Search Results - "Laube, Britta"
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Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis
Published in Proceedings of the National Academy of Sciences - PNAS (25-05-2010)“…Systemic lupus erythematosus (SLE) is an autoimmune disease in which patients develop autoantibodies to DNA, histones, and often to neutrophil proteins. These…”
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Neutrophil extracellular traps: how to generate and visualize them
Published in Journal of visualized experiments (24-02-2010)“…Neutrophil granulocytes are the most abundant group of leukocytes in the peripheral blood. As professional phagocytes, they engulf bacteria and kill them…”
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Mouse Neutrophil Extracellular Traps in Microbial Infections
Published in Journal of innate immunity (01-01-2009)“…Neutrophil extracellular traps (NETs) play an important role in innate immunity to microbial infections. NETs have been described in several species, but the…”
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Prevalence of Propionibacterium acnes in diseased prostates and its inflammatory and transforming activity on prostate epithelial cells
Published in International journal of medical microbiology (01-01-2011)“…Abstract Prostate cancer (PCa) is the second leading cause of male cancer deaths in the Western world. Mounting evidence has revealed that chronic inflammation…”
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The common structural architecture of Shigella flexneri and Salmonella typhimurium type three secretion needles
Published in PLoS pathogens (01-03-2013)“…The Type Three Secretion System (T3SS), or injectisome, is a macromolecular infection machinery present in many pathogenic Gram-negative bacteria. It consists…”
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Protein refolding is required for assembly of the type three secretion needle
Published in Nature structural & molecular biology (01-07-2010)“…Type three secretion systems consist of a multisubunit protein complex that crosses the bacterial membranes and an extracellular needle-shaped structure. New…”
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Enzyme induction in cryopreserved human hepatocyte cultures
Published in Toxicology (Amsterdam) (15-03-2006)“…Freshly isolated human hepatocytes are considered as the gold standard for in vitro testing of drug candidates. Meanwhile also cryopreserved human hepatocyte…”
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Human relevance of follicular thyroid tumors in rodents caused by non-genotoxic substances
Published in Regulatory toxicology and pharmacology (01-10-2018)“…Chronic stimulation of the thyroid gland of rodents by TSH leads to thyroid follicular hyperplasia and subsequently to thyroid follicular adenomas and…”
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Classification or non-classification of substances with positive tumor findings in animal studies: Guidance by the German MAK commission
Published in Regulatory toxicology and pharmacology (01-11-2019)“…One of the important tasks of the German Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (known as the MAK…”
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Propionibacterium acnes host cell tropism contributes to vimentin‐mediated invasion and induction of inflammation
Published in Cellular microbiology (01-11-2012)“…Summary The contribution of the human microbiota to health and disease is poorly understood. Propionibacterium acnes is a prominent member of the skin…”
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The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles: e1003245
Published in PLoS pathogens (01-03-2013)“…The Type Three Secretion System (T3SS), or injectisome, is a macromolecular infection machinery present in many pathogenic Gram-negative bacteria. It consists…”
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New Hepatocyte In Vitro Systems for Drug Metabolism: Metabolic Capacity and Recommendations for Application in Basic Research and Drug Development, Standard Operation Procedures
Published in Drug metabolism reviews (01-01-2003)“…Primary hepatocytes represent a well-accepted in vitro cell culture system for studies of drug metabolism, enzyme induction, transplantation, viral hepatitis,…”
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Neutrophil Extracellular Traps: How to Generate and Visualize Them
Published in Journal of visualized experiments (24-02-2010)Get full text
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Determination of Testosterone Metabolites in Rat Hepatocytes with and without Cryopreservation by On-Line SPE Column-Switching LC and MS Detection
Published in Chromatographia (2008)“…In a recently published paper development of a sensitive automated “on-line” solid-phase extraction (SPE)/RP-HPLC assay for 6β-hydroxytestosterone (6β-OHT)…”
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Migration of Human Glioma Cells on Myelin
Published in Neurosurgery (01-04-1996)Get full text
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Expression of Opioid Receptor Subtypes and Their Ligands in Fibrillating Human Atria
Published in Pacing and clinical electrophysiology (01-01-2005)“…The δ‐ and κ‐receptor subtypes are both abundantly expressed in the human heart and participate in age‐ and stress‐related alterations of cardiac function…”
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Glioma cell adhesion and migration on human brain sections
Published in Anticancer research (01-07-1998)“…Within the brain, dissemination of glioma cells follows myelinated fiber tracts and extracellular matrix containing structures such as the basement membranes…”
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Migration of human glioma cells on myelin
Published in Neurosurgery (01-04-1996)“…Histoanatomically invading astrocytoma cells appear to migrate along distinct structures within the brain. Astrocytoma invasion may occur along extracellular…”
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