Search Results - "Lau, George K."

Serum hepatitis B surface antigen and hepatitis B e antigen titers: Disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers by Thompson, Alexander J.V., Nguyen, Tin, Iser, David, Ayres, Anna, Jackson, Kathy, Littlejohn, Margaret, Slavin, John, Bowden, Scott, Gane, Edward J., Abbott, William, Lau, George K.K., Lewin, Sharon R., Visvanathan, Kumar, Desmond, Paul V., Locarnini, Stephen A.

“…Although threshold levels for hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) titers have recently been proposed to guide therapy for…”
Get full text

Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update by Liaw, Yun-Fan, Leung, Nancy, Kao, Jia-Horng, Piratvisuth, Teerha, Gane, Edward, Han, Kwang-Hyub, Guan, Richard, Lau, George K. K., Locarnini, Stephen

“…Large amounts of new data on the natural history and treatment of chronic hepatitis B virus (HBV) infection have become available since 2005. These include…”
Get full text

Non-alcoholic fatty liver disease in the Asia-Pacific region: Definitions and overview of proposed guidelines by Chitturi, Shivakumar, Farrell, Geoffrey C, Hashimoto, Etsuko, Saibara, Toshiji, Lau, George KK, Sollano, José D

“…Non‐alcoholic fatty liver disease (NAFLD) is the most common liver disorder in Western industrialized countries, affecting 20–40% of the general population…”
Get full text

Silver nanoparticles inhibit hepatitis B virus replication by LEI LU, SUN, Raymond Wai-Yin, RONG CHEN, HUI, Chee-Kin, HO, Chi-Ming, LUK, John M, LAU, George K. K, CHE, Chi-Ming

“…Silver nanoparticles have been shown to exhibit promising cytoprotective activities towards HIV-infected T-cells; however, the effects of these nanoparticles…”
Get full text

Hepatitis B e Antigen Seroconversion: A Critical Event in Chronic Hepatitis B Virus Infection by Liaw, Yun-Fan, Lau, George K. K, Kao, Jia-Horng, Gane, Edward

“…Background Replication of hepatitis B virus (HBV) is the primary driver of disease progression and clinical outcomes in patients with chronic hepatitis B…”
Get full text

APASL consensus statements and recommendation on treatment of hepatitis C by Omata, Masao, Kanda, Tatsuo, Wei, Lai, Yu, Ming-Lung, Chuang, Wang-Long, Ibrahim, Alaaeldin, Lesmana, Cosmas Rinaldi Adithya, Sollano, Jose, Kumar, Manoj, Jindal, Ankur, Sharma, Barjesh Chander, Hamid, Saeed S., Dokmeci, A. Kadir, Mamun-Al-Mahtab, McCaughan, Geofferey W., Wasim, Jafri, Crawford, Darrell H. G., Kao, Jia-Horng, Yokosuka, Osamu, Lau, George K. K., Sarin, Shiv Kumar

“…The Asian-Pacific Association for the Study of the Liver (APASL) convened an international working party on the “APASL consensus statements and recommendation…”
Get full text

Drug-Induced Acute-on-Chronic Liver Failure in Asian Patients by Devarbhavi, Harshad, Choudhury, Ashok Kumar, Sharma, Manoj Kumar, Maiwall, Rakhi, Al Mahtab, Mamun, Rahman, Salimur, Chawla, Yogesh K, Dhiman, Radha K, Duseja, Ajay, Taneja, Sunil, Ning, Qin, Jia, Ji Dong, Duan, Zhongping, Yu, Chen, Eapen, Chundamannil E, Goel, Ashish, Tan, Soek Siam, Hamid, Saeed Sadiq, Butt, Amna Subhan, Jafri, Wasim, Kim, Dong Joon, Hu, Jinhua, Sood, Ajit, Midha, Vandana, Shukla, Akash, Ghazinian, Hasmik, Sahu, Manoj Kumar, Treeprasertsuk, Sombat, Lee, Guan Huei, Lim, Seng Gee, Lesmana, L A, Lesmana, Cosmas Rinaldi, Shah, Samir, Kalal, Chetan, Abbas, Zaigham, Sollano, Jose D, Prasad, V G Mohan, Payawal, Diana Alacantra, Dokmeci, A Kadir, Rao, P Nagaraja, Shrestha, Ananta, Lau, George K, Yuen, Man Fung, Saraswat, Vivek A, Shiha, Gamal, Yokosuka, Osamu, Kedarisetty, Chandan Kumar, Jain, Priyanka, Bhatia, Puja, Sarin, Shiv K

“…Acute insults from viruses, infections, or alcohol are established causes of decompensation leading to acute-on-chronic liver failure (ACLF). Information…”
Get full text

HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa‐2a for HBeAg‐positive chronic hepatitis B by Fried, Michael W., Piratvisuth, Teerha, Lau, George K. K., Marcellin, Patrick, Chow, Wan‐Cheng, Cooksley, Graham, Luo, Kang‐Xian, Paik, Seung Woon, Liaw, Yun‐Fan, Button, Peter, Popescu, Matei

“…The aims of this study were to evaluate the usefulness of quantitative hepatitis B e antigen (HBeAg) values for predicting HBeAg seroconversion in patients…”
Get full text

Human umbilical cord mesenchymal stem cells improve liver function and ascites in decompensated liver cirrhosis patients by Zhang, Zheng, Lin, Hu, Shi, Ming, Xu, Ruonan, Fu, Junliang, Lv, Jiyun, Chen, Liming, Lv, Sa, Li, Yuanyuan, Yu, Shuangjie, Geng, Hua, Jin, Lei, Lau, George K K, Wang, Fu-Sheng

“…Decompensated liver cirrhosis (LC), a life‐threatening complication of chronic liver disease, is one of the major indications for liver transplantation…”
Get full text

APASL consensus statements and recommendations for hepatitis C prevention, epidemiology, and laboratory testing by Omata, Masao, Kanda, Tatsuo, Wei, Lai, Yu, Ming-Lung, Chuang, Wang-Long, Ibrahim, Alaaeldin, Lesmana, Cosmas Rinaldi Adithya, Sollano, Jose, Kumar, Manoj, Jindal, Ankur, Sharma, Barjesh Chander, Hamid, Saeed S., Dokmeci, A. Kadir, Al-Mahtab, Mamun, McCaughan, Geofferey W., Wasim, Jafri, Crawford, Darrell H. G., Kao, Jia-Horng, Yokosuka, Osamu, Lau, George K. K., Sarin, Shiv Kumar

“…The Asian Pacific Association for the Study of the Liver (APASL) convened an international working party on “APASL consensus statements and recommendations for…”
Get full text

Therapeutic vaccination of chronic hepatitis B patients with virus suppression by antiviral therapy: A randomized, controlled study of co-administration of HBsAg/AS02 candidate vaccine and lamivudine by Vandepapelière, Pierre, Lau, George K.K, Leroux-Roels, Geert, Horsmans, Yves, Gane, Edward, Tawandee, Tawesak, Merican, Mohd Ismail bin, Win, Khin Maung, Trepo, Christian, Cooksley, Graham, Wettendorff, Martine, Ferrari, Carlo

“…Abstract Induction of curative immune responses by therapeutic vaccination in chronic viral infections such as chronic hepatitis B (CHB) is expected to be…”
Get full text

Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL) by Sarin, Shiv Kumar, Kumar, Ashish, Almeida, John A., Chawla, Yogesh Kumar, Fan, Sheung Tat, Garg, Hitendra, de Silva, H. Janaka, Hamid, Saeed Sadiq, Jalan, Rajiv, Komolmit, Piyawat, Lau, George K., Liu, Qing, Madan, Kaushal, Mohamed, Rosmawati, Ning, Qin, Rahman, Salimur, Rastogi, Archana, Riordan, Stephen M., Sakhuja, Puja, Samuel, Didier, Shah, Samir, Sharma, Barjesh Chander, Sharma, Praveen, Takikawa, Yasuhiro, Thapa, Babu Ram, Wai, Chun-Tao, Yuen, Man-Fung

“…The Asian Pacific Association for the Study of the Liver (APASL) set up a working party on acute-on-chronic liver failure (ACLF) in 2004, with a mandate to…”
Get full text

Natural history and disease progression in Chinese chronic hepatitis B patients in immune‐tolerant phase by Hui, Chee‐Kin, Leung, Nancy, Yuen, Siu‐Tsan, Zhang, Hai‐Ying, Leung, Kar‐Wai, Lu, Lei, Cheung, Stephen K. F., Wong, Wai‐Man, Lau, George K.

“…In view of the findings that high hepatitis B virus (HBV) deoxyribonucleic acid (DNA) is associated with increased risk of chronic hepatitis B (CHB)–related…”
Get full text

Hepatitis B reactivation after chemotherapy: two decades of clinical research by Lau, George K. K.

“…Hepatitis due to hepatitis B virus reactivation after cytotoxic or immunosuppressive therapy is a serious cause of liver-related morbidity and mortality. With…”
Get full text

Association of Mortalin (HSPA9) with Liver Cancer Metastasis and Prediction for Early Tumor Recurrence by Yi, Xin, Luk, John M., Lee, Nikki P., Peng, Jirun, Leng, Xisheng, Guan, Xin-Yuan, Lau, George K., Beretta, Laura, Fan, Sheung-Tat

“…Hepatocellular carcinoma (HCC) is well known for poor prognosis and short survival because of high recurrence rate even after curative surgery. Today there is…”
Get full text

APASL HCV guidelines of virus-eradicated patients by DAA on how to monitor HCC occurrence and HBV reactivation by Kanda, Tatsuo, Lau, George K. K., Wei, Lai, Moriyama, Mitsuhiko, Yu, Ming-Lung, Chuang, Wang-Long, Ibrahim, Alaaeldin, Lesmana, Cosmas Rinaldi Adithya, Sollano, Jose, Kumar, Manoj, Jindal, Ankur, Sharma, Barjesh Chander, Hamid, Saeed S., Kadir Dokmeci, A., Mamun-Al-Mahtab, McCaughan, Geoffrey W., Wasim, Jafri, Crawford, Darrell H. G., Kao, Jia-Horng, Ooka, Yoshihiko, Yokosuka, Osamu, Sarin, Shiv Kumar, Omata, Masao

“…In the direct-acting antiviral (DAA) era for hepatitis C virus (HCV) infection, sustained virological response (SVR) is very high, but close attention must be…”
Get full text

Guidelines for the assessment and management of non-alcoholic fatty liver disease in the Asia-Pacific region: Executive summary by Farrell, Geoffrey C, Chitturi, Shivakumar, Lau, George KK, Sollano, José D

Get full text

Peginterferon Alfa-2a, Lamivudine, and the Combination for HBeAg-Positive Chronic Hepatitis B by Lau, George K.K, Piratvisuth, Teerha, Luo, Kang Xian, Marcellin, Patrick, Thongsawat, Satawat, Cooksley, Graham, Gane, Edward, Fried, Michael W, Chow, Wan Cheng, Paik, Seung Woon, Chang, Wen Yu, Berg, Thomas, Flisiak, Robert, McCloud, Philip, Pluck, Nigel

“…After 48 weeks of treatment and 24 weeks of follow-up, patients treated with peginterferon either alone or in combination with lamivudine were more likely to…”
Get full text

Peginterferon Alfa-2a Alone, Lamivudine Alone, and the Two in Combination in Patients with HBeAg-Negative Chronic Hepatitis B by Marcellin, Patrick, Lau, George K.K, Bonino, Ferruccio, Farci, Patrizia, Hadziyannis, Stephanos, Jin, Rui, Lu, Zhi-Meng, Piratvisuth, Teerha, Germanidis, Georgios, Yurdaydin, Cihan, Diago, Moises, Gurel, Selim, Lai, Ming-Yang, Button, Peter, Pluck, Nigel

“…Among patients with hepatitis B e antigen (HBeAg)–negative chronic hepatitis B, the rates of suppression of hepatitis B virus DNA to below 20,000 copies per…”
Get full text

Features of hepatitis C virus infection, current therapies and ongoing clinical trials in ten Asian Pacific countries by Omata, Masao, Kanda, Tatsuo, Yokosuka, Osamu, Crawford, Darrell, Al-Mahtab, Mamun, Wei, Lai, Ibrahim, Alaaeldin, Lau, George K. K., Sharma, Barjesh C., Hamid, Saeed S., Chuang, Wan-Long, Dokmeci, A. Kadir

“…Estimated hepatitis C virus (HCV) infection rates in the general populations were 1.3, 0.9, 0.4–1.0, 14.7, 0.1–0.3, 0.9–1.9, 1.0–2.0, 5, 4.4–8.6 and 0.5–1.3 %…”
Get full text