Search Results - "Lau, Daryl T"

IFITM1 is a tight junction protein that inhibits hepatitis C virus entry by Wilkins, Courtney, Woodward, Jessica, Lau, Daryl T.‐Y., Barnes, Amy, Joyce, Michael, McFarlane, Nicola, McKeating, Jane A., Tyrrell, D. Lorne, Gale, Michael

“…Type 1 interferon (IFN) continues to be the foundation for the current standard of care combination therapy for chronic hepatitis C virus (HCV) infection, yet…”
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A Treatment Algorithm for the Management of Chronic Hepatitis B Virus Infection in the United States: 2015 Update by Martin, Paul, Lau, Daryl T.-Y, Nguyen, Mindie H, Janssen, Harry L.A, Dieterich, Douglas T, Peters, Marion G, Jacobson, Ira M

“…Chronic hepatitis B (CHB) continues to be an important public health problem worldwide, including in the United States. An algorithm for managing CHB was…”
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Hepatitis B virus infection by Yuen, Man-Fung, Chen, Ding-Shinn, Dusheiko, Geoffrey M., Janssen, Harry L. A., Lau, Daryl T. Y., Locarnini, Stephen A., Peters, Marion G., Lai, Ching-Lung

“…Hepatitis B virus (HBV) is a hepatotropic virus that can establish a persistent and chronic infection in humans through immune anergy. Currently, 3.5% of the…”
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A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook by Kramvis, Anna, Chang, Kyong-Mi, Dandri, Maura, Farci, Patrizia, Glebe, Dieter, Hu, Jianming, Janssen, Harry L. A., Lau, Daryl T. Y., Penicaud, Capucine, Pollicino, Teresa, Testoni, Barbara, Van Bömmel, Florian, Andrisani, Ourania, Beumont-Mauviel, Maria, Block, Timothy M., Chan, Henry L. Y., Cloherty, Gavin A., Delaney, William E., Geretti, Anna Maria, Gehring, Adam, Jackson, Kathy, Lenz, Oliver, Maini, Mala K., Miller, Veronica, Protzer, Ulrike, Yang, Jenny C., Yuen, Man-Fung, Zoulim, Fabien, Revill, Peter A.

“…Globally, 296 million people are infected with hepatitis B virus (HBV), and approximately one million people die annually from HBV-related causes, including…”
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Application of the Doylestown algorithm for the early detection of hepatocellular carcinoma by Mehta, Anand S, Lau, Daryl T-Y, Wang, Mengjun, Islam, Aysha, Nasir, Bilal, Javaid, Asad, Poongkunran, Mugilan, Block, Timothy M

“…We previously developed a logistic regression algorithm that uses AFP, age, gender, ALK and ALT levels to improve the detection of hepatocellular carcinoma…”
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Interferon regulatory factor‐3 activation, hepatic interferon‐stimulated gene expression, and immune cell infiltration in hepatitis C virus patients by Lau, Daryl T.‐Y., Fish, Penny Mar, Sinha, Mala, Owen, David M., Lemon, Stanley M., Gale, Michael

“…Interferon regulatory factor‐3 (IRF‐3) activation directs α/β interferon production and interferon‐stimulated gene (ISG) expression, which limits virus…”
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Immune-Escape Mutations Are Prevalent among Patients with a Coexistence of HBsAg and Anti-HBs in a Tertiary Liver Center in the United States by Ali, Mukarram Jamat, Shah, Pir Ahmed, Rehman, Khalil Ur, Kaur, Satinder, Holzmayer, Vera, Cloherty, Gavin A, Kuhns, Mary C, Lau, Daryl T Y

“…The concurrent seropositivity of HBsAg and anti-HBs has been described among patients with chronic hepatitis B (CHB), but its prevalence is variable. HBV…”
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IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease by Negash, Amina A, Ramos, Hilario J, Crochet, Nanette, Lau, Daryl T Y, Doehle, Brian, Papic, Neven, Delker, Don A, Jo, Juandy, Bertoletti, Antonio, Hagedorn, Curt H, Gale, Jr, Michael

“…Chronic hepatitis C virus (HCV) infection is a leading cause of liver disease. Liver inflammation underlies infection-induced fibrosis, cirrhosis and liver…”
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Innate Immune Tolerance and the Role of Kupffer Cells in Differential Responses to Interferon Therapy Among Patients With HCV Genotype 1 Infection by Lau, Daryl T.–Y, Negash, Amina, Chen, Jie, Crochet, Nanette, Sinha, Mala, Zhang, Yuhong, Guedj, Jeremie, Holder, Sharon, Saito, Takeshi, Lemon, Stanley M, Luxon, Bruce A, Perelson, Alan S, Gale, Michael

“…Background & Aims In patients with hepatitis C virus (HCV) infection, interferon alfa (IFN-α) alters expression of IFN-stimulated genes (ISGs), but little is…”
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Comparison of HBV RNA and Hepatitis B Core Related Antigen With Conventional HBV Markers Among Untreated Adults With Chronic Hepatitis B in North America by Ghany, Marc G., King, Wendy C., Lisker‐Melman, Mauricio, Lok, Anna S.F., Terrault, Norah, Janssen, Harry L.A., Khalili, Mandana, Chung, Raymond T., Lee, William M., Lau, Daryl T.Y., Cloherty, Gavin A., Sterling, Richard K.

“…Background and Aims The clinical utility of two biomarkers, hepatitis B virus (HBV) RNA and hepatitis B core‐related antigen (HBcrAg), as compared to…”
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Navigating TREAT-B in resource-limited settings by Kramvis, Anna, Lau, Daryl T Y

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Correction: Application of the Doylestown algorithm for the early detection of hepatocellular carcinoma by Mehta, Anand S, Lau, Daryl T-Y, Wang, Mengjun, Aslam, Aysha, Nasir, Bilal, Javaid, Asad, Poongkunran, Mugilan, Block, Timothy M

“…[This corrects the article DOI: 10.1371/journal.pone.0203149.]…”
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Analysis of ISG expression in chronic hepatitis C identifies viperin as a potential antiviral effector by HELBIG, Karla J, LAU, Daryl T.-Y, SEMENDRIC, Ljiljana, HARLEY, Hugh A. J, BEARD, Michael R

“…Interferon (IFN) alpha inhibits hepatitis C virus (HCV) replication both clinically and in vitro; however, the complete spectrum of interferon-stimulated genes…”
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Recent advances in micro/nanotechnologies for global control of hepatitis B infection by Yildiz, U. Hakan, Inci, Fatih, Wang, ShuQi, Toy, Mehlika, Tekin, H. Cumhur, Javaid, Asad, Lau, Daryl T.-Y., Demirci, Utkan

“…The control of hepatitis B virus (HBV) infection is a challenging task, specifically in developing countries there is limited access to diagnostics and…”
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Hepatic IFN-Induced Protein with Tetratricopeptide Repeats Regulation of HCV Infection by Ishida, Yuji, Kakuni, Masakazu, Bang, Bo-Ram, Sugahara, Go, Lau, Daryl T-Y, Tateno-Mukaidani, Chise, Li, Meng, Gale, Jr, Michael, Saito, Takeshi

“…Interferons (IFNs) suppress viral infection through the induction of >400 interferon-stimulated genes (ISGs). Among ISGs, IFN-induced protein with…”
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Long-Term Therapy of Chronic Hepatitis B With Lamivudine by Lau, Daryl T, Farooq Khokhar, M, Doo, Edward, Ghany, Marc G, Herion, David, Park, Yoon, Kleiner, David E, Schmid, Peter, Condreay, Lynn D, Gauthier, Josée, Kuhns, Mary C, Jake Liang, T, Hoofnagle, Jay H

“…Lamivudine therapy induces improvements in chronic hepatitis B in a high proportion of patients, but prolonged therapy is limited by the development of viral…”
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Low Incidence of Adverse Outcomes in Adults With Chronic Hepatitis B Virus Infection in the Era of Antiviral Therapy by Lok, Anna S., Perrillo, Robert, Lalama, Christina M., Fried, Michael W., Belle, Steven H., Ghany, Marc G., Khalili, Mandana, Fontana, Robert J., Sterling, Richard K., Terrault, Norah, Feld, Jordan J., Di Bisceglie, Adrian M., Lau, Daryl T.Y., Hassan, Mohamed, Janssen, Harry L.A., Chung, Raymond T, Roberts, Lewis R, Lisker‐Melman, Mauricio, Wong, David K, Juan, Joshua, Yim, Colina, Patel, Keyur, Lee, William M, Murakami, Carol S, Do, Son, Han, Steven‐Huy B, Tran, Tram T, Cooper, Stewart L, Tsai, Naoky, Younoszai, Barak, Muir, Andrew, Evon, Donna, Darling, Jama M, Carithers, Robert C, Kowdley, Kris V, Wang, Chia C, Luketic, Velimir A, Jake Liang, T, Hoofnagle, Jay H, Doo, Edward, Chang, Kyong‐Mi, Park, Jang‐June, Wahed, Abdus, King, Wendy C, Kleiner, David

“…Background and Aims Outcomes of persons with chronic hepatitis B virus (HBV) infection in the era of antiviral therapy (AVT) are not well characterized. We…”
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Randomized Trial of Tenofovir With or Without Peginterferon Alfa Followed by Protocolized Treatment Withdrawal in Adults With Chronic Hepatitis B by Terrault, Norah A., Lok, Anna S., Wahed, Abdus S., Ghany, Marc G., Perrillo, Robert P., Fried, Michael W., Wong, David K., Khalili, Mandana, Lau, Daryl T.Y., Sterling, Richard K., Di Bisceglie, Adrian M., Lisker-Melman, Mauricio, Cooper, Stewart L., Chung, Ray T., Patel, Keyur, Roberts, Lewis R., Belle, Steven H., Janssen, Harry L.A.

“…Hepatitis B surface antigen (HBsAg) loss is associated with improved long-term outcomes of patients with chronic hepatitis B but is infrequently achieved with…”
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A framework for management of hepatitis C in prisons by SPAULDING, Anne C, WEINBAUM, Cindy M, LAU, Daryl T.-Y, STERLING, Richard, SEEFF, Leonard B, MARGOLIS, Harold S, HOOFNAGLE, Jay H

“…The prevalence of chronic hepatitis C virus (HCV) infection in prisons ranges from 12% to 31%. There are generally accepted--albeit still evolving--guidelines…”
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Intrahepatic distribution of hepatitis B virus antigens in patients with and without hepatocellular carcinoma by Safaie, Parham, Poongkunran, Mugilan, Kuang, Ping-Ping, Javaid, Asad, Jacobs, Carl, Pohlmann, Rebecca, Nasser, Imad, Lau, Daryl T Y

“…AIM: To study the intrahepatic expression of hepatitis B surface antigen(HBs Ag) and hepatitis B core antigen(HBc Ag) in chronic hepatitis B patients with and…”
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