Search Results - "Laura B Goodman"
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A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis
Published in Nature (London) (15-06-2017)“…Diarrhoeal disease is responsible for 8.6% of global child mortality. Recent epidemiological studies found the protozoan parasite Cryptosporidium to be a…”
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2
Optimized conditions for Listeria, Salmonella and Escherichia whole genome sequencing using the Illumina iSeq100 platform with point-and-click bioinformatic analysis
Published in PloS one (30-11-2022)“…Whole-genome sequencing (WGS) data have become an integral component of public health investigations and clinical diagnostics. Still, many veterinary…”
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Feline respiratory disease complex: insights into the role of viral and bacterial co-infections
Published in Frontiers in microbiology (03-09-2024)“…Feline respiratory disease complex (FRDC) is a highly prevalent syndrome in cats that often result in fatal outcomes. FRDC etiology is complex, and often,…”
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4
Fecal indicator bacteria, fecal source tracking markers, and pathogens detected in two Hudson River tributaries
Published in Water research (Oxford) (15-03-2020)“…Volunteer monitoring in the Hudson River watershed since 2012 has identified that the Wallkill River and Rondout Creek tributary complex have elevated…”
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5
Lactococcus petauri sp. nov., isolated from an abscess of a sugar glider
Published in International journal of systematic and evolutionary microbiology (01-11-2017)“…A strain of lactic acid bacteria, designated 159469 , isolated from a facial abscess in a sugar glider, was characterized genetically and phenotypically. Cells…”
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6
Phylogeographic reconstruction of the emergence and spread of Powassan virus in the northeastern United States
Published in Proceedings of the National Academy of Sciences - PNAS (18-04-2023)“…Powassan virus is an emerging tick-borne virus of concern for public health, but very little is known about its transmission patterns and ecology. Here, we…”
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The deletion of the ORF1 and ORF71 genes reduces virulence of the neuropathogenic EHV-1 strain Ab4 without compromising host immunity in horses
Published in PloS one (15-11-2018)“…The equine herpesvirus type 1 (EHV-1) ORF1 and ORF71 genes have immune modulatory effects in vitro. Experimental infection of horses using virus mutants with…”
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Molecular detection using hybridization capture and next-generation sequencing reveals cross-species transmission of feline coronavirus type-1 between a domestic cat and a captive wild felid
Published in Microbiology spectrum (03-10-2024)“…Feline coronavirus (FCoV) infection normally causes mild or subclinical signs and is common in domestic cats. However, in some cats, FCoV infection can also…”
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Neonatal Immunization with a Single IL-4/Antigen Dose Induces Increased Antibody Responses after Challenge Infection with Equine Herpesvirus Type 1 (EHV-1) at Weanling Age
Published in PloS one (01-01-2017)“…Neonatal foals respond poorly to conventional vaccines. These vaccines typically target T-helper (Th) cell dependent B-cell activation. However, Th2-cell…”
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Noninvasive sampling of the small intestinal chyme for microbiome, metabolome and antimicrobial resistance genes in dogs, a proof of concept
Published in Animal microbiome (16-12-2023)“…The gastrointestinal microbiome and metabolome vary greatly throughout the different segments of the gastrointestinal tract, however current knowledge of…”
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A point mutation in a herpesvirus polymerase determines neuropathogenicity
Published in PLoS pathogens (01-11-2007)“…Infection with equid herpesvirus type 1 (EHV-1) leads to respiratory disease, abortion, and neurologic disorders in horses. Molecular epidemiology studies have…”
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Evolutionary reconstructions of the transferrin receptor of Caniforms supports canine parvovirus being a re-emerged and not a novel pathogen in dogs
Published in PLoS pathogens (01-05-2012)“…Parvoviruses exploit transferrin receptor type-1 (TfR) for cellular entry in carnivores, and specific interactions are key to control of host range. We show…”
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13
Recent Zoonotic Spillover and Tropism Shift of a Canine Coronavirus Is Associated with Relaxed Selection and Putative Loss of Function in NTD Subdomain of Spike Protein
Published in Viruses (21-04-2022)“…A canine coronavirus (CCoV) has now been reported from two independent human samples from Malaysia (respiratory, collected in 2017-2018; CCoV-HuPn-2018) and…”
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Positive selection, genetic recombination, and intra-host evolution in novel equine coronavirus genomes and other members of the Embecovirus subgenus
Published in Microbiology spectrum (07-10-2024)“…There are several examples of coronaviruses in the Betacoronavirus subgenus that have jumped from an animal to the human host. Studying how evolutionary…”
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15
Method comparison of targeted influenza A virus typing and whole-genome sequencing from respiratory specimens of companion animals
Published in Journal of veterinary diagnostic investigation (01-03-2021)“…Epidemics of H3N8 and H3N2 influenza A viruses (IAVs) in dogs, along with recognition of spillover infections from IAV strains typically found in humans or…”
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DNA Extraction and Host Depletion Methods Significantly Impact and Potentially Bias Bacterial Detection in a Biological Fluid
Published in mSystems (01-06-2021)“…Untargeted sequencing of nucleic acids present in food can inform the detection of food safety and origin, as well as product tampering and mislabeling issues…”
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Enhancing the one health initiative by using whole genome sequencing to monitor antimicrobial resistance of animal pathogens: Vet-LIRN collaborative project with veterinary diagnostic laboratories in United States and Canada
Published in BMC veterinary research (06-05-2019)“…Antimicrobial resistance (AMR) of bacterial pathogens is an emerging public health threat. This threat extends to pets as it also compromises our ability to…”
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Investigation of the prevalence of neurologic equine herpes virus type 1 (EHV-1) in a 23-year retrospective analysis (1984–2007)
Published in Veterinary microbiology (18-11-2009)“…A single nucleotide polymorphism in the equine herpesvirus 1 (EHV-1) DNA polymerase gene (ORF30 A2254 to G) has been associated with clinical signs of equine…”
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Immunological Correlates of Vaccination and Infection for Equine Herpesvirus 1
Published in Clinical and Vaccine Immunology (01-02-2012)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Effect of antimicrobial administration on fecal microbiota of critically ill dogs: dynamics of antimicrobial resistance over time
Published in Animal microbiome (04-06-2022)“…Multidrug resistance in companion animals poses significant risks to animal and human health. Prolonged antimicrobial drug (AMD) treatment in animals is a…”
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