Search Results - "Laughlin, Mark A."

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  1. 1

    Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial by Wilcock, Gordon K, DM, Black, Sandra E, MD, Hendrix, Suzanne B, PhD, Zavitz, Kenton H, PhD, Swabb, Edward A, PhD, Laughlin, Mark A, MD

    Published in Lancet neurology (01-06-2008)
    “…Summary Background The amyloid-β peptide Aβ42 has been implicated in the pathogenesis of Alzheimer's disease (AD). We aimed to test the effects of…”
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  2. 2

    Potent Inhibition of Human Immunodeficiency Virus Type 1 Replication by an Intracellular Anti-Rev Single-Chain Antibody by Duan, Lingxun, Bagasra, Omar, Laughlin, Mark A., Oakes, Joseph W., Pomerantz, Roger J.

    “…Human immunodeficiency virus type 1 (HIV-1) has a complex life cycle, which has made it a difficult target for conventional therapeutic modalities. A…”
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  3. 3

    Amphipathic Domains in the C Terminus of the Transmembrane Protein (gp41) Permeabilize HIV-1 Virions: A Molecular Mechanism Underlying Natural Endogenous Reverse Transcription by Zhang, Hui, Dornadula, Geethanjali, Alur, Prasad, Laughlin, Mark A., Pomerantz, Roger J.

    “…Reverse transcription of HIV-1, without detergent or amphipathic peptide-induced permeability of the viral envelope, has been demonstrated to occur in the…”
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  4. 4

    Entry of human immunodeficiency virus-1 into glial cells proceeds via an alternate, efficient pathway by Harouse, J M, Laughlin, M A, Pletcher, C, Friedman, H M, Gonzalez-Scarano, F

    Published in Journal of leukocyte biology (01-06-1991)
    “…Although the CD4 molecule is the cellular receptor for human immunodeficiency virus-1 (HIV-1) in cells of the lymphocyte/monocyte lineage, a number of…”
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    Sodium butyrate treatment of cells latently infected with HIV-1 results in the expression of unspliced viral RNA by Laughlin, M A, Zeichner, S, Kolson, D, Alwine, J C, Seshamma, T, Pomerantz, R J, Gonzalez-Scarano, F

    Published in Virology (New York, N.Y.) (01-10-1993)
    “…To investigate potential mechanisms for HIV-1 proviral latency, we generated a set of chronically HIV-1 infected and stably long terminal…”
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  8. 8

    Use of Amphotericin B During Pregnancy: Case Report and Review by Dean, James L., Wolf, Judith E., Ranzini, Angela C., Laughlin, Mark A.

    Published in Clinical infectious diseases (01-03-1994)
    “…Unlike the situation with many antimicrobial agents, there is limited experience with the use of amphotericin B during pregnancy. Although reports of fungal…”
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  9. 9

    Human choroid plexus cells can be latently infected with human immunodeficiency virus by Harouse, J M, Wroblewska, Z, Laughlin, M A, Hickey, W F, Schonwetter, B S, Gonzalez-Scarano, F

    Published in Annals of neurology (01-04-1989)
    “…The human immunodeficiency virus (HIV) penetrates the central nervous system, particularly the cerebrospinal fluid, early in the course of HIV infection, and…”
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    Cellular latency in HIV-1 infection by Laughlin, M A, Pomerantz, R J

    Published in Clinics in laboratory medicine (01-06-1994)
    “…There are multiple levels of transcriptional regulation that a cell can bring to bear on either native cellular genes or integrated proviral genes. One such…”
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