Search Results - "Laura García Expósito"

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres by Barroso-González, Jonathan, García-Expósito, Laura, Hoang, Song My, Lynskey, Michelle L., Roncaioli, Justin L., Ghosh, Arundhati, Wallace, Callen T., de Vitis, Marco, Modesti, Mauro, Bernstein, Kara A., Sarkar, Saumendra N., Watkins, Simon C., O’Sullivan, Roderick J.

“…Alternative lengthening of telomeres (ALT) is a homology-directed repair (HDR) mechanism of telomere elongation that controls proliferation in aggressive…”
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Moesin Regulates the Trafficking of Nascent Clathrin-coated Vesicles by Barroso-González, Jonathan, Machado, José-David, García-Expósito, Laura, Valenzuela-Fernández, Agustín

“…Clathrin-coated vesicles are responsible for the trafficking of several internalized biological cargos. We have observed that the endogenous F-actin-linker…”
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RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA by Kaminski, Nicole, Wondisford, Anne R., Kwon, Youngho, Lynskey, Michelle Lee, Bhargava, Ragini, Barroso-González, Jonathan, García-Expósito, Laura, He, Boxue, Xu, Meng, Mellacheruvu, Dattatreya, Watkins, Simon C., Modesti, Mauro, Miller, Kyle M., Nesvizhskii, Alexey I., Zhang, Huaiying, Sung, Patrick, O’Sullivan, Roderick J.

“…Alternative lengthening of telomeres (ALT) is a homology-directed repair (HDR) mechanism of telomere elongation that controls proliferation in subsets of…”
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Regulation of ALT-associated homology-directed repair by polyADP-ribosylation by Hoang, Song My, Kaminski, Nicole, Bhargava, Ragini, Barroso-González, Jonathan, Lynskey, Michelle L., García-Expósito, Laura, Roncaioli, Justin L., Wondisford, Anne R., Wallace, Callen T., Watkins, Simon C., James, Dominic I., Waddell, Ian D., Ogilvie, Donald, Smith, Kate M., da Veiga Leprevost, Felipe, Mellacharevu, Dattatreya, Nesvizhskii, Alexey I., Li, Jianfeng, Ray-Gallet, Dominique, Sobol, Robert W., Almouzni, Genevieve, O’Sullivan, Roderick J.

“…The synthesis of poly(ADP-ribose) (PAR) reconfigures the local chromatin environment and recruits DNA-repair complexes to damaged chromatin. PAR degradation by…”
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Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair by Barroso-González, Jonathan, García-Expósito, Laura, Galaviz, Pablo, Lynskey, Michelle Lee, Allen, Joshua A.M., Hoang, SongMy, Watkins, Simon C., Pickett, Hilda A., O’Sullivan, Roderick J.

“…Alternative lengthening of telomeres (ALT) is a telomere-elongation mechanism observed in ∼15% of cancer subtypes. Current models indicate that ALT is mediated…”
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RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres by Barroso-González, Jonathan, García-Expósito, Laura, Hoang, Song My, Lynskey, Michelle L., Roncaioli, Justin L., Ghosh, Arundhati, Wallace, Callen T., Modesti, Mauro, Bernstein, Kara A., Sarkar, Saumendra N., Watkins, Simon C., O’Sullivan, Roderick J.

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RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres by Barroso-González, Jonathan, García-Expósito, Laura, Hoang, Song My, Lynskey, Michelle L., Roncaioli, Justin L., Ghosh, Arundhati, Wallace, Callen T., de Vitis, Marco, Modesti, Mauro, Bernstein, Kara A., Sarkar, Saumendra N., Watkins, Simon C., O’Sullivan, Roderick J.

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The HDAC6/APOBEC3G complex regulates HIV-1 infectiveness by inducing Vif autophagic degradation by Valera, María-Soledad, de Armas-Rillo, Laura, Barroso-González, Jonathan, Ziglio, Serena, Batisse, Julien, Dubois, Noé, Marrero-Hernández, Sara, Borel, Sophie, García-Expósito, Laura, Biard-Piechaczyk, Martine, Paillart, Jean-Christophe, Valenzuela-Fernández, Agustín

“…Human immunodeficiency virus type 1 (HIV-1) has evolved a complex strategy to overcome the immune barriers it encounters throughout an organism thanks to its…”
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HIV-1 requires Arf6-mediated membrane dynamics to efficiently enter and infect T lymphocytes by García-Expósito, Laura, Barroso-González, Jonathan, Puigdomènech, Isabel, Machado, José-David, Blanco, Julià, Valenzuela-Fernández, Agustín

“…As the initial barrier to viral entry, the plasma membrane along with the membrane trafficking machinery and cytoskeleton are of fundamental importance in the…”
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Gelsolin activity controls efficient early HIV-1 infection by García-Expósito, Laura, Ziglio, Serena, Barroso-González, Jonathan, de Armas-Rillo, Laura, Valera, María-Soledad, Zipeto, Donato, Machado, José-David, Valenzuela-Fernández, Agustín

“…HIV-1 entry into target lymphocytes requires the activity of actin adaptors that stabilize and reorganize cortical F-actin, like moesin and filamin-A. These…”
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The Lupane-type Triterpene 30-Oxo-calenduladiol Is a CCR5 Antagonist with Anti-HIV-1 and Anti-chemotactic Activities by Barroso-González, Jonathan, El Jaber-Vazdekis, Nabil, García-Expósito, Laura, Machado, José-David, Zárate, Rafael, Ravelo, Ángel G., Estévez-Braun, Ana, Valenzuela-Fernández, Agustín

“…The existence of drug-resistant human immunodeficiency virus (HIV) viruses in patients receiving antiretroviral treatment urgently requires the…”
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Viral infection: Moving through complex and dynamic cell-membrane structures by Barroso-González, Jonathan, García-Expósito, Laura, Puigdomènech, Isabel, de Armas-Rillo, Laura, Machado, José-David, Blanco, Julià, Valenzuela-Fernández, Agustín

“…Viruses have developed different survival strategies in host cells by crossing cell-membrane compartments, during different steps of their viral life cycle. In…”
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TZAP‐ing telomeres down to size by Garcia‐Exposito, Laura, O'Sullivan, Roderick J

“…The phenomenon of gradual telomere shortening has become a paradigm for how we understand the biology of aging and cancer. Cell proliferation is accompanied by…”
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Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres by Garcia-Exposito, Laura, Bournique, Elodie, Bergoglio, Valérie, Bose, Arindam, Barroso-Gonzalez, Jonathan, Zhang, Sufang, Roncaioli, Justin L., Lee, Marietta, Wallace, Callen T., Watkins, Simon C., Opresko, Patricia L., Hoffmann, Jean-Sébastien, O’Sullivan, Roderick J.

“…Cancer cells rely on the activation of telomerase or the alternative lengthening of telomeres (ALT) pathways for telomere maintenance and survival. ALT…”
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Methodology for the Study of the Air Dispersion of the Industrial Contaminants Taking into Account the Orography by María José Suárez López, Laura García Expósito, Eduardo Blanco Marigorta, Eduardo Álvarez Álvarez, Antonio Navarro Manso, Víctor Manuel Fernández Pacheco, Elena Antuña Yudego, Juan Luis Carús Candás

“…Air pollution is one of the consequences of the industrial development, which causes a lot of health and environmental problems. For these reasons, the quality…”
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UBE3B Is a Calmodulin-regulated, Mitochondrion-associated E3 Ubiquitin Ligase by Braganza, Andrea, Li, Jianfeng, Zeng, Xuemei, Yates, Nathan A., Dey, Nupur B., Andrews, Joel, Clark, Jennifer, Zamani, Leila, Wang, Xiao-hong, St. Croix, Claudette, O'Sullivan, Roderick, Garcia-Exposito, Laura, Brodsky, Jeffrey L., Sobol, Robert W.

“…Recent genome-wide studies found that patients with hypotonia, developmental delay, intellectual disability, congenital anomalies, characteristic facial…”
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Viral infection: Moving through complex and dynamic cell-membrane structures by Barroso-González, Jonathan, García-Expósito, Laura, Puigdomènech, Isabel, de Armas-Rillo, Laura, Machado, José-David, Blanco, Julià, Valenzuela-Fernández, Agustín

“…Viruses have developed different survival strategies in host cells by crossing cell-membrane compartments, during different steps of their viral life cycle. In…”
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Alterations in cholesterol metabolism restrict HIV-1 trans infection in nonprogressors by Rappocciolo, Giovanna, Jais, Mariel, Piazza, Paolo, Reinhart, Todd A, Berendam, Stella J, Garcia-Exposito, Laura, Gupta, Phalguni, Rinaldo, Charles R

“…ABSTRACT HIV-1-infected nonprogressors (NP) inhibit disease progression for years without antiretroviral therapy. Defining the mechanisms for this resistance…”
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Alterations in Cholesterol Metabolism Restrict HIV-1  italic toggle="yes">Trans /italic> Infection in Nonprogressors by Giovanna Rappocciolo, Mariel Jais, Paolo Piazza, Todd A. Reinhart, Stella J. Berendam, Laura Garcia-Exposito, Phalguni Gupta, Charles R. Rinaldo

“…ABSTRACT HIV-1-infected nonprogressors (NP) inhibit disease progression for years without antiretroviral therapy. Defining the mechanisms for this resistance…”
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