E6 and E7…”
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Combined Radiation Sensitizing and Anti-angiogenic Effects of Ionizing Radiation and the Protease Inhibitor Ritonavir in a Head and Neck Carcinoma Model by Maggiorella, Laurence, Wen, Bixiu, Frascogna, Valerie, Opolon, Paule, Bourhis, Jean, Deutsch, Eric

“…Ritonavir, a protease inhibitor, has been successfully applied in the treatment of HIV infection. Reports of dramatic improvement of AIDS-related cancers, such…”
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Nanoscale radiotherapy with hafnium oxide nanoparticles by Maggiorella, Laurence, Barouch, Gilles, Devaux, Corinne, Pottier, Agnès, Deutsch, Eric, Bourhis, Jean, Borghi, Elsa, Levy, Laurent

“…There is considerable interest in approaches that could improve the therapeutic window of radiotherapy. In this study, hafnium oxide nanoparticles were…”
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The Olivacine S16020 Enhances the Antitumor Effect of Ionizing Radiation without Increasing Radio-induced Mucositis by MAGGIORELLA, Laurence, FRASCOGNA, Valérie, POULLAIN, Marie-Gwenaëlle, BERLION, Maryse, LUCAS, Catherine, RAZY, Setha Douc, ESCHWEGE, Francois, BOURHIS, Jean

“…The combination of a novel topoisomerase II inhibitor, S16020, and ionizing radiation (IR) was investigated with the aim of assessing normal tissue tolerance…”
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A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans by Chansel-Da Cruz, Marie, Hohl, Marcel, Ceppi, Ilaria, Kermasson, Laëtitia, Maggiorella, Laurence, Modesti, Mauro, de Villartay, Jean-Pierre, Ileri, Talia, Cejka, Petr, Petrini, John H.J., Revy, Patrick

“…The MRE11-RAD50-NBS1 complex plays a central role in response to DNA double-strand breaks. Here, we identify a patient with bone marrow failure and…”
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A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans by Modesti, Mauro, Chansel-da Cruz, Marie, Hohl, Marcel, Ceppi, Ilaria, Kermasson, Laëtitia, Maggiorella, Laurence, de Villartay, Jean-Pierre, Ileri, Talia, Cejka, Petr, Petrini, John H.J., Revy, Patrick

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Abstract 2665: NBTXR3 hafnium oxide nanoparticle activated by ionizing radiation demonstrates marked radio-enhancement and antitumor effect via high energy deposit in human soft tissue sarcoma by Laurence, Maggiorella, Darmon, Audrey, Vivet, Sonia, Polrot, Mélanie, Zhang, Ping, Deutsch, Eric, Bourhis, Jean, Pottier, Agnès, Borghi, Elsa, Levy, Laurent

“…Abstract Local and systemic control of Soft Tissue Sarcoma (STS) remains a clinical challenge. Radiation therapy is part of the standard of care of STS. The…”
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BCR-ABL down-regulates the DNA repair protein DNA-PKcs by Deutsch, Eric, Dugray, Aymeric, AbdulKarim, Bassam, Marangoni, Elisabetta, Maggiorella, Laurence, Vaganay, Sabine, M'Kacher, Radia, Rasy, Setha Douc, Eschwege, François, Vainchenker, William, Turhan, Ali G., Bourhis, Jean

“…This study demonstrates in both stable and inducible BCR-ABL–expressing hematopoietic cells a down-regulation of the major mammalian DNA repair protein…”
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Environmental, genetic, and molecular features of prostate cancer by Deutsch, Eric, Maggiorella, Laurence, Eschwege, Pascal, Bourhis, Jean, Soria, Jean Charles, Abdulkarim, Bassam

“…Prostate cancer is the sixth most common cancer in the world and the third leading cause of cancer in men. The increase in the understanding of prostate…”
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Enhancement of radiation response by roscovitine in human breast carcinoma in vitro and in vivo by MAGGIORELLA, Laurence, DEUTSCH, Eric, FRASCOGNA, Valérie, CHAVAUDRA, Nicole, JEANSON, Laurence, MILLIAT, Fabien, ESCHWEGE, Francois, BOURHIS, Jean

“…Frequent deregulation of cyclin-dependent kinase (CDK) activation associated with loss of cell cycle control was found in most of human cancers. A recent…”
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Oncogenic K-Ras Signals through Epidermal Growth Factor Receptor and Wild-Type H-Ras to Promote Radiation Survival in Pancreatic and Colorectal Carcinoma Cells1 by Cengel, Keith A., Voong, K. Rahn, Chandrasekaran, Sanjay, Maggiorella, Laurence, Brunner, Thomas B., Stanbridge, Eric, Kao, Gary D., McKenna, W. Gillies, Bernhard, Eric J.

“…Pancreatic and colorectal carcinomas frequently express oncogenic/mutant K-Ras that contributes to both tumorigenesis and clinically observed resistance to…”
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