Search Results - "Laufenberg, Lacee J."

Interdependence of Muscle Atrophy and Bone Loss Induced by Mechanical Unloading by Lloyd, Shane A, Lang, Charles H, Zhang, Yue, Paul, Emmanuel M, Laufenberg, Lacee J, Lewis, Gregory S, Donahue, Henry J

“…ABSTRACT Mechanical unloading induces muscle atrophy and bone loss; however, the time course and interdependence of these effects is not well defined. We…”
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Alcohol Acutely Antagonizes Refeeding-Induced Alterations in the Rag GTPase-Ragulator Complex in Skeletal Muscle by Laufenberg, Lacee J, Crowell, Kristen T, Lang, Charles H

“…The Ragulator protein complex is critical for directing the Rag GTPase proteins and mTORC1 to the lysosome membrane mediating amino acid-stimulated protein…”
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Sepsis-induced changes in amino acid transporters and leucine signaling via mTOR in skeletal muscle by Laufenberg, Lacee J., Pruznak, Anne M., Navaratnarajah, Maithili, Lang, Charles H.

“…The present study tested the hypothesis that sepsis-induced leucine (Leu) resistance in skeletal muscle is associated with a down-regulation of amino acid…”
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Modulation of voltage-gated Ca2+ channels by G protein-coupled receptors in celiac-mesenteric ganglion neurons of septic rats by Farrag, Mohamed, Laufenberg, Lacee J, Steiner, Jennifer L, Weller, Gregory E, Lang, Charles H, Ruiz-Velasco, Victor

“…Septic shock, the most severe complication associated with sepsis, is manifested by tissue hypoperfusion due, in part, to cardiovascular and autonomic…”
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Nociceptin receptor signaling in sympathetic neurons from septic rats by Laufenberg, Lacee J., MD, Weller, Gregory E., MD, PhD, Lang, Charles H., PhD, Ruiz-Velasco, Victor, PhD

“…Abstract Background The endogenous opioid peptide, nociception (Noc), contributes to the regulation of systemic blood pressure and regional blood flow. Recent…”
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Chronic Alcohol Consumption, but not Acute Intoxication, Decreases In Vitro Skeletal Muscle Contractile Function by Crowell, Kristin T., Laufenberg, Lacee J., Lang, Charles H.

“…Background Skeletal muscle myopathy accompanying chronic alcohol misuse results in part from a decrease in protein synthesis typically observed in type II‐rich…”
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Salutary effect of aurintricarboxylic acid on endotoxin- and sepsis-induced changes in muscle protein synthesis and inflammation by Laufenberg, Lacee J, Kazi, Abid A, Lang, Charles H

“…Small molecule nonpeptidyl molecules are potentially attractive drug candidates as adjunct therapies in the treatment of sepsis-induced metabolic…”
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Prospective validation and application of the Trauma-Specific Frailty Index: Results of an American Association for the Surgery of Trauma multi-institutional observational trial by Joseph, Bellal, Saljuqi, Abdul Tawab, Amos, Joseph D., Teichman, Amanda, Whitmill, Melissa L., Anand, Tanya, Hosseinpour, Hamidreza, Burruss, Sigrid K., Dunn, Julie A., Najafi, Kaveh, Godat, Laura N., Enniss, Toby M., Shoultz, Thomas H., Egodage, Tanya, Bongiovanni, Tasce, Hazelton, Joshua P., Colling, Kristin P., Costantini, Todd W., Stein, Deborah M., Schroeppel, Thomas J., Nahmias, Jeffry

“…The frailty index is a known predictor of adverse outcomes in geriatric patients. Trauma-Specific Frailty Index (TSFI) was created and validated at a single…”
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The implications of poor nutritional status on outcomes of geriatric trauma patients by Hosseinpour, Hamidreza, Anand, Tanya, Bhogadi, Sai Krishna, Nelson, Adam, Hejazi, Omar, Castanon, Lourdes, Ghaedi, Arshin, Khurshid, Muhammad Haris, Magnotti, Louis J., Joseph, Bellal, Amos, Joseph D., Teichman, Amanda, Whitmill, Melissa L., Burruss, Sigrid K., Dunn, Julie A., Najafi, Kaveh, Godat, Laura N., Enniss, Toby M., Shoultz, Thomas H., Egodage, Tanya, Bongiovanni, Tasce, Hazelton, Joshua P., Colling, Kristin P., Costantini, Todd W., Stein, Deborah M., Schroeppel, Thomas J., Nahmias, Jeffry, El-Qawaqzeh, Khaled, Choron, Rachel L., Comish, Paul B., Leneweaver, Kyle, Palmer, Brandi, Truitt, Michael S., Farrell, Mike, Laufenberg, Lacee J., Lasso-Tay, Erica, Stillman, Zachery, Hass, Daniel T., Grossman, Heather M., Gordon, Darnell, Krause, Cassandra, Thomas, Jonathan

“…Malnutrition is shown to be associated with worse outcomes among surgical patients, yet its postdischarge outcomes in trauma patients are not clear. This study…”
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It is not all black and white: The effect of increasing severity of frailty on outcomes of geriatric trauma patients by Alizai, Qaidar, Colosimo, Christina, Hosseinpour, Hamidreza, Stewart, Collin, Bhogadi, Sai Krishna, Nelson, Adam, Spencer, Audrey L, Ditillo, Michael, Magnotti, Louis J, Joseph, Bellal

“…Frailty is associated with poor outcomes in trauma patients. However, the spectrum of physiologic deficits, once a patient is identified as frail, is unknown…”
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Modulation of Voltage-Gated Ca.sup.2+ Channels by G Protein-Coupled Receptors in Celiac-Mesenteric Ganglion Neurons of Septic Rats by Farrag, Mohamed, Laufenberg, Lacee J, Steiner, Jennifer L, Weller, Gregory E, Lang, Charles H, Ruiz-Velasco, Victor

“…Septic shock, the most severe complication associated with sepsis, is manifested by tissue hypoperfusion due, in part, to cardiovascular and autonomic…”
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Muscle atrophy produced by spinal cord injury (SCI) in rats decreases muscle protein synthesis without altering mTOR kinase activity by Lang, Charles H., Laufenberg, Lacee J, Pruznak, Anne, Swartz, Emily M., Holmes, Gregory M.

“…Abstract only SCI produces muscle atrophy and derangements in nutrient homeostasis; however, the mechanisms and temporal patterning of these co‐morbidities are…”
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Modulation of Voltage-Gated Ca2+ Channels by G Protein-Coupled Receptors in Celiac-Mesenteric Ganglion Neurons of Septic Rats: e0125566 by Farrag, Mohamed, Laufenberg, Lacee J, Steiner, Jennifer L, Weller, Gregory E, Lang, Charles H, Ruiz-Velasco, Victor

“…Septic shock, the most severe complication associated with sepsis, is manifested by tissue hypoperfusion due, in part, to cardiovascular and autonomic…”
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