Search Results - "Laumas, Sandeep"
-
1
In vivo assessment of a delayed release formulation of larazotide acetate indicated for celiac disease using a porcine model
Published in PloS one (12-04-2021)“…There is no FDA approved therapy for the treatment of celiac disease (CeD), aside from avoidance of dietary gluten. Larazotide acetate (LA) is a first in class…”
Get full text
Journal Article -
2
Larazotide acetate induces recovery of ischemia-injured porcine jejunum via repair of tight junctions
Published in PloS one (22-04-2021)“…Intestinal ischemia results in mucosal injury, including paracellular barrier loss due to disruption of tight junctions. Larazotide acetate (LA), a small…”
Get full text
Journal Article -
3
Co-loading of an anthracycline analogue Pirarubicin and Salinomycin in a 1:3 ratio into Quatramerbiodegradable polymeric nanoparticles synergistically inhibit growth of triple-negative breast cancer
Published in Journal of clinical oncology (20-05-2021)“…Abstract only e15047 Background: Triple negative breast cancer (TNBC) accounts for about 10-15% of all breast cancers and differ from other types of invasive…”
Get full text
Journal Article -
4
Abstract 491: Encapsulation of the stem cell inhibitor Salinomycin in novel QUATRAMER sustained injectable suspension (HSB-1216) for the treatment of small cell lung cancer
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Small cell lung cancer (SCLC) represents approximately 15% of all cases of lung cancer. SCLC patients have a poor prognosis and limited treatment…”
Get full text
Journal Article -
5
Abstract 492: A Novel QUATRAMER sustained injectable suspension for the intracellular delivery of Salinomycin, a stem cell inhibitor (HSB-1216), for the treatment of triple negative breast cancer
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Triple-negative breast cancer (TNBC) accounts for approximately 15-20 % of all breast cancers, is an aggressive disease with a poor prognosis, and…”
Get full text
Journal Article -
6
-
7
-
8
Su1017 – Establishment and Characterization of a Leaky Porcine Jejunal Cell Line Grown As a 2-Dimensional Monolayer Using Crypt Culture Media and Their Response to the Tight Junction Agent Larazotide Acetate
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2019)Get full text
Journal Article -
9
-
10
-
11
Sa1517 – Larazotide Acetate Prevents and Rescues from Ethanolinduced Permeability Changes in an In Vitro Model System
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2019)Get full text
Journal Article