Search Results - "Latzer, Joachim"

Conformational Switching upon Phosphorylation:  A Predictive Framework Based on Energy Landscape Principles by Lätzer, Joachim, Shen, Tongye, Wolynes, Peter G.

“…We investigate how post-translational phosphorylation modifies the global conformation of a protein by changing its free energy landscape using two test…”
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Prediction of Native-State Hydrogen Exchange from Perfectly Funneled Energy Landscapes by Craig, Patricio O, Lätzer, Joachim, Weinkam, Patrick, Hoffman, Ryan M. B, Ferreiro, Diego U, Komives, Elizabeth A, Wolynes, Peter G

“…Simulations based on perfectly funneled energy landscapes often capture many of the kinetic features of protein folding. We examined whether simulations based…”
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Consequences of localized frustration for the folding mechanism of the IM7 protein by Sutto, Ludovico, Lätzer, Joachim, Hegler, Joseph A, Ferreiro, Diego U, Wolynes, Peter G

“…In the laboratory, IM7 has been found to have an unusual folding mechanism in which an "on-pathway" intermediate with nonnative interactions is formed. We show…”
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Abstract 1505: From Pandemic to Providence: The Success of the S-STEM Mentored Pathways Program Post-Pandemic by Hofler, Alexandra, Mjahed, Mourad, Latzer, Joachim, Bergdahl, Mikael, Purse, Byron, Alchehayed, Ashley, Eddy, Rebecca, Hecht, David, Komperda, Regis

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Computational Analysis of CHP‐NHE Protein‐Protein Interaction by Bell, Isaac Walter, Latzer, Joachim, Provost, Joseph John

“…Abstract only The Sodium Hydrogen Exchanger (NHE1) is an ATP independent membrane transporter that exchanges an intracellular proton for an extracellular…”
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Restriction versus guidance in protein structure prediction by Hegler, Joseph A, Lätzer, Joachim, Shehu, Amarda, Clementi, Cecilia, Wolynes, Peter G

“…Conformational restriction by fragment assembly and guidance in molecular dynamics are alternate conformational search strategies in protein structure…”
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Frustrational Analysis of Na+/H+ Exchanger 1 (NHE1) and Calcineurin B Homologous Protein 1 & 2 by Silva, Daniela, Latzer, Joachim, Wallert, Mark, Provost, Joseph John

“…Abstract only The sodium hydrogen exchanger isoform 1 (NHE1) is involved in tumor cell proliferation, metastasis, invasion and morbidity in several cancers…”
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Induced Fit, Folding, and Recognition of the NF-κB-Nuclear Localization Signals by IκBα and IκBβ by Lätzer, Joachim, Papoian, Garegin A., Prentiss, Michael C., Komives, Elizabeth A., Wolynes, Peter G.

“…Protein structure prediction codes based on the associative memory Hamiltonian were used to probe the binding modes between the nuclear localization signal…”
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A Comparison of SIKE and WIT 3 Structure and Dynamics by Machek, Megan, Minzer, Ian, Standen, Heather, Kim, Seung‐Hwan, Latzer, Joachim, Bell, Ellis, Bell, Jessica

“…Abstract only Suppressor of IKKe (SIKE)inhibits TBK1 mediated phosphorylation of interferon regulatory factor 3 (IRF3) and misregulation of TBK1 is involved in…”
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Structural Impact of Phosphorylation on the Dynamic Properties of SIKE by Minzer, Ian, Machek, Megan, Standen, Heather, Kim, Seung‐Hwan, Latzer, Joachim, Bell, Ellis, Bell, Jessica

“…Abstract only Suppressor of IKKe (SIKE)inhibits TBK1 mediated phosphorylation of interferon regulatory factor 3 (IRF3) and misregulation of TBK1 is involved in…”
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Simulation studies of the fidelity of biomolecular structure ensemble recreation by Lätzer, Joachim, Eastwood, Michael P, Wolynes, Peter G

“…We examine the ability of Bayesian methods to recreate structural ensembles for partially folded molecules from averaged data. Specifically we test the ability…”
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CUREs in biochemistry—where we are and where we should go by Bell, Jessica K., Eckdahl, Todd T., Hecht, David A., Killion, Patrick J., Latzer, Joachim, Mans, Tamara L., Provost, Joseph J., Rakus, John F., Siebrasse, Erica A., Ellis Bell, J.

“…Integration of research experience into classroom is an important and vital experience for all undergraduates. These course‐based undergraduate research…”
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Computational tools based on energy landscape theory to predict structurally diverse ensembles of transcription factors by Latzer, Joachim

“…The NF-κB/IκB system provides a challenge to the structure-function paradigm since both binding partners are partially disordered in the monomeric form. The…”
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Analysis of Native H/D Exchange Dynamics in EX1/EX2 Conditions using Structure Based Model Simulations by Craig, Patricio O., Hoffman, Ryan M.B., Lätzer, Joachim, Weinkam, Patrick, Komives, Elizabeth A., Wolynes, Peter G.

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Prediction of H Exchange from Perfectly Funneled Structure Based Models by Craig, Patricio O., Lätzer, Joachim, Weinkam, Patrick, Hoffman, Ryan, Komives, Elizabeth, Wolynes, Peter

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Induced fit, folding, and recognition of the NF-kappaB-nuclear localization signals by IkappaBalpha and IkappaBbeta by Lätzer, Joachim, Papoian, Garegin A, Prentiss, Michael C, Komives, Elizabeth A, Wolynes, Peter G

“…Protein structure prediction codes based on the associative memory Hamiltonian were used to probe the binding modes between the nuclear localization signal…”
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