Search Results - "Laughlin, N K"
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Succimer and the Urinary Excretion of Essential Elements in a Primate Model of Childhood Lead Exposure
Published in Toxicological sciences (01-04-2000)“…Succimer is considered to be a safe and effective treatment for lead (Pb) poisoning, since it reduces body Pb levels without an apparent diuresis of other…”
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Succimer and the Reduction of Tissue Lead in Juvenile Monkeys
Published in Toxicology and applied pharmacology (01-08-2000)“…The extent to which succimer (2,3-dimercaptosuccinic acid, DMSA) chelation reduces target organ lead (Pb) levels, including the skeleton, relative to the…”
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Efficacy of Succimer Chelation for Reducing Brain Lead in a Primate Model of Human Lead Exposure
Published in Toxicology and applied pharmacology (15-12-1999)“…The extent to which succimer (meso-2,3-dimercaptosuccinic acid [DMSA], Chemet) reduces brain lead (Pb) levels may be a primary consideration in evaluating its…”
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Otoacoustic emission, evoked potential, and behavioral auditory thresholds in the rhesus monkey ( Macaca mulatta)
Published in Hearing research (01-10-1999)“…Distortion product otoacoustic emission (DPOAE), auditory brainstem evoked response (ABR), and behavioral thresholds were recorded in a group of 15 adult…”
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Understanding the NIH review process: a brief guide to writing grant proposals in neurotoxicology
Published in Neurotoxicology (Park Forest South) (01-02-1999)“…During the past two years, the National Institutes of Health have made significant changes in the review process for investigator-initiated research grant…”
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Lead Effects on Neurobehavioral Development in the Neonatal Rhesus Monkey ( Macaca mulatta)
Published in Neurotoxicology and teratology (01-11-1999)“…Effects of lead exposure on behavioral development during the first month of postnatal life were examined in rhesus monkeys using a multi-item assessment scale…”
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The effects of lead on otoacoustic emissions and auditory evoked potentials in monkeys
Published in Neurotoxicology and teratology (01-11-1995)“…Auditory functioning was assessed in two groups of adult rhesus monkeys (11 years of age). One ( n = 11) received modest exposure to lead early in life and the…”
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Effects of lead on luteal function in rhesus monkeys
Published in Biology of reproduction (01-12-1989)“…Exposure to lead in the workplace or home environment has been implicated as a cause of decreased fertility in women. In a previous study, as part of our…”
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Geriatric Bone Lead Metabolism in a Female Nonhuman Primate Population
Published in Environmental research (01-02-1997)“…A geriatric rhesus monkey (Macaca mulatta) population, previously exposed to lead, was investigated using109Cd K X-ray fluorescence (K XRF) to determine…”
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Effects of perinatal PCB exposure on discrimination-reversal learning in monkeys
Published in Neurotoxicology and teratology (01-05-1989)“…Monkeys exposed to PCB mixtures during gestation and lactation were tested on two-choice discrimination-reversal learning (DR). In Experiment 1, offspring of…”
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Distortion product otoacoustic emissions in Macaca mulatta and humans
Published in Hearing research (01-09-1995)“…Distortion product otoacoustic emissions (DPOAEs) were compared in eight rhesus monkeys ( Macaca mulatta) and eight normal hearing humans. DPOAEs were recorded…”
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Lead exposure and diet: differential effects on social development in the rhesus monkey
Published in Neurotoxicology and teratology (1991)“…Infant rhesus monkeys ingested 0 or 1.0 mg/kg lead acetate daily from birth to one year postpartum in dietary milk. Half the monkeys in each group were offered…”
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Inguinal hernias, endometriosis, and other adverse outcomes in rhesus monkeys following lead exposure
Published in Neurotoxicology and teratology (01-09-2003)“…The Harlow Center for Biological Psychology (HCBP) has a cohort of rhesus monkeys that were exposed to low concentrations of lead acetate in utero or as…”
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Exploring a partially enclosed space by lead-exposed female rhesus monkeys
Published in Neurotoxicology and teratology (01-03-2001)“…Beginning on Day 8 postpartum, lead acetate was administered to female rhesus monkeys ( n=48). Their blood lead levels rose to 35–40 μg/dl (the level…”
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The Effects of Elevated Blood Lead Levels and Succimer Chelation Therapy on Physical Growth in Developing Rhesus Monkeys
Published in Environmental research (01-09-2001)“…Seventy-two female rhesus monkeys were randomly assigned to three lead exposure conditions (none, birth to 1 year, birth to 2 years). In a completely crossed…”
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In memoriam: Robert W. Bell, November 22, 1931- September 16, 2000
Published in Developmental psychobiology (01-03-2001)Get full text
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The effects of succimer chelation therapy on auditory function in rhesus monkeys
Published in Neurotoxicology and teratology (01-11-2001)“…Sixty-six female rhesus monkeys were randomly assigned to three lead exposure conditions (none, from birth to 1 year, and from birth to 2 years) by two…”
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The development of auditory event related potentials in the rhesus monkey (Macaca mulatta)
Published in Developmental psychobiology (01-01-1999)“…Auditory event related potentials were recorded from neonatal, 3‐month, and 3‐year old rhesus monkeys. Auditory brainstem evoked responses (ABRs) were reliably…”
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