Search Results - "Lau, Peter"
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A Novel Actinobacterial Cutinase Containing a Noncatalytic Polymer-Binding Domain
Published in Applied and environmental microbiology (11-01-2022)“…The single putative cutinase-encoding gene from the genome of Kineococcus radiotolerans SRS30216 was cloned and expressed in Escherichia coli as a secreted…”
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2
Substrate profiling of cyclohexylamine oxidase and its mutants reveals new biocatalytic potential in deracemization of racemic amines
Published in Applied microbiology and biotechnology (01-02-2014)“…A cyclohexylamine oxidase (CHAO) of bacterial origin was previously shown to be a potentially useful catalyst in the deracemization of racemic primary amines…”
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3
A closer look at immune-mediated myocarditis in the era of combined checkpoint blockade and targeted therapies
Published in European journal of cancer (1990) (01-01-2020)“…Immune checkpoint inhibitors (ICI) and tyrosine kinase inhibitors (TKI) have transformed the management of many malignancies. Although rare, immune-mediated…”
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4
Tissue-Dependent Tumor Microenvironments and Their Impact on Immunotherapy Responses
Published in Frontiers in immunology (31-01-2018)“…Recent advances in cancer immunology have led to a better understanding of the role of the tumor microenvironment (TME) in tumor initiation, progression, and…”
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FDG PET/CT for tumoral and systemic immune response monitoring of advanced melanoma during first-line combination ipilimumab and nivolumab treatment
Published in European journal of nuclear medicine and molecular imaging (01-11-2020)“…Purpose We aimed to investigate the role of FDG-PET/CT in monitoring of response and immune-related adverse events (irAEs) following first-line…”
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A Case Study on Research Postgraduate Students’ Understanding of Academic Integrity at a Hong Kong University
Published in Frontiers in education (Lausanne) (09-04-2021)“…This case study aims to understand how research postgraduate (RPg) students at a Hong Kong university perceive academic integrity before and after…”
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Cloning and characterization of the first GH10 and GH11 xylanases from Rhizopus oryzae
Published in Applied microbiology and biotechnology (01-10-2014)“…The only available genome sequence for Rhizopus oryzae strain 99-880 was annotated to not encode any β-1,4-endoxylanase encoding genes of the glycoside…”
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Camphor Pathway Redux: Functional Recombinant Expression of 2,5- and 3,6-Diketocamphane Monooxygenases of Pseudomonas putida ATCC 17453 with Their Cognate Flavin Reductase Catalyzing Baeyer-Villiger Reactions
Published in Applied and Environmental Microbiology (01-05-2013)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Identification and characterization of a chc gene cluster responsible for the aromatization pathway of cyclohexanecarboxylate degradation in Sinomonas cyclohexanicum ATCC 51369
Published in Journal of bioscience and bioengineering (01-12-2021)“…Cyclohexanecarboxylate (CHCA) is formed by oxidative microbial degradation of n-alkylcycloparaffins and anaerobic degradation of benzoate, and also known to be…”
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Differential Lipopolysaccharide Core Capping Leads to Quantitative and Correlated Modifications of Mechanical and Structural Properties in Pseudomonas aeruginosa Biofilms
Published in Journal of Bacteriology (01-11-2009)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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11
Baeyer−Villiger Monooxygenases: More Than Just Green Chemistry
Published in Chemical reviews (13-07-2011)Get full text
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12
Activation of Canonical BMP4-SMAD7 Signaling Suppresses Breast Cancer Metastasis
Published in Cancer research (Chicago, Ill.) (15-03-2020)“…Metastasis is the major cause of death in patients with cancer; with no therapeutic cure, treatments remain largely palliative. As such, new targets and…”
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13
Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Published in Cochrane database of systematic reviews (26-05-2021)“…Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptor-negative metastatic…”
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The Substrate-Bound Crystal Structure of a Baeyer–Villiger Monooxygenase Exhibits a Criegee-like Conformation
Published in Journal of the American Chemical Society (09-05-2012)“…The Baeyer–Villiger monooxygenases (BVMOs) are a family of bacterial flavoproteins that catalyze the synthetically useful Baeyer–Villiger oxidation reaction…”
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15
Absolute Quantitation of Bacterial Biofilm Adhesion and Viscoelasticity by Microbead Force Spectroscopy
Published in Biophysical journal (08-04-2009)“…Bacterial biofilms are the most prevalent mode of bacterial growth in nature. Adhesive and viscoelastic properties of bacteria play important roles at…”
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Cloning of two gene clusters involved in the catabolism of 2,4-dinitrophenol by Paraburkholderia sp. strain KU-46 and characterization of the initial DnpAB enzymes and a two-component monooxygenases DnpC1C2
Published in Journal of bioscience and bioengineering (01-09-2023)“…Little is currently known about the metabolism of the industrial pollutant 2,4-dinitrophenol (DNP), particularly among gram-negative bacteria. In this study,…”
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Crystal Structures of Cyclohexanone Monooxygenase Reveal Complex Domain Movements and a Sliding Cofactor
Published in Journal of the American Chemical Society (01-07-2009)“…Cyclohexanone monooxygenase (CHMO) is a flavoprotein that carries out the archetypical Baeyer−Villiger oxidation of a variety of cyclic ketones into lactones…”
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Thermostable feruloyl esterase for the bioproduction of ferulic acid from triticale bran
Published in Applied microbiology and biotechnology (01-06-2010)“…A putative α/β hydrolase fold-encoding gene (locus tag TTE1809) from the genome of Thermoanaerobacter tengcongensis was cloned and expressed in Escherichia…”
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Bevacizumab as a steroid‐sparing agent during immunotherapy for melanoma brain metastases: A case series
Published in Health science reports (01-03-2019)“…Background Brain metastases are common in advanced melanoma and often necessitate corticosteroids such as dexamethasone to control symptoms and reduce…”
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High-resolution MRI demonstrates that more than 90% of small intracranial melanoma metastases develop in close relationship to the leptomeninges
Published in Neuro-oncology (Charlottesville, Va.) (05-03-2020)“…Abstract Background Despite classic teaching that intracranial metastases typically arise at the gray–white matter junction, small intracranial melanoma…”
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