Search Results - "Laulederkind, Stanley J. F."

Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins by Holmes, Roger S, Wright, Matthew W, Laulederkind, Stanley J. F, Cox, Laura A, Hosokawa, Masakiyo, Imai, Teruko, Ishibashi, Shun, Lehner, Richard, Miyazaki, Masao, Perkins, Everett J, Potter, Phillip M, Redinbo, Matthew R, Robert, Jacques, Satoh, Tetsuo, Yamashita, Tetsuro, Yan, Bingfan, Yokoi, Tsuyoshi, Zechner, Rudolf, Maltais, Lois J

“…Mammalian carboxylesterase (CES or Ces) genes encode enzymes that participate in xenobiotic, drug, and lipid metabolism in the body and are members of at least…”
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The Year of the Rat: The Rat Genome Database at 20: a multi-species knowledgebase and analysis platform by Smith, Jennifer R, Hayman, G Thomas, Wang, Shur-Jen, Laulederkind, Stanley J F, Hoffman, Matthew J, Kaldunski, Mary L, Tutaj, Monika, Thota, Jyothi, Nalabolu, Harika S, Ellanki, Santoshi L R, Tutaj, Marek A, De Pons, Jeffrey L, Kwitek, Anne E, Dwinell, Melinda R, Shimoyama, Mary E

“…Abstract Formed in late 1999, the Rat Genome Database (RGD, https://rgd.mcw.edu) will be 20 in 2020, the Year of the Rat. Because the laboratory rat, Rattus…”
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Disease Ontology: improving and unifying disease annotations across species by Bello, Susan M, Shimoyama, Mary, Mitraka, Elvira, Laulederkind, Stanley J F, Smith, Cynthia L, Eppig, Janan T, Schriml, Lynn M

“…Model organisms are vital to uncovering the mechanisms of human disease and developing new therapeutic tools. Researchers collecting and integrating relevant…”
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The rat genome database curators: who, what, where, why by Shimoyama, Mary, Hayman, G Thomas, Laulederkind, Stanley J F, Nigam, Rajni, Lowry, Timothy F, Petri, Victoria, Smith, Jennifer R, Wang, Shur-Jen, Munzenmaier, Diane H, Dwinell, Melinda R, Twigger, Simon N, Jacob, Howard J

“…  Established in 1999, RGD is the premier repository of rat genomic and genetic data and currently houses over 33,421 rat genes as well as human and mouse…”
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Exploring human disease using the Rat Genome Database by Shimoyama, Mary, Laulederkind, Stanley J F, De Pons, Jeff, Nigam, Rajni, Smith, Jennifer R, Tutaj, Marek, Petri, Victoria, Hayman, G Thomas, Wang, Shur-Jen, Ghiasvand, Omid, Thota, Jyothi, Dwinell, Melinda R

“…Rattus norvegicus, the laboratory rat, has been a crucial model for studies of the environmental and genetic factors associated with human diseases for over…”
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Ontological Analysis of Coronavirus Associated Human Genes at the COVID-19 Disease Portal by Wang, Shur-Jen, Brodie, Kent C, De Pons, Jeffrey L, Demos, Wendy M, Gibson, Adam C, Hayman, G Thomas, Hill, Morgan L, Kaldunski, Mary L, Lamers, Logan, Laulederkind, Stanley J F, Nalabolu, Harika S, Thota, Jyothi, Thorat, Ketaki, Tutaj, Marek A, Tutaj, Monika, Vedi, Mahima, Zacher, Stacy, Smith, Jennifer R, Dwinell, Melinda R, Kwitek, Anne E

“…The COVID-19 pandemic stemmed a parallel upsurge in the scientific literature about SARS-CoV-2 infection and its health burden. The Rat Genome Database (RGD)…”
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Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology by Lovering, Ruth C, Roncaglia, Paola, Howe, Douglas G, Laulederkind, Stanley J F, Khodiyar, Varsha K, Berardini, Tanya Z, Tweedie, Susan, Foulger, Rebecca E, Osumi-Sutherland, David, Campbell, Nancy H, Huntley, Rachael P, Talmud, Philippa J, Blake, Judith A, Breckenridge, Ross, Riley, Paul R, Lambiase, Pier D, Elliott, Perry M, Clapp, Lucie, Tinker, Andrew, Hill, David P

“…A systems biology approach to cardiac physiology requires a comprehensive representation of how coordinated processes operate in the heart, as well as the…”
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The Human Phenotype Ontology in 2017 by Köhler, Sebastian, Vasilevsky, Nicole A, Engelstad, Mark, Foster, Erin, McMurry, Julie, Aymé, Ségolène, Baynam, Gareth, Bello, Susan M, Boerkoel, Cornelius F, Boycott, Kym M, Brudno, Michael, Buske, Orion J, Chinnery, Patrick F, Cipriani, Valentina, Connell, Laureen E, Dawkins, Hugh J S, DeMare, Laura E, Devereau, Andrew D, de Vries, Bert B A, Firth, Helen V, Freson, Kathleen, Greene, Daniel, Hamosh, Ada, Helbig, Ingo, Hum, Courtney, Jähn, Johanna A, James, Roger, Krause, Roland, F Laulederkind, Stanley J, Lochmüller, Hanns, Lyon, Gholson J, Ogishima, Soichi, Olry, Annie, Ouwehand, Willem H, Pontikos, Nikolas, Rath, Ana, Schaefer, Franz, Scott, Richard H, Segal, Michael, Sergouniotis, Panagiotis I, Sever, Richard, Smith, Cynthia L, Straub, Volker, Thompson, Rachel, Turner, Catherine, Turro, Ernest, Veltman, Marijcke W M, Vulliamy, Tom, Yu, Jing, von Ziegenweidt, Julie, Zankl, Andreas, Züchner, Stephan, Zemojtel, Tomasz, Jacobsen, Julius O B, Groza, Tudor, Smedley, Damian, Mungall, Christopher J, Haendel, Melissa, Robinson, Peter N

“…Deep phenotyping has been defined as the precise and comprehensive analysis of phenotypic abnormalities in which the individual components of the phenotype are…”
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PhenoMiner: a quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease by Wang, Shur-Jen, Laulederkind, Stanley J F, Hayman, G Thomas, Petri, Victoria, Liu, Weisong, Smith, Jennifer R, Nigam, Rajni, Dwinell, Melinda R, Shimoyama, Mary

“…Rats have been used extensively as animal models to study physiological and pathological processes involved in human diseases. Numerous rat strains have been…”
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The Rat Genome Database 2015: genomic, phenotypic and environmental variations and disease by Shimoyama, Mary, De Pons, Jeff, Hayman, G Thomas, Laulederkind, Stanley J F, Liu, Weisong, Nigam, Rajni, Petri, Victoria, Smith, Jennifer R, Tutaj, Marek, Wang, Shur-Jen, Worthey, Elizabeth, Dwinell, Melinda, Jacob, Howard

“…The Rat Genome Database (RGD, http://rgd.mcw.edu) provides the most comprehensive data repository and informatics platform related to the laboratory rat, one…”
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Rare disease research resources at the Rat Genome Database by Kaldunski, Mary L, Smith, Jennifer R, Brodie, Kent C, De Pons, Jeffrey L, Demos, Wendy M, Gibson, Adam C, Hayman, G Thomas, Lamers, Logan, Laulederkind, Stanley J F, Thorat, Ketaki, Thota, Jyothi, Tutaj, Marek A, Tutaj, Monika, Vedi, Mahima, Wang, Shur-Jen, Zacher, Stacy, Dwinell, Melinda R, Kwitek, Anne E

“…Abstract Rare diseases individually affect relatively few people, but as a group they impact considerable numbers of people. The Rat Genome Database…”
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Analysis of disease-associated objects at the Rat Genome Database by Wang, Shur-Jen, Laulederkind, Stanley J F, Hayman, G T, Smith, Jennifer R, Petri, Victoria, Lowry, Timothy F, Nigam, Rajni, Dwinell, Melinda R, Worthey, Elizabeth A, Munzenmaier, Diane H, Shimoyama, Mary, Jacob, Howard J

“…The Rat Genome Database (RGD) is the premier resource for genetic, genomic and phenotype data for the laboratory rat, Rattus norvegicus. In addition to…”
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Defective expression of Tamm-Horsfall protein/uromodulin in COX-2-deficient mice increases their susceptibility to urinary tract infections by Dou, Wenkai, Thompson-Jaeger, Sandra, Laulederkind, Stanley J F, Becker, John W, Montgomery, Julia, Ruiz-Bustos, Eduardo, Hasty, David L, Ballou, Leslie R, Eastman, P Scott, Srichai, Betsy, Breyer, Matthew D, Raghow, Rajendra

“…Mice lacking a functional cyclooxygenase-2 (COX-2) gene develop abnormal kidneys that contain hypoplastic glomeruli and reduced proximal tubular mass, and they…”
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Model organism data evolving in support of translational medicine by Howe, Douglas G., Blake, Judith A., Bradford, Yvonne M., Bult, Carol J., Calvi, Brian R., Engel, Stacia R., Kadin, James A., Kaufman, Thomas C., Kishore, Ranjana, Laulederkind, Stanley J. F., Lewis, Suzanna E., Moxon, Sierra A. T., Richardson, Joel E., Smith, Cynthia

“…Model organism databases (MODs) have been collecting and integrating biomedical research data for 30 years and were designed to meet specific needs of each…”
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The Rat Genome Database 2013--data, tools and users by Laulederkind, Stanley J F, Hayman, G Thomas, Wang, Shur-Jen, Smith, Jennifer R, Lowry, Timothy F, Nigam, Rajni, Petri, Victoria, de Pons, Jeff, Dwinell, Melinda R, Shimoyama, Mary, Munzenmaier, Diane H, Worthey, Elizabeth A, Jacob, Howard J

“…The Rat Genome Database (RGD) was started >10 years ago to provide a core genomic resource for rat researchers. Currently, RGD combines genetic, genomic,…”
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Both Constitutive and Inducible Prostaglandin H Synthase Affect Dermal Wound Healing in Mice by Laulederkind, Stanley J F, Thompson-Jaeger, Sandra, Goorha, Sarita, Chen, Qingshan, Fu, Amina, Rho, Jae-Young, Ballou, Leslie R, Raghow, Rajendra

“…In an attempt to define the roles of prostaglandin H synthase 1 (PGHS-1, cyclooxygenase-1, COX-1) and prostaglandin H synthase 2 (PGHS-2, cyclooxygenase-2,…”
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Augmenting the disease ontology improves and unifies disease annotations across species by Bello, Susan M., Shimoyama, Mary, Mitraka, Elvira, Laulederkind, Stanley J. F., Smith, Cynthia L., Eppig, Janan T., Schriml, Lynn M.

“…Model organisms are vital to uncovering the mechanisms of human disease and developing new therapeutic tools. Researchers collecting and integrating relevant…”
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The Rat Genome Database: Genetic, Genomic, and Phenotypic Data Across Multiple Species by Laulederkind, Stanley J F, Hayman, G Thomas, Wang, Shur-Jen, Kaldunski, Mary L, Vedi, Mahima, Demos, Wendy M, Tutaj, Monika, Smith, Jennifer R, Lamers, Logan, Gibson, Adam C, Thorat, Ketaki, Thota, Jyothi, Tutaj, Marek A, de Pons, Jeffrey L, Dwinell, Melinda R, Kwitek, Anne E

“…The laboratory rat, Rattus norvegicus, is an important model of human health and disease, and experimental findings in the rat have relevance to human…”
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Comprehensive coverage of cardiovascular disease data in the disease portals at the Rat Genome Database by Wang, Shur-Jen, Laulederkind, Stanley J F, Hayman, G Thomas, Petri, Victoria, Smith, Jennifer R, Tutaj, Marek, Nigam, Rajni, Dwinell, Melinda R, Shimoyama, Mary

“…Cardiovascular diseases are complex diseases caused by a combination of genetic and environmental factors. To facilitate progress in complex disease research,…”
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Rat Genome Database: a unique resource for rat, human, and mouse quantitative trait locus data by Nigam, Rajni, Laulederkind, Stanley J F, Hayman, G Thomas, Smith, Jennifer R, Wang, Shur-Jen, Lowry, Timothy F, Petri, Victoria, De Pons, Jeff, Tutaj, Marek, Liu, Weisong, Jayaraman, Pushkala, Munzenmaier, Diane H, Worthey, Elizabeth A, Dwinell, Melinda R, Shimoyama, Mary, Jacob, Howard J

“…The rat has been widely used as a disease model in a laboratory setting, resulting in an abundance of genetic and phenotype data from a wide variety of…”
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