Search Results - "Lau, David H. W."

The peripheral serotonergic pathway: a new target for treating erectile dysfunction? by Lau, David H W, Thompson, Cecil S, Mikhailidis, Dimitri P

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Doxazosin and Serotonin (5-HT) Receptor (1A, 2A, and 4) Antagonists Inhibit 5-HT-Mediated Human Cavernosal Contraction by Lau, David H. W, Thompson, Cecil S, Bellringer, James F, Thomas, Philip J, Mumtaz, Faiz H, Morgan, Robert J, Mikhailidis, Dimitri P

“…Penile erection results from the balance between relaxation and contractile mechanisms of the corpus cavernosum. Only a few studies suggest a role for…”
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Angiotensin II Increases Corpus Cavernosal Contractility and Oxidative Stress in Partial Bladder Outlet Obstructed Rabbits: Relevance to Erectile Dysfunction by Ertemi, Hani, Lau, David H.W., Mikhailidis, Dimitri P., Mumtaz, Faiz H., Thompson, Cecil S.

“…We investigated the effect angiotensin II (Ang II), a corpus cavernosal smooth muscle (CCSM) constrictor peptide, has on tissue taken from rabbits following…”
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Gene therapy and erectile dysfunction: the current status by Lau, David H. W., Kommu, Sashi S., Siddiqui, Emad J., Thompson, Cecil S., Morgan, Robert J., Mikhailidis, Dimitri P., Mumtaz, Faiz H.

“…Current available treatment options for erectile dysfunction (ED) are effective but not without failure and/or side effects. Although the development of…”
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Serotonin induces a biphasic response in rabbit cavernosal smooth muscle: relevance to the erectile process by Lau, David H W, Thompson, Cecil S, Mumtaz, Faiz H, Morgan, Robert J, Mikhailidis, Dimitri P

“…Serotonin (5-hydroxytryptamine; 5-HT) can cause contraction in cavernosal smooth muscle. We further evaluated this effect of 5-HT. Organ bath studies were…”
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Relaxation effects of adrenomedullin in isolated rabbit corpus cavernosum smooth muscle by Lau, David H.W., Kommu, Sash

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The management of phosphodiesterase-5 (PDE5) inhibitor failure by Lau, David H W, Kommu, Sashi, Mumtaz, Faiz H, Morgan, Robert J, Thompson, Cecil S, Mikhailidis, Dimitri P

“…The oral phosphodiesterase type 5 (PDE5) inhibitors have made a valuable contribution to the treatment of erectile dysfunction (ED). PDE5 inhibitors enhance…”
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Re: prostate cancer detection with office based saturation biopsy in a repeat biopsy population by Kommu, Sashi, Lau, David H W, Kommu, Kiran, Emtage, Jerry B, Persad, Raj

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Increasing prostate biopsy cores based on volume vs the sextant biopsy: a prospective randomized controlled clinical study on cancer detection rates and morbidity by Kommu, Sashi, Lau, David H.W., Hadway, Paul, Patel, Suril, Persad, Raj A., Watkin, Nick A.

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In vivo and in vitro response of corpus cavernosum to phosphodiesterase‐5 inhibition in the hypercholesterolaemic rabbit by Lau, David H.W., Thompson, Cecil S., Morgan, Robert J., Mumtaz, Faiz H., Mikhailidis, Dimitri P.

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Pharmacological Properties of Endothelin-1 in the Rabbit Corpus Cavernosum by Mumtaz, Faiz H, Lau, David H W, Siddiqui, Emad J, Thompson, Cecil S, Morgan, Robert J, Mikhailidis, Dimitri P

“…Background: Endothelin (ET-1) may play a role in the regulation of erection but this has not been conclusively demonstrated. Augmented cavernosal smooth muscle…”
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Erectile dysfunction: a need for greater awareness by Lau, David H W, Mumtaz, Faiz H, Thompson, Cecil S, Mikhailidis, Dimitri P

“…Research has led to effective treatment regimes for erectile dysfunction (ED). Convincing evidence links vascular risk factors (hypertension, diabetes…”
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