Search Results - "Lau, Alyssa"
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Balancing up and downregulation of the C. elegans X chromosomes
Published in Current opinion in genetics & development (01-04-2015)“…In Caenorhabditis elegans , males have one X chromosome and hermaphrodites have two. Emerging evidence indicates that the male X is transcriptionally more…”
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Anchoring of Heterochromatin to the Nuclear Lamina Reinforces Dosage Compensation-Mediated Gene Repression
Published in PLoS genetics (30-09-2016)“…Higher order chromosome structure and nuclear architecture can have profound effects on gene regulation. We analyzed how compartmentalizing the genome by…”
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3
Binding-Induced Molecular Amplifier as a Universal Detection Platform for Biomolecules and Biomolecular Interaction
Published in Analytical chemistry (Washington) (17-07-2018)“…Techniques that detect multiple classes of biomolecules and biomolecular interactions from biological or patient samples are highly desirable for applications…”
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4
One-carbon-mediated purine synthesis underlies temozolomide resistance in glioblastoma
Published in Cell death & disease (25-10-2024)“…Glioblastoma accounts for nearly half of all primary malignant brain tumors in adults, and despite an aggressive standard of care, including excisional surgery…”
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5
The C. elegans dosage compensation complex mediates interphase X chromosome compaction
Published in Epigenetics & chromatin (27-10-2014)“…Dosage compensation is a specialized gene regulatory mechanism which equalizes X-linked gene expression between sexes. In Caenorhabditis elegans, dosage…”
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Condensin-mediated chromosome organization and gene regulation
Published in Frontiers in genetics (13-01-2015)“…In many organisms sexual fate is determined by a chromosome-based method which entails a difference in sex chromosome-linked gene dosage. Consequently, a gene…”
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An H4K16 histone acetyltransferase mediates decondensation of the X chromosome in C. elegans males
Published in Epigenetics & chromatin (19-10-2016)“…In , in order to equalize gene expression between the sexes and balance X and autosomal expression, two steps are believed to be required. First, an unknown…”
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Activation of the Ca(2+)-sensing receptor increases renal claudin-14 expression and urinary Ca(2+) excretion
Published in American journal of physiology. Renal physiology (15-03-2013)“…Kidney stones are a prevalent clinical condition imposing a large economic burden on the healthcare system. Hypercalciuria remains the major risk factor for…”
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Ethnocultural influences in how people prefer to obtain and receive health information
Published in Journal of clinical nursing (01-04-2018)“…Aims and objectives To develop an understanding of south Asian and Chinese people's preferences about where to find health information and how best to receive…”
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Abstract PR012: A novel plasma-based epigenomic assay for comprehensive profiling of cancerous and inflammatory disease states
Published in Clinical cancer research (13-11-2024)“…Abstract Background: We developed a method for comprehensive epigenomic profiling from 1 ml of patient (pt) plasma, targeting histone modifications and DNA…”
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Abstract 963: Comprehensive epigenomic profiling from plasma to inform therapy selection: A proof-of-concept study in cancer
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract BACKGROUND: Analysis of genomic alterations in circulating tumor DNA is gaining traction in clinical oncology and can provide insights into tumor…”
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12
Pluripotent cells will not dosage compensate
Published in Worm (Austin, TX) (01-07-2014)“…Dosage compensation is the mechanism that balances gene expression levels between males and females as well as between the X chromosome and autosomes. In…”
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Condensin and Chromatin Mediated X Chromosome Architecture in Caenorhabditis elegans
Published 01-01-2016“…Dosage compensation is an essential gene regulatory mechanism that balances X-linked gene expression and X to autosomal expression in organisms that utilize a…”
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Dissertation -
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Casinos threaten Hong Kong's largest taxpayer; Macao attractions and illegal bookies cause drop in crucial racetrack revenues
Published in International herald tribune (11-11-2005)Get full text
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Can famous mooncakes go green? Food
Published in International herald tribune (15-09-2005)Get full text
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Rallies mark Hong Kong anniversary
Published in International herald tribune (02-07-2005)Get full text
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Hong Kong reverses Falun Gong convictions; Highest court bases judgment on rights, including free speech
Published in International herald tribune (06-05-2005)Get full text
Newspaper Article