Search Results - "Laudermilk, Lucas T."

NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells by Paugh, Steven W, Bonten, Erik J, Savic, Daniel, Ramsey, Laura B, Thierfelder, William E, Gurung, Prajwal, Malireddi, R K Subbarao, Actis, Marcelo, Mayasundari, Anand, Min, Jaeki, Coss, David R, Laudermilk, Lucas T, Panetta, John C, McCorkle, J Robert, Fan, Yiping, Crews, Kristine R, Stocco, Gabriele, Wilkinson, Mark R, Ferreira, Antonio M, Cheng, Cheng, Yang, Wenjian, Karol, Seth E, Fernandez, Christian A, Diouf, Barthelemy, Smith, Colton, Hicks, J Kevin, Zanut, Alessandra, Giordanengo, Audrey, Crona, Daniel, Bianchi, Joy J, Holmfeldt, Linda, Mullighan, Charles G, den Boer, Monique L, Pieters, Rob, Jeha, Sima, Dunwell, Thomas L, Latif, Farida, Bhojwani, Deepa, Carroll, William L, Pui, Ching-Hon, Myers, Richard M, Guy, R Kiplin, Kanneganti, Thirumala-Devi, Relling, Mary V, Evans, William E

“…William Evans and colleagues find that the proinflammatory genes CASP1 and NLRP3 are expressed at higher levels in primary acute lymphoblastic leukemia cells…”
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The Monoacylglycerol Lipase Inhibitor ABX-1431 Does Not Improve Alcoholic Liver Disease by Lucitti, Jennifer L, Laudermilk, Lucas T, Amato, George S, Maitra, Rangan

“…Excessive alcohol consumption can result in alcoholic liver disease (ALD). There is no FDA-approved drug to specifically treat ALD and current management…”
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MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression by Paugh, Steven W, Coss, David R, Bao, Ju, Laudermilk, Lucas T, Grace, Christy R, Ferreira, Antonio M, Waddell, M Brett, Ridout, Granger, Naeve, Deanna, Leuze, Michael, LoCascio, Philip F, Panetta, John C, Wilkinson, Mark R, Pui, Ching-Hon, Naeve, Clayton W, Uberbacher, Edward C, Bonten, Erik J, Evans, William E

“…MicroRNAs are important regulators of gene expression, acting primarily by binding to sequence-specific locations on already transcribed messenger RNAs (mRNA)…”
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Differential Regulation of Zfp30 Expression in Murine Airway Epithelia Through Altered Binding of ZFP148 to rs51434084 by Laudermilk, Lucas T, Thomas, Joseph M, Kelada, Samir N

“…Neutrophil chemotaxis to the airways is a key aspect of host response to microbes and a feature of multiple pulmonary diseases including asthma. Tight…”
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Δ9-Tetrahydrocannabinol Effects on Respiration and Heart Rate Across Route of Administration in Female and Male Mice by Laudermilk, Lucas T., Marusich, Julie A., Wiley, Jenny L.

“…The physiological impact of cannabinoid receptor agonists is of great public health interest due to their increased use in recreational and therapeutic…”
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Aplnr knockout mice display sex-specific changes in conditioned fear by Laudermilk, Lucas T., Harper, Kathryn M., Moy, Sheryl S., Runyon, Scott, Zhou, Bin, Koller, Beverly, Maitra, Rangan

“…The G-protein-coupled receptor APLNR and its ligands apelin and ELABELA/TODDLER/apela comprise the apelinergic system, a signaling pathway that is critical…”
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Novel Peripherally Selective Cannabinoid Receptor 1 Neutral Antagonist Improves Metabolic Dysfunction-Associated Steatotic Liver Disease in Mice by Laudermilk, Lucas T., Schlosburg, Joel E., Gay, Elaine A., Decker, Ann M., Williams, Aaron, Runton, Rubica, Vasukuttan, Vineetha, Kotiya, Archana, Amato, George S., Maitra, Rangan

“…The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) is increasing globally. MASLD is characterized by clinically significant…”
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Baseline and innate immune response characterization of a Zfp30 knockout mouse strain by Laudermilk, Lucas T., Tovar, Adelaide, Homstad, Alison K., Thomas, Joseph M., McFadden, Kathryn M., Tune, Miriya K., Cowley, Dale O., Mock, Jason R., Ideraabdullah, Folami, Kelada, Samir N. P.

“…Airway neutrophilia is correlated with disease severity in a number of chronic and acute pulmonary diseases, and dysregulation of neutrophil chemotaxis can…”
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MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression: e1004744 by Paugh, Steven W, Coss, David R, Bao, Ju, Laudermilk, Lucas T, Grace, Christy R, Ferreira, Antonio M, Waddell, M Brett, Ridout, Granger, Naeve, Deanna, Leuze, Michael, LoCascio, Philip F, Panetta, John C, Wilkinson, Mark R, Pui, Ching-Hon, Naeve, Clayton W, Uberbacher, Edward C, Bonten, Erik J, Evans, William E

“…MicroRNAs are important regulators of gene expression, acting primarily by binding to sequence-specific locations on already transcribed messenger RNAs (mRNA)…”
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NALP3 inflammasome up-regulation and CASP1 cleavage of the glucocorticoid receptor causes glucocorticoid resistance in leukemia cells by Paugh, Steven W., Bonten, Erik J., Savic, Daniel, Ramsey, Laura B., Thierfelder, William E., Gurung, Prajwal, Malireddi, R. K. Subbarao, Actis, Marcelo, Mayasundari, Anand, Min, Jaeki, Coss, David R., Laudermilk, Lucas T., Panetta, John C., McCorkle, J. Robert, Fan, Yiping, Crews, Kristine R., Stocco, Gabriele, Wilkinson, Mark R., Ferreira, Antonio M., Cheng, Cheng, Yang, Wenjian, Karol, Seth E., Fernandez, Christian A., Diouf, Barthelemy, Smith, Colton, Hicks, J. Kevin, Zanut, Alessandra, Giordanengo, Audrey, Crona, Daniel, Bianchi, Joy J., Holmfeldt, Linda, Mullighan, Charles G., den Boer, Monique L., Pieters, Rob, Jeha, Sima, Dunwell, Thomas L., Latif, Farida, Bhojwani, Deepa, Carroll, William L., Pui, Ching-Hon, Myers, Richard M., Guy, R. Kiplin, Kanneganti, Thirumala-Devi, Relling, Mary V., Evans, William E.

“…Glucocorticoids are universally used in the treatment of acute lymphoblastic leukemia (ALL), and leukemia cell resistant to glucocorticoids confers a poor…”
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