Search Results - "Laura G. Estévez"
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Evidence-Based Use of Neoadjuvant Taxane in Operable and Inoperable Breast Cancer
Published in Clinical cancer research (15-05-2004)“…Neoadjuvant chemotherapy (NC) is standard therapy for patients with locally advanced breast cancer and is increasingly used for early-stage operable disease…”
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An Overview of Letrozole in Postmenopausal Women with Hormone-Responsive Breast Cancer
Published in Advances in therapy (01-12-2011)“…Third-generation aromatase inhibitors (AIs) have proven to be superior to tamoxifen in terms of time to disease progression in patients with hormone receptor…”
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Paclitaxel With Inhibitor of Apoptosis Antagonist, LCL161, for Localized Triple-Negative Breast Cancer, Prospectively Stratified by Gene Signature in a Biomarker-Driven Neoadjuvant Trial
Published in Journal of clinical oncology (01-11-2018)“…There are currently no targeted therapies approved for triple-negative breast cancer (TNBC). A tumor necrosis factor α ( TNFα)-based gene expression signature…”
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An analysis of the association between breast density and body mass index with breast cancer molecular subtypes in early breast cancer: data from a Spanish population
Published in Clinical & translational oncology (01-10-2024)“…Purpose Breast cancer is an important health problem, like obesity and dyslipidemia, with a strong association between body mass index (BMI) and breast cancer…”
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Optofluidic device for the quantification of circulating tumor cells in breast cancer
Published in Scientific reports (16-06-2017)“…Metastatic cancer patients require a continuous monitoring during the sequential treatment cycles to carefully evaluate their disease evolution. Repetition of…”
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Molecular effects of lapatinib in patients with HER2 positive ductal carcinoma in situ
Published in Breast cancer research : BCR (04-09-2014)“…Human epidermal growth factor receptor 2 (HER2) amplification is frequent in ductal carcinoma in situ (DCIS) of the breast and is associated with poorly…”
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Current perspectives of treatment of ductal carcinoma in situ
Published in Cancer treatment reviews (01-11-2010)“…Summary DCIS is a genetically diverse group of diseases with different prognosis. The similarities between DCIS and ductal infiltrating carcinoma (DIC) suggest…”
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Evaluation of international treatment guidelines and prognostic tests for the treatment of early breast cancer
Published in Cancer treatment reviews (01-12-2008)“…Summary The clinical decision to treat early-stage breast cancer with adjuvant chemotherapy is sometimes a difficult one because 70–80% of patients who receive…”
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Weekly docetaxel as neoadjuvant chemotherapy for stage II and III breast cancer: Efficacy and correlation with biological markers in a phase II, multicenter study
Published in Clinical cancer research (01-02-2003)“…This is one of the first reports of weekly docetaxel (Taxotere) in the neoadjuvant treatment of stage II and III breast cancer. We evaluated docetaxel's…”
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A Phase II Study of Capecitabine and Vinorelbine in Patients with Metastatic Breast Cancer Pretreated with Anthracyclines and Taxanes
Published in Clinical breast cancer (01-04-2008)“…Abstract Purpose The aim of this study was to evaluate the efficacy and safety of capecitabine in combination with vinorelbine in patients with metastatic…”
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Evidence-based use of taxanes in the adjuvant setting of breast cancer. A review of randomized phase III trials
Published in Cancer treatment reviews (01-08-2007)“…Summary Six major randomized clinical trials evaluating the role of taxanes in the adjuvant setting of breast cancer have demonstrated significant improvements…”
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Biweekly docetaxel and gemcitabine as neoadjuvant chemotherapy in stage II and III breast cancer patients: Preliminary results of a phase II and pharmacogenomic study
Published in Seminars in oncology (01-04-2004)“…The purpose of this study is to evaluate the efficacy and safety of a biweekly neoadjuvant docetaxel/gemcitabine regimen in patients with histologically…”
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The Use of Taxanes in the Neoadjuvant Treatment of Breast Cancer: A Review of Randomized Phase II/III Trials
Published in Clinical breast cancer (01-10-2007)“…Abstract This review examines all randomized studies that evaluated the role of taxanes in the neoadjuvant treatment of breast cancer and have reported results…”
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Abstract P4-03-39: Breast density and Body Mass Index association with breast cancer molecular subtypes in early breast cancer Spanish population
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…Obesity is a major health problem and is closely related to the incidence and progression of breast cancer (BC). Likewise, mammogram breast density (MBD) is a…”
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Neoadjuvant endocrine therapy for breast cancer: past, present and future
Published in Anti-cancer drugs (01-04-2008)“…Combined treatments together with surgery, radiotherapy, chemotherapy, and endocrine therapy have contributed substantially to the improved survival rate in…”
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Advanced breast cancer: chemotherapy phase III trials that change a standard
Published in Anti-cancer drugs (01-08-2007)“…At the present time, there is not a standard regimen in upfront metastatic setting for breast cancer. A wide variety of regimens which includes anthracyclines,…”
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Neoadjuvant chemotherapy in breast cancer
Published in Clinical & translational oncology (01-06-2004)Get full text
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Gemcitabine and carboplatin for patients with advanced non-small cell lung cancer
Published in Seminars in oncology (01-06-2001)“…The survival of patients with advanced non-small cell lung cancer remains poor. Cisplatin-based chemotherapy produces a modest benefit in survival compared…”
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Analysis of inactivation of PI3K/AKT/mTOR signaling pathway using neoadjuvant BKM120 in PI3KCA mutated early breast cancer
Published in Journal of clinical oncology (20-05-2014)“…Abstract only…”
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Can Onco type DX Recurrence Score (RS) be used in Luminal A and Luminal B breast cancer patients (pts) to predict the likely benefit of chemotherapy? A retrospective unicentric study in Spanish population
Published in Journal of clinical oncology (10-09-2013)“…Abstract only 40 Background: The 2011 St Gallen guidelines recommend the use of Ki67 as a surrogate marker for luminal A and Luminal B breast cancer subtypes…”
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