Search Results - "Laura Markham"

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  1. 1

    Direct CRISPR spacer acquisition from RNA by a natural reverse transcriptase–Cas1 fusion protein by Silas, Sukrit, Mohr, Georg, Sidote, David J., Markham, Laura M., Sanchez-Amat, Antonio, Bhaya, Devaki, Lambowitz, Alan M., Fire, Andrew Z.

    “…CRISPR systems mediate adaptive immunity in diverse prokaryotes. CRISPR-associated Cas1 and Cas2 proteins have been shown to enable adaptation to new threats…”
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    Journal Article
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    A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition by Mohr, Georg, Silas, Sukrit, Stamos, Jennifer L., Makarova, Kira S., Markham, Laura M., Yao, Jun, Lucas-Elío, Patricia, Sanchez-Amat, Antonio, Fire, Andrew Z., Koonin, Eugene V., Lambowitz, Alan M.

    Published in Molecular cell (15-11-2018)
    “…Prokaryotic CRISPR-Cas systems provide adaptive immunity by integrating portions of foreign nucleic acids (spacers) into genomic CRISPR arrays. Cas6 proteins…”
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    Journal Article
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    Validity and repeatability of cardiopulmonary exercise testing in interstitial lung disease by Tomlinson, Owen W, Markham, Laura, Wollerton, Rebecca L, Knight, Bridget A, Duckworth, Anna, Gibbons, Michael A, Scotton, Chris J, Williams, Craig A

    Published in BMC pulmonary medicine (22-12-2022)
    “…Cardiopulmonary exercise testing (CPET), and its primary outcome of peak oxygen uptake (VO ), are acknowledged as biomarkers in the diagnostic and prognostic…”
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    Journal Article
  4. 4

    Feasibility of cardiopulmonary exercise testing in interstitial lung disease: the PETFIB study by Tomlinson, Owen, Duckworth, Anna, Markham, Laura, Wollerton, Rebecca, Knight, Bridget, Spiers, Alexander, Gibbons, Michael, Williams, Craig, Scotton, Chris

    Published in BMJ open respiratory research (29-04-2021)
    “…IntroductionCardiopulmonary exercise testing (CPET) provides a series of biomarkers, such as peak oxygen uptake, which could assess the development of disease…”
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    Journal Article
  5. 5

    Feeding and eating disorders in childhood by Bryant-Waugh, Rachel, Markham, Laura, Kreipe, Richard E, Walsh, B. Timothy

    “…OBJECTIVE:: To review the literature related to the current DSM-IV-TR diagnostic criteria for feeding disorder of infancy or early childhood; pica; rumination…”
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    Journal Article
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    Loss of miRNAs during Processing and Storage of Cow’s (Bos taurus) Milk by Howard, Katherine M, Jati Kusuma, Rio, Baier, Scott R, Friemel, Taylor, Markham, Laura, Vanamala, Jairam, Zempleni, Janos

    Published in Journal of agricultural and food chemistry (21-01-2015)
    “…MicroRNAs (miRs, miRNAs) play central roles in gene regulation. Previously, we reported that miRNAs from pasteurized, store-bought bovine milk have biological…”
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    Journal Article
  7. 7

    Mechanisms used for cDNA synthesis and site-specific integration of RNA into DNA genomes by a reverse transcriptase-Cas1 fusion protein by Mohr, Georg, Yao, Jun, Park, Seung Kuk, Markham, Laura, Lambowitz, Alan M

    Published in Science advances (12-04-2024)
    “…Reverse transcriptase-Cas1 (RT-Cas1) fusion proteins found in some CRISPR systems enable spacer acquisition from both RNA and DNA, but the mechanism of RNA…”
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    Journal Article
  8. 8

    Resonance Raman spectroscopy as a test of ab initio methods for the computation of molecular potential energy surfaces by Hudson, Bruce S., Markham, Laura M.

    Published in Journal of Raman spectroscopy (01-06-1998)
    “…The use of ab initio quantum chemical methods to aid in the interpretation of resonance Raman spectra is illustrated with examples where the resonant…”
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    Journal Article
  9. 9

    Ab Initio Analysis of the Effects of Aqueous Solvation on the Resonance Raman Intensities of N-Methylacetamide by Markham, Laura M, Hudson, Bruce S

    Published in Journal of physical chemistry (1952) (15-02-1996)
    “…The resonance Raman spectrum of the simple peptide N-methylacetamide (NMA) is very different in the vapor phase than when dissolved in aqueous solution. The…”
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    Journal Article
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    Attitudes and Beliefs of Raw Milk Consumers in Northern Colorado by Markham, Laura, Auld, Garry, Bunning, Marisa, Thilmany, Dawn

    “…By exploring the attitudes and beliefs of northern Colorado raw cow milk consumers, this study seeks to improve understanding of factors motivating raw milk…”
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    Journal Article
  13. 13

    Resonance Raman studies of imidazole, imidazolium, and their derivatives: the effect of deuterium substitution by Markham, Laura M, Mayne, Leland C, Hudson, Bruce S, Zgierski, Marek Z

    Published in Journal of physical chemistry (1952) (01-10-1993)
    “…Resonance Raman spectra of imidazole, imidazolium cation, 4-methylimidazole, histidine, and their cations are presented for the proto and N-deutero forms…”
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    Journal Article
  14. 14

    Exploring men's accounts of understanding and seeking help for problems with eating by Markham, Laura

    Published 01-01-2013
    “…Objective: The silence around ‘eating disorders’ in males is reflected in a dearth of literature on prevalence, aetiology, treatment and outcome (Morgan,…”
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    Dissertation
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    Dopamine Transporter Site-Directed Mutations Differentially Alter Substrate Transport and Cocaine Binding by Kitayama, Shigeo, Shimada, Shoichi, Xu, Hongxia, Markham, Laura, Donovan, David M., Uhl, George R.

    “…Polar amino acids lying within three hydrophobic regions of the dopamine transporter (DAT) are analogous to those important for ligand recognition by…”
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    Journal Article
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    Mothers' mental representations of their relationships with their toddlers: A link to working models of their parents by Markham, Laura Jean

    Published 01-01-1998
    “…The purpose of this study was to examine the connection between mothers' mental representations of their childhood relationships with their own parents and…”
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    Dissertation
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    Response To Guest Editorial. The WISE Group: Connecting Activism, Teaching, and Research by Cavazos, Lynnette, Hazelwood, Constanza Chiappe, Howes, Elaine V, Kurth, Lori, Lane, Paula, Markham, Laura, Richmond, Gail, Roth, Kathleen J

    Published in Journal of research in science teaching (01-04-1998)
    “…The WISE Group is a group of women who have been exploring feminism and relationships among teaching, research, and activist goals. The Call to Action…”
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    Journal Article