Search Results - "Lau, Y S"
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Characterizing superspreading events and age-specific infectiousness of SARS-CoV-2 transmission in Georgia, USA
Published in Proceedings of the National Academy of Sciences - PNAS (08-09-2020)“…It is imperative to advance our understanding of heterogeneities in the transmission of SARS-CoV-2 such as age-specific infectiousness and superspreading. To…”
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Comparing and linking machine learning and semi-mechanistic models for the predictability of endemic measles dynamics
Published in PLoS computational biology (01-09-2022)“…Measles is one the best-documented and most-mechanistically-studied non-linear infectious disease dynamical systems. However, systematic investigation into the…”
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Transmission network reconstruction for foot-and-mouth disease outbreaks incorporating farm-level covariates
Published in PloS one (15-07-2020)“…Transmission network modelling to infer 'who infected whom' in infectious disease outbreaks is a highly active area of research. Outbreaks of foot-and-mouth…”
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Conversational agents in healthcare: a systematic review
Published in Journal of the American Medical Informatics Association : JAMIA (01-09-2018)“…Our objective was to review the characteristics, current applications, and evaluation measures of conversational agents with unconstrained natural language…”
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Genetic drift and purifying selection shape within-host influenza A virus populations during natural swine infections
Published in PLoS pathogens (01-04-2024)“…Patterns of within-host influenza A virus (IAV) diversity and evolution have been described in natural human infections, but these patterns remain poorly…”
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Rectified Latent Variable Model-Based EMG Factorization of Inhibitory Muscle Synergy Components Related to Aging, Expertise and Force-Tempo Variations
Published in Sensors (Basel, Switzerland) (01-05-2024)“…Muscle synergy has been widely acknowledged as a possible strategy of neuromotor control, but current research has ignored the potential inhibitory components…”
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Post-lockdown changes of age-specific susceptibility and its correlation with adherence to social distancing measures
Published in Scientific reports (17-03-2022)“…Social distancing measures are effective in reducing overall community transmission but much remains unknown about how they have impacted finer-scale dynamics…”
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Ethical Issues of Social Media Usage in Healthcare
Published in Yearbook of medical informatics (13-08-2015)“…Objective: Social media, web and mobile technologies are increasingly used in healthcare and directly support patientcentered care. Patients benefit from…”
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Unreported cases in the 2014-2016 Ebola epidemic: Spatiotemporal variation, and implications for estimating transmission
Published in PLoS neglected tropical diseases (01-01-2018)“…In the recent 2014-2016 Ebola epidemic in West Africa, non-hospitalized cases were an important component of the chain of transmission. However,…”
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A mechanistic spatio-temporal framework for modelling individual-to-individual transmission-With an application to the 2014-2015 West Africa Ebola outbreak
Published in PLoS computational biology (01-10-2017)“…In recent years there has been growing availability of individual-level spatio-temporal disease data, particularly due to the use of modern communicating…”
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Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment
Published in Neuroscience (01-01-2001)“…1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is widely used to induce an animal model of Parkinsonism. The conventional mouse model, which usually…”
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12
Effect of androgen deprivation therapy on cardiovascular function in Chinese patients with advanced prostate cancer: a prospective cohort study
Published in Scientific reports (22-10-2020)“…Androgen deprivation therapy (ADT) is the standard treatment for advanced prostate cancer, but its effect on cardiovascular and metabolic function in Asian…”
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Spatial and temporal dynamics of superspreading events in the 2014–2015 West Africa Ebola epidemic
Published in Proceedings of the National Academy of Sciences - PNAS (28-02-2017)“…The unprecedented scale of the Ebola outbreak in Western Africa (2014–2015) has prompted an explosion of efforts to understand the transmission dynamics of the…”
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14
Effects of Panax ginseng on tumor necrosis factor-α-mediated inflammation: a mini-review
Published in Molecules (Basel, Switzerland) (30-03-2011)“…Panax ginseng is one of the most commonly used Chinese medicines in China, Asia and Western countries. The beneficial effects of ginseng have been attributed…”
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Scientific Basis of Botanical Medicine as Alternative Remedies for Rheumatoid Arthritis
Published in Clinical reviews in allergy & immunology (01-06-2013)“…Rheumatoid arthritis (RA) is a chronic, systemic autoimmune inflammatory disorder that causes permanent disability and mortality to approximately 1 to 100…”
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Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model of Parkinson’s disease
Published in Neuroscience (01-01-2006)“…Parkinson’s disease is associated with a progressive loss of substantia nigra pars compacta dopaminergic neurons. The cellular and molecular mechanisms…”
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Model diagnostics and refinement for phylodynamic models
Published in PLoS computational biology (01-04-2019)“…Phylodynamic modelling, which studies the joint dynamics of epidemiological and evolutionary processes, has made significant progress in recent years due to…”
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Evaluation of rapid antigen test for detection of SARS-CoV-2 virus
Published in Journal of clinical virology (01-08-2020)“…•The rapid diagnosis of COVID-19 patients is essential to reduce the disease spread.•The detection limits between rapid antigen detection (RAD) test, viral…”
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Glycoprotein M is important for the efficient incorporation of glycoprotein H–L into herpes simplex virus type 1 particles
Published in Journal of general virology (01-02-2012)“…Herpes simplex virus type 1 glycoprotein M (gM) is a type III membrane protein conserved throughout the family HERPESVIRIDAE: However, despite this…”
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Acceptability, motivation and the prospect of cure for people living with HIV and their healthcare providers in HIV cure-focused treatment interruption studies
Published in AIDS research and therapy (10-11-2020)“…Analytical treatment interruptions (ATI) are commonly used clinical endpoints to assess interventions aimed at curing HIV or achieving antiretroviral therapy…”
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