Search Results - "Lauf, P K"

Regulation of K-Cl Cotransport: from Function to Genes by Adragna, N.C, Di Fulvio, M, Lauf, P.K

“…This review intends to summarize the vast literature on K-Cl cotransport (COT) regulation from a functional and genetic viewpoint. Special attention has been…”
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Erythrocyte K-Cl cotransport: properties and regulation by Lauf, P K, Bauer, J, Adragna, N C, Fujise, H, Zade-Oppen, A M, Ryu, K H, Delpire, E

“…Erythrocytes possess a Cl-dependent, Na-independent K transport system cotransporting K and Cl in a 1:1 stoichiometry that is membrane potential independent…”
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Signal transduction mechanisms of K+-Cl− cotransport regulation and relationship to disease by Adragna, N. C., Ferrell, C. M., Zhang, J., Di Fulvio, M., Temprana, C. F., Sharma, A., Fyffe, R. E. W., Cool, D. R., Lauf, P. K.

“…The K+‐Cl− cotransport (COT) regulatory pathways recently uncovered in our laboratory and their implication in disease state are reviewed. Three mechanisms of…”
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Role of protein kinases in regulating sheep erythrocyte K-Cl cotransport by Flatman, P W, Adragna, N C, Lauf, P K

“…K-Cl cotransport in sheep erythrocytes can be activated by treatment either with A-23187 and EDTA to reduce concentration of internal ionized Mg [Mg]i) to…”
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KCl co-transport: immunocytochemical and functional evidence for more than one KCC isoform in high K and low K sheep erythrocytes by Lauf, P.K, Zhang, J, Delpire, E, Fyffe, R.E.W, Mount, D.B, Adragna, N.C

“…KCl co-transport (COT) is significantly higher in low K (LK), L-antigen (L) positive, than in high K (HK), M-antigen (M) positive, sheep red blood cells…”
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Magnesium and ATP dependence of K-Cl co-transport in low K+ sheep red blood cells by Delpire, E, Lauf, P K

“…1. In low K+ (LK) sheep red blood cells, depletion of adenosine triphosphate (ATP) by glycolysis inhibition induced specific effects on ouabain-resistant…”
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Glutathione removal reveals kinases as common targets for K-Cl cotransport stimulation in sheep erythrocytes by Lauf, P K, Adragna, N C, Agar, N S

“…K-Cl cotransport is activated by swelling, lowering of cellular free Mg (Mgi), and thiol modification of erythrocytes. Direct actions by thiol reagents on the…”
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Temperature-induced functional deocclusion of thiols inhibitory for sheep erythrocyte K-Cl cotransport by Lauf, P K, Adragna, N C

“…In low-K sheep erythrocytes, K-Cl cotransport is activated by treatment with low concentrations of thiol reagents and by other interventions such as lowering…”
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Hydroxyurea affects cell morphology, cation transport, and red blood cell adhesion in cultured vascular endothelial cells by ADRAGNA, N. C, FONSECA, P, LAUF, P. K

“…Hydroxyurea (HU) significantly increases fetal hemoglobin (Hb) production and concomitantly affects passive erythrocyte K transport and cell volume in patients…”
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K+: Cl- cotransport: sulfhydryls, divalent cations, and the mechanism of volume activation in a red cell by LAUF, P. K

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Role of nitrite, a nitric oxide derivative, in K-Cl cotransport activation of low-potassium sheep red blood cells by Adragna, N C, Lauf, P K

“…K-Cl cotransport (COT) is the coupled movement of K and Cl, present in most cells, associated with regulatory volume decrease, susceptible to oxidation and…”
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Modulation of K-Cl cotransport in volume-clamped low-K sheep erythrocytes by pH, magnesium, and ATP by Ortiz-Carranza, O, Adragna, N C, Lauf, P K

“…Cellular pH, ionized Mg (Mgi2+), and MgATP concentration of red blood cells, concomitantly with cell volume, change transiently during circulation. The action…”
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KCl cotransport regulation and protein kinase G in cultured vascular smooth muscle cells by Adragna, N C, Zhang, J, Di Fulvio, M, Lincoln, T M, Lauf, P K

“…K-Cl cotransport is activated by vasodilators in erythrocytes and vascular smooth muscle cells and its regulation involves putative kinase/phosphatase…”
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Lithium and protein kinase C modulators regulate swelling-activated K-Cl cotransport and reveal a complete phosphatidylinositol cycle in low K sheep erythrocytes by Ferrell, C M, Lauf, P K, Wilson, B A, Adragna, N C

“…K-Cl cotransport (COT), a ouabain-insensitive, Cl-dependent bidirectional K flux, is ubiquitously present in all cells, plays a major role in ion and volume…”
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K-Cl cotransport, pH, and role of Mg in volume-clamped low-K sheep erythrocytes: three equilibrium states by Lauf, P K, Erdmann, A, Adragna, N C

“…Ouabain-resistant K efflux and Rb influx in Cl and NO3 media were studied in volume-clamped low-K (LK) sheep red blood cells (SRBC) with normal and…”
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K+‐Cl− cotransport: ‘to be or not to be’ oxygen sensitive by Lauf, Peter K.

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Foreign anions modulate volume set point of sheep erythrocyte K-Cl cotransport by Lauf, P K

“…Preequilibration at 37 degrees C in isosmotic media with Cl replaced by lyotropic (foreign) anions reversibly increased Cl-dependent K efflux and Rb influx,…”
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Oxidative activation of K-Cl cotransport by diamide in erythrocytes from humans with red cell disorders, and from several other mammalian species by Adragna, N C, Lauf, P K

“…Red blood cells (RBCs) from different mammalian species were investigated for the presence of diamide-induced oxidative activation of K-Cl cotransport reported…”
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Kinetics of DIDS inhibition of swelling-activated K-Cl cotransport in low K sheep erythrocytes by DELPIRE, E, LAUF, P. K

“…The inhibitory effect of various stilbene disulfonates was examined on the swelling-activated Cl-dependent K transport (K-Cl cotransport) in low K sheep…”
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Passive K+-Cl- fluxes in low-K+ sheep erythrocytes: modulation by A23187 and bivalent cations by Lauf, P K

“…A fraction of the ouabain-resistant (OR) K+ flux of low-K+ (LK) sheep erythrocytes is Cl- dependent (K+-Cl- transport) and is activated reversibly by cell…”
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