Search Results - "Lau, Rachel"

Effectiveness of overuse injury prevention programs on upper extremity performance in overhead youth athletes: A systematic review by Lau, Rachel Y., Mukherjee, Swarup

“…Several targeted upper extremity injury prevention programs have been developed to mitigate the risk of upper extremity overuse injuries among youth athletes…”
Get full text

Novel detection of Leishmania RNA virus-1 (LRV-1) in clinical isolates of Leishmania Viannia panamensis by Kariyawasam, Ruwandi, Lau, Rachel, Valencia, Braulio M., Llanos-Cuentas, Alejandro, Boggild, Andrea K.

“…American tegumentary leishmaniasis comprises a discrete set of clinical presentations endemic to Latin America. Leishmania RNA virus-1 (LRV-1) is a…”
Get full text

Phosphoproteomic profiling of early rheumatoid arthritis synovium reveals active signalling pathways and differentiates inflammatory pathotypes by Çubuk, Cankut, Lau, Rachel, Cutillas, Pedro, Rajeeve, Vinothini, John, Christopher R, Surace, Anna E A, Hands, Rebecca, Fossati-Jimack, Liliane, Lewis, Myles J, Pitzalis, Costantino

“…Kinases are intracellular signalling mediators and key to sustaining the inflammatory process in rheumatoid arthritis (RA). Oral inhibitors of Janus Kinase…”
Get full text

Leishmania RNA Virus 1 (LRV-1) in Leishmania ( Viannia ) braziliensis Isolates from Peru: A Description of Demographic and Clinical Correlates by Kariyawasam, Ruwandi, Lau, Rachel, Valencia, Braulio M, Llanos-Cuentas, Alejandro, Boggild, Andrea K

“…RNA virus 1-1 (LRV-1-1) is a dsRNA virus identified in isolates of ( ) and thought to advance localized cutaneous leishmaniasis (LCL) to mucocutaneous or…”
Get full text

Molecular characterization of Cryptosporidium isolates from humans in Ontario, Canada by Guy, Rebecca A, Yanta, Christine A, Muchaal, Pia K, Rankin, Marisa A, Thivierge, Karine, Lau, Rachel, Boggild, Andrea K

“…Cryptosporidiosis is a gastrointestinal disease with global distribution. It has been a reportable disease in Canada since 2000; however, routine molecular…”
Get full text

Susceptibility testing of Leishmania spp. against amphotericin B and fluconazole using the Sensititre™ YeastOne™ YO9 platform by Kariyawasam, Ruwandi, Challa, Priyanka, Lau, Rachel, Boggild, Andrea K

“…Current drug regimens for cutaneous leishmaniasis (CL) include toxic systemic therapies such as amphotericin B (AB) and pentavalent antimonials. Fluconazole…”
Get full text

Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis by Nerviani, Alessandra, Boutet, Marie-Astrid, Ghirardi, Giulia Maria, Goldmann, Katriona, Sciacca, Elisabetta, Rivellese, Felice, Pontarini, Elena, Prediletto, Edoardo, Abatecola, Federico, Caliste, Mattia, Pagani, Sara, Mauro, Daniele, Bellan, Mattia, Cubuk, Cankut, Lau, Rachel, Church, Sarah E., Hudson, Briana M., Humby, Frances, Bombardieri, Michele, Lewis, Myles J., Pitzalis, Costantino

“…The TAM tyrosine kinases, Axl and MerTK, play an important role in rheumatoid arthritis (RA). Here, using a unique synovial tissue bioresource of patients with…”
Get full text

Molecular Surveillance for Imported Antimicrobial Resistant Plasmodium falciparum, Ontario, Canada by Kariyawasam, Ruwandi, Lau, Rachel, Shao, Eric, Tan, Katherine, Showler, Adrienne, Ralevski, Filip, Patel, Samir N, Boggild, Andrea K

“…Single-nucleotide polymorphisms at several loci have been correlated with Plasmodium falciparum drug resistance. We examined the prevalence of resistance…”
Get full text

Leishmania RNA virus-1 is similarly detected among metastatic and non-metastatic phenotypes in a prospective cohort of American Tegumentary Leishmaniasis by Valencia, Braulio Mark, Lau, Rachel, Kariyawasam, Ruwandi, Jara, Marlene, Ramos, Ana Pilar, Chantry, Mathilde, Lana, Justin T, Boggild, Andrea K, Llanos-Cuentas, Alejandro

“…American Tegumentary Leishmaniasis (ATL) is an endemic and neglected disease of South America. Here, mucosal leishmaniasis (ML) disproportionately affects up…”
Get full text

Deadly disasters in southeastern South America: flash floods and landslides of February 2022 in Petrópolis, Rio de Janeiro by Alcântara, Enner, Marengo, José A, Mantovani, José, Londe, Luciana R, San, Rachel Lau Yu, Park, Edward, Lin, Yunung Nina, Wang, Jingyu, Mendes, Tatiana, Cunha, Ana Paula, Pampuch, Luana, Seluchi, Marcelo, Simões, Silvio, Cuartas, Luz Adriana, Goncalves, Demerval, Massi, Klécia, Alvalá, Regina, Moraes, Osvaldo, Filho, Carlos Souza, Mendes, Rodolfo, Nobre, Carlos

“…On 15 February 2022, the city of Petrópolis in the highlands of the state of Rio de Janeiro, Brazil, received an unusually high volume of rain within 3 h (258…”
Get full text

Multiplex real-time quantitative PCR, microscopy and rapid diagnostic immuno-chromatographic tests for the detection of Plasmodium spp: performance, limit of detection analysis and quality assurance by Khairnar, Krishna, Martin, Donald, Lau, Rachel, Ralevski, Filip, Pillai, Dylan R

“…Accurate laboratory diagnosis of malaria species in returning travelers is paramount in the treatment of this potentially fatal infectious disease. A total of…”
Get full text

Genome-wide dissection of globally emergent multi-drug resistant serotype 19A Streptococcus pneumoniae by Pillai, Dylan R, Shahinas, Dea, Buzina, Alla, Pollock, Remy A, Lau, Rachel, Khairnar, Krishna, Wong, Andrew, Farrell, David J, Green, Karen, McGeer, Allison, Low, Donald E

“…Emergence of multi-drug resistant (MDR) serotype 19A Streptococcus pneumoniae (SPN) is well-documented but causal factors remain unclear. Canadian SPN isolates…”
Get full text

Virulence factor RNA transcript expression in the Leishmania Viannia subgenus: influence of species, isolate source, and Leishmania RNA virus-1 by Kariyawasam, Ruwandi, Mukkala, Avinash N, Lau, Rachel, Valencia, Braulio M, Llanos-Cuentas, Alejandro, Boggild, Andrea K

“…RNA virus-1 (LRV1) is a double-stranded RNA virus identified in 20-25% of -species endemic to Latin America, and is believed to accelerate cutaneous to mucosal…”
Get full text

Spectrum of bacterial pathogens in inflammatory and noninflammatory cutaneous ulcers of American tegumentary leishmaniasis by Kariyawasam, Ruwandi, Gascon, Bryan, Challa, Priyanka, Mah, Jordan, Lau, Rachel, Valencia, Braulio M., Llanos-Cuentas, Alejandro, Boggild, Andrea K.

“…Background: Cutaneous leishmaniasis (CL) ulcers exhibiting an inflammatory phenotype, characterized by purulent exudate, erythema, pain, and/or lymphatic…”
Get full text

Surveillance of Amoebic Keratitis-Causing Acanthamoebae for Potential Bacterial Endosymbionts in Ontario, Canada by Karsenti, Nessika, Purssell, Andrew, Lau, Rachel, Ralevski, Filip, Bhasker, Shveta, Raheel, Hira, Boggild, Andrea K.

“…Acanthamoeba spp. are the causative pathogens of several infections, including amoebic keratitis (AK), a vision-threatening infection. Acanthamoebae from…”
Get full text

Development and validation of a real-time PCR assay for the detection of clinical acanthamoebae by Karsenti, Nessika, Lau, Rachel, Purssell, Andrew, Chong-Kit, Ann, Cunanan, Marlou, Gasgas, Jason, Tian, Jinfang, Wang, Amanda, Ralevski, Filip, Boggild, Andrea K

“…Suboptimal agreement between molecular assays for the detection of Acanthamoeba spp. in clinical specimens has been demonstrated, and poor assay sensitivity…”
Get full text

Performance characteristics of diagnostic assays for schistosomiasis in Ontario, Canada by Lau, Rachel, Makhani, Leila, Omoruna, Osaru, Lecce, Celine, Shao, Eric, Cunanan, Marlou, Ralevski, Filip, Cheema, Karamjit, Boggild, Andrea K.

“…Introduction: Due to lower intensity of infection and greater intervals from last exposure, parasitologic detection methods for schistosomiasis are poorly…”
Get full text

Spectrum of Viral Pathogens in Blood of Malaria-Free Ill Travelers Returning to Canada by Kariyawasam, Ruwandi, Lau, Rachel, Eshaghi, Alireza, Patel, Samir N, Sider, Doug, Gubbay, Jonathan B, Boggild, Andrea K

“…Malaria is the most common specific cause of fever in returning travelers, but many other vectorborne infections and viral infections are emerging and…”
Get full text

CTCF cis-regulates trinucleotide repeat instability in an epigenetic manner: a novel basis for mutational hot spot determination by Libby, Randell T, Hagerman, Katharine A, Pineda, Victor V, Lau, Rachel, Cho, Diane H, Baccam, Sandy L, Axford, Michelle M, Cleary, John D, Moore, James M, Sopher, Bryce L, Tapscott, Stephen J, Filippova, Galina N, Pearson, Christopher E, La Spada, Albert R

“…At least 25 inherited disorders in humans result from microsatellite repeat expansion. Dramatic variation in repeat instability occurs at different disease…”
Get full text

Artesunate misuse and Plasmodium falciparum malaria in traveler returning from Africa by Shahinas, Dea, Lau, Rachel, Khairnar, Krishna, Hancock, David, Pillai, Dylan R

“…Plasmodium falciparum malaria developed in an African-born traveler who returned to Canada after visiting Nigeria. While there, she took artesunate…”
Get full text