Search Results - "Lau, Hudson H. S"

Stereoselectivity of Activation of 7,12-Dimethylbenz[a]anthracene 3,4-Dihydrodiol to the anti-Diol Epoxide Metabolite in a Human Mammary Carcinoma MCF-7 Cell-Mediated V79 Cell Mutation Assay by Lau, Hudson H. S, Coffing, Stephanie L, Lee, Hongmee, Harvey, Ronald G, Baird, William M

“…7,12-Dimethylbenz[a]anthracene (DMBA), one of the most carcinogenic polycyclic aromatic hydrocarbons in rodent bioassays, is metabolically activated in many…”
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Base sequence selectivity in the binding of 7(R),8(S)-dihydroxy-9(S),10(R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene to oligodeoxyribonucleotide duplexes by Schwartz, Jason J, Lau, Hudson H. S, Baird, William M

“…The effect of nucleotide sequence on the binding of 7(R),8(S)-dihydroxy-9(S),10(R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene [(+)-anti-BPDE] to the exocyclic…”
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The potent carcinogen dibenzo[a,l]pyrene is metabolically activated to fjord-region 11,12-diol 13,14-epoxides in human mammary carcinoma MCF-7 cell cultures by RALSTON, S. L, LAU, H. H. S, SEIDEL, A, LUCH, A, PLATT, K. L, BAIRD, W. M

“…Dibenzo[a,l]pyrene (DB[a,l]P), an environmental hydrocarbon and very potent carcinogen in rodent bioassays, could be activated to DNA-binding intermediates in…”
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