Search Results - "Laub, O"

Fine‐mapping of IgE‐associated loci 1q23, 5q31, and 12q13 using 1000 Genomes Project data by Sharma, V., Michel, S., Gaertner, V., Franke, A., Vogelberg, C., Berg, A., Bufe, A., Heinzmann, A., Laub, O., Rietschel, E., Simma, B., Frischer, T., Genuneit, J., Zeilinger, S., Illig, T., Schedel, M., Potaczek, D. P., Kabesch, M.

“…Background Genome‐wide association studies (GWAS) repeatedly identified 1q23 (FCER1A), 5q31 (RAD50‐IL13 and IL4), and 12q13 (STAT6) as major susceptibility…”
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Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact by Toncheva, A. A., Potaczek, D. P., Schedel, M., Gersting, S. W., Michel, S., Krajnov, N., Gaertner, V. D., Klingbeil, J. M., Illig, T., Franke, A., Winkler, C., Hohlfeld, J. M., Vogelberg, C., Berg, A., Bufe, A., Heinzmann, A., Laub, O., Rietschel, E., Simma, B., Genuneit, J., Muntau, A. C., Kabesch, M.

“…Background Genomewide association studies identified ORMDL3 as a plausible asthma candidate gene. ORMDL proteins regulate sphingolipid metabolism and ceramide…”
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A role of FCER1A and FCER2 polymorphisms in IgE regulation by Sharma, V., Michel, S., Gaertner, V., Franke, A., Vogelberg, C., Berg, A., Bufe, A., Heinzmann, A., Laub, O., Rietschel, E., Simma, B., Frischer, T., Genuneit, J., Potaczek, D. P., Kabesch, M.

“…Background Both FCER2 and FCER1A encode subunits of IgE receptors. Variants in FCER1A were previously identified as major determinants of IgE levels in…”
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Polymorphisms in the IRF-4 gene, asthma and recurrent bronchitis in children by Pinto, L. A., Michel, S., Klopp, N., Vogelberg, C., von Berg, A., Bufe, A., Heinzmann, A., Laub, O., Simma, B., Frischer, T., Genuneit, J., Gorski, M., Illig, T., Kabesch, M.

“…Summary Background Interferon‐regulatory factors (IRFs) play a crucial role in immunity, not only influencing interferon expression but also T cell…”
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Hepatitis B Virus Gene Function: The Precore Region Targets the Core Antigen to Cellular Membranes and Causes the Secretion of the e Antigen by Ou, Jing-Hsiung, Laub, Orgad, Rutter, William J.

“…The core gene of the hepatitis B virus genome contains two conserved in-phase initiation codons separated by about 90 nucleotides. This region (``the precore…”
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Liver-specific expression of hepatitis B virus is determined by the combined action of the core gene promoter and the enhancer by HONIGWACHS, J, FAKTOR, O, DIKSTEIN, R, SHAUL, Y, LAUB, O

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Identification of a promoter element located upstream from the hepatitis B virus X gene by TREININ, M, LAUB, O

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A human hepatitis B viral enhancer element by Shaul, Y., Rutter, W.J., Laub, O.

“…Fragments of the cloned hepatitis B virus (HBV) genome were assayed in vivo for the presence of a transcriptional enhancer element. We demonstrate that…”
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The hepatitis B virus-associated reverse transcriptase is encoded by the viral pol gene by BAVAND, M, FEITELSON, M, LAUB, O

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Two proteins with reverse transcriptase activities associated with hepatitis B virus-like particles by BAVAND, M. R, LAUB, O

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Nocturnal asthma is affected by genetic interactions between RORA and NPSR1 by Gaertner, Vincent D., Michel, Sven, Curtin, John A., Pulkkinen, Ville, Acevedo, Nathalie, Söderhäll, Cilla, Berg, Andrea, Bufe, Albrecht, Laub, Otto, Rietschel, Ernst, Heinzmann, Andrea, Simma, Burkhard, Vogelberg, Christian, Pershagen, Göran, Melén, Erik, Simpson, Angela, Custovic, Adnan, Kere, Juha, Kabesch, Michael

“…Background Neuropeptide S Receptor 1 ( NPSR1) and Retinoid Acid Receptor‐Related Orphan Receptor Alpha (RORA ) interact biologically, are both known candidate…”
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Expression of the human insulin gene and cDNA in a heterologous mammalian system by Laub, O, Rutter, W J

“…The human insulin gene or the corresponding cDNA has been inserted into the early region of a simian virus 40 vector in which all SV40 splice junctions were…”
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Transcription of hepatitis B virus by RNA polymerase II by RALL, L. B, STANDRING, B. N, LAUB, O, RUTTER, W. J

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Doublesex and mab-3 related transcription factor 1 ( DMRT1 ) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages by Schieck, Maximilian, PhD, Schouten, Jan P., MSc, Michel, Sven, PhD, Suttner, Kathrin, PhD, Toncheva, Antoaneta A., PhD, Gaertner, Vincent D., BSc, Illig, Thomas, PhD, Lipinski, Simone, PhD, Franke, Andre, PhD, Klintschar, Michael, MD, Kalayci, Omer, MD, Sahiner, Umit M., MD, Birben, Esra, PhD, Melén, Erik, MD, Pershagen, Göran, MD, PhD, Freidin, Maxim B., PhD, Ogorodova, Ludmila M., MD, PhD, DSc, Granell, Raquel, PhD, Henderson, John, MD, PhD, Brunekreef, Bert, PhD, Smit, Henriëtte A., PhD, Vogelberg, Christian, MD, von Berg, Andrea, MD, Bufe, Albrecht, MD, Heinzmann, Andrea, MD, Laub, Otto, MD, Rietschel, Ernst, MD, Simma, Burkhard, MD, Genuneit, Jon, MD, Jonigk, Danny, MD, Postma, Dirkje S., MD, PhD, Koppelman, Gerard H., MD, PhD, Vonk, Judith M., PhD, Timens, Wim, MD, PhD, Boezen, H. Marike, PhD, Kabesch, Michael, MD

“…Background Asthma is a disease affecting more boys than girls in childhood and more women than men in adulthood. The mechanisms behind these sex-specific…”
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B35 GENETICS OF LUNG DISEASE: The Role Of Cyp11a1 Polymorphisms In Asthma Susceptibility by Schedel, M, Michel, S, Franke, A, Von Berg, A, Bufe, A, Rietschel, E, Heinzmann, A, Laub, O, Simma, B, Frischer, T, Genuneit, J, Kabesch, M, Gelfand, E

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Alpha interferon suppresses hepatitis B virus enhancer activity and reduces viral gene transcription by RAN TUR-KASPA, TEICHER, L, LAUB, O, ITIN, A, DAGAN, D, BLOOM, B. R, SHAFRITZ, D. A

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Synthesis of hepatitis B surface antigen in mammalian cells: expression of the entire gene and the coding region by LAUB, O, RALL, L. B, TRUETT, M, SHAUL, Y, STANDRING, D. N, VALENZUELA, P, RUTTER, W. J

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A21 GENETIC REGULATION OF CHRONIC AIRWAY INFLAMMATION: Asthma-Associated Ormdl3 Polymorphisms Alter Transcription Factor Binding, Promoter Activity And Ormdl3 Gene Expression by Schedel, M, Michel, S, Gaertner, V D, Toncheva, A A, Depner, M, Binia, A, Schieck, M, Rieger, M T, Klopp, N, Bufe, A, Laub, O, Berg, A Von, Rietschel, E, Heinzmann, A, Simma, B, Vogelberg, C, Genuneit, J, Illig, T, Kabesch, M

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5,6-Dichloro-1-β -Ribofuranosylbenzimidazole Enhances Premature Termination of Late Transcription of Simian Virus 40 DNA by Laub, Orgad, Jakobovits, Edward B., Aloni, Yosef

“…Short RNA chains initiating at the major promoter sites for simian virus 40 (SV40) late transcription are elongated to approximately 450 nucleotides in a molar…”
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Novel Mechanism for RNA Maturation: The Leader Sequences of Simian Virus 40 mRNA are not Transcribed Adjacent to the Coding Sequences by Aloni, Yosef, Dhar, Ravi, Laub, Orgad, Horowitz, Mia, Khoury, George

“…The 5′-terminal 100-200 ribonucleotides of late simian virus 40 (SV40) mRNAs are not transcribed immediately adjacent to their coding sequences. This…”
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