Search Results - "Laura Markham"
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Direct CRISPR spacer acquisition from RNA by a natural reverse transcriptase–Cas1 fusion protein
Published in Science (American Association for the Advancement of Science) (26-02-2016)“…CRISPR systems mediate adaptive immunity in diverse prokaryotes. CRISPR-associated Cas1 and Cas2 proteins have been shown to enable adaptation to new threats…”
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A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition
Published in Molecular cell (15-11-2018)“…Prokaryotic CRISPR-Cas systems provide adaptive immunity by integrating portions of foreign nucleic acids (spacers) into genomic CRISPR arrays. Cas6 proteins…”
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Validity and repeatability of cardiopulmonary exercise testing in interstitial lung disease
Published in BMC pulmonary medicine (22-12-2022)“…Cardiopulmonary exercise testing (CPET), and its primary outcome of peak oxygen uptake (VO ), are acknowledged as biomarkers in the diagnostic and prognostic…”
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Feasibility of cardiopulmonary exercise testing in interstitial lung disease: the PETFIB study
Published in BMJ open respiratory research (29-04-2021)“…IntroductionCardiopulmonary exercise testing (CPET) provides a series of biomarkers, such as peak oxygen uptake, which could assess the development of disease…”
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Feeding and eating disorders in childhood
Published in The International journal of eating disorders (01-03-2010)“…OBJECTIVE:: To review the literature related to the current DSM-IV-TR diagnostic criteria for feeding disorder of infancy or early childhood; pica; rumination…”
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Loss of miRNAs during Processing and Storage of Cow’s (Bos taurus) Milk
Published in Journal of agricultural and food chemistry (21-01-2015)“…MicroRNAs (miRs, miRNAs) play central roles in gene regulation. Previously, we reported that miRNAs from pasteurized, store-bought bovine milk have biological…”
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Mechanisms used for cDNA synthesis and site-specific integration of RNA into DNA genomes by a reverse transcriptase-Cas1 fusion protein
Published in Science advances (12-04-2024)“…Reverse transcriptase-Cas1 (RT-Cas1) fusion proteins found in some CRISPR systems enable spacer acquisition from both RNA and DNA, but the mechanism of RNA…”
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Resonance Raman spectroscopy as a test of ab initio methods for the computation of molecular potential energy surfaces
Published in Journal of Raman spectroscopy (01-06-1998)“…The use of ab initio quantum chemical methods to aid in the interpretation of resonance Raman spectra is illustrated with examples where the resonant…”
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Ab Initio Analysis of the Effects of Aqueous Solvation on the Resonance Raman Intensities of N-Methylacetamide
Published in Journal of physical chemistry (1952) (15-02-1996)“…The resonance Raman spectrum of the simple peptide N-methylacetamide (NMA) is very different in the vapor phase than when dissolved in aqueous solution. The…”
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The clinical presentation of avoidant restrictive food intake disorder in children and adolescents is largely independent of sex, autism spectrum disorder and anxiety traits
Published in EClinicalMedicine (01-09-2023)“…BackgroundAvoidant restrictive food intake disorder (ARFID) is a new eating disorder with a heterogeneous clinical presentation. It is unclear which patient…”
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The clinical presentation of avoidant restrictive food intake disorder in children and adolescents is largely independent of sex, autism spectrum disorder and anxiety traitsResearch in context
Published in EClinicalMedicine (01-09-2023)“…Background: Avoidant restrictive food intake disorder (ARFID) is a new eating disorder with a heterogeneous clinical presentation. It is unclear which patient…”
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Attitudes and Beliefs of Raw Milk Consumers in Northern Colorado
Published in Journal of hunger & environmental nutrition (02-10-2014)“…By exploring the attitudes and beliefs of northern Colorado raw cow milk consumers, this study seeks to improve understanding of factors motivating raw milk…”
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Resonance Raman studies of imidazole, imidazolium, and their derivatives: the effect of deuterium substitution
Published in Journal of physical chemistry (1952) (01-10-1993)“…Resonance Raman spectra of imidazole, imidazolium cation, 4-methylimidazole, histidine, and their cations are presented for the proto and N-deutero forms…”
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Exploring men's accounts of understanding and seeking help for problems with eating
Published 01-01-2013“…Objective: The silence around ‘eating disorders’ in males is reflected in a dearth of literature on prevalence, aetiology, treatment and outcome (Morgan,…”
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Dissertation -
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Resonance Raman spectroscopy as a test ofab initio methods for the computation of molecular potential energy surfaces
Published in Journal of Raman spectroscopy (01-06-1998)Get full text
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16
Dopamine Transporter Site-Directed Mutations Differentially Alter Substrate Transport and Cocaine Binding
Published in Proceedings of the National Academy of Sciences - PNAS (15-08-1992)“…Polar amino acids lying within three hydrophobic regions of the dopamine transporter (DAT) are analogous to those important for ligand recognition by…”
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The WISE group: Connecting activism, teaching, and research
Published in Journal of research in science teaching (01-04-1998)Get full text
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Mothers' mental representations of their relationships with their toddlers: A link to working models of their parents
Published 01-01-1998“…The purpose of this study was to examine the connection between mothers' mental representations of their childhood relationships with their own parents and…”
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Dissertation -
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THE CROW WHISPERER
Published in Harper's (New York, N.Y.) (01-04-2021)Get full text
Magazine Article -
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Response To Guest Editorial. The WISE Group: Connecting Activism, Teaching, and Research
Published in Journal of research in science teaching (01-04-1998)“…The WISE Group is a group of women who have been exploring feminism and relationships among teaching, research, and activist goals. The Call to Action…”
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Journal Article