Search Results - "Lattoo, Surrinder"

NADPH-cytochrome P450 reductase: molecular cloning and functional characterization of two paralogs from Withania somnifera (L.) dunal by Rana, Satiander, Lattoo, Surrinder K, Dhar, Niha, Razdan, Sumeer, Bhat, Wajid Waheed, Dhar, Rekha S, Vishwakarma, Ram

“…Withania somnifera (L.) Dunal, a highly reputed medicinal plant, synthesizes a large array of steroidal lactone triterpenoids called withanolides. Although its…”
Get full text

Jasmonate responsive transcription factor WsMYC2 regulates the biosynthesis of triterpenoid withanolides and phytosterol via key pathway genes in Withania somnifera (L.) Dunal by Sharma, Arti, Rather, Gulzar A., Misra, Prashant, Dhar, Manoj K., Lattoo, Surrinder K.

“…Key message Functional characterization of Ws MYC2 via artificial microRNA mediated silencing and transient over-expression displayed significant regulatory…”
Get full text

Molecular and functional characterization of two isoforms of chalcone synthase and their expression analysis in relation to flavonoid constituents in Grewia asiatica L by Wani, Tareq A, Pandith, Shahzad A, Gupta, Ajai P, Chandra, Suresh, Sharma, Namrata, Lattoo, Surrinder K

“…Chalcone synthase constitutes a functionally diverse gene family producing wide range of flavonoids by catalyzing the initial step of the phenylpropanoid…”
Get full text

Gene clustering and co-expression analysis for the identification of putative transcription factors associated with the genes of secondary metabolic pathways in Plantago ovata Forsk. and its wild allies by Gupta, Suruchi, Singh, Ravail, Paul, Prosenjit, Kaul, Sanjana, Lattoo, Surrinder K., Dhar, Manoj K.

“…Genus Plantago of Plantaginaceae family is bestowed with a repertoire of structurally diverse secondary metabolites that have not only been used as…”
Get full text

A Decade of Molecular Understanding of Withanolide Biosynthesis and In vitro Studies in Withania somnifera (L.) Dunal: Prospects and Perspectives for Pathway Engineering by Dhar, Niha, Razdan, Sumeer, Rana, Satiander, Bhat, Wajid W, Vishwakarma, Ram, Lattoo, Surrinder K

“…Withania somnifera, a multipurpose medicinal plant is a rich reservoir of pharmaceutically active triterpenoids that are steroidal lactones known as…”
Get full text

De novo transcriptome analyses reveals putative pathway genes involved in biosynthesis and regulation of camptothecin in Nothapodytes nimmoniana (Graham) Mabb by Rather, Gulzar A., Sharma, Arti, Pandith, Shahzad A., Kaul, Veenu, Nandi, Utpal, Misra, Prashant, Lattoo, Surrinder K.

“…Key message Comprehensive transcriptome analysis of leaf and root tissues of Nothapodytes nimmoniana unravels several putative pathway genes, transcription…”
Get full text

Comprehensive transcriptome analysis provides insights into metabolic and gene regulatory networks in trichomes of Nicotiana tabacum by Nautiyal, Abhishek Kumar, Gani, Umar, Sharma, Priyanka, Kundan, Maridul, Fayaz, Mohd, Lattoo, Surrinder K., Misra, Prashant

“…Key message Comprehensive transcriptome analysis suggested that the primary metabolism is modulated to augment the supply of substrates towards secondary…”
Get full text

Cloning and Functional Characterization of Three Branch Point Oxidosqualene Cyclases from Withania somnifera (L.) Dunal by Dhar, Niha, Rana, Satiander, Razdan, Sumeer, Bhat, Wajid Waheed, Hussain, Aashiq, Dhar, Rekha S., Vaishnavi, Samantha, Hamid, Abid, Vishwakarma, Ram, Lattoo, Surrinder K.

“…Oxidosqualene cyclases (OSCs) positioned at a key metabolic subdividing junction execute indispensable enzymatic cyclization of 2,3-oxidosqualene for varied…”
Get full text

Metabolic and transcriptional analyses in response to potent inhibitors establish MEP pathway as major route for camptothecin biosynthesis in Nothapodytes nimmoniana (Graham) Mabb by Rather, Gulzar A, Sharma, Arti, Jeelani, Syed Mudassir, Misra, Prashant, Kaul, Veenu, Lattoo, Surrinder K

“…Nothapodytes nimmoniana, a plant of pivotal medicinal significance is a source of potent anticancer monoterpene indole alkaloid (MIA) camptothecin (CPT). This…”
Get full text

In-vitro cytotoxicity in relation to chemotypic diversity in diploid and tetraploid populations of Gentiana kurroo Royle by Jeelani, Syed Mudassir, Singh, Jasvinder, Sharma, Arti, Rather, Gulzar A., Ali, Sheikh Abid, Gupta, Ajai Prakash, Singh, Shashank, Lattoo, Surrinder K.

“…Gentiana kurroo is a multipurpose critically endangered medicinal herb prescribed as medicine in Ayurveda in India and exhibits various pharmacological…”
Get full text

Phytochemical evaluation of major bioactive compounds in different cytotypes of five species of Rumex L by Jeelani, Syed Mudassir, Farooq, Umer, Gupta, Ajai Prakash, Lattoo, Surrinder K.

“…[Display omitted] •The identification and quantification of major bioactive compounds in five Rumex species among extant cytotypes has been…”
Get full text

Molecular characterization of UGT94F2 and UGT86C4, two glycosyltransferases from Picrorhiza kurrooa: comparative structural insight and evaluation of substrate recognition by Bhat, Wajid Waheed, Dhar, Niha, Razdan, Sumeer, Rana, Satiander, Mehra, Rukmankesh, Nargotra, Amit, Dhar, Rekha S, Ashraf, Nasheeman, Vishwakarma, Ram, Lattoo, Surrinder K

“…Uridine diphosphate glycosyltransferases (UGTs) are pivotal in the process of glycosylation for decorating natural products with sugars. It is one of the…”
Get full text

Functional Promiscuity of Two Divergent Paralogs of Type III Plant Polyketide Synthases by Pandith, Shahzad A., Dhar, Niha, Rana, Satiander, Bhat, Wajid Waheed, Kushwaha, Manoj, Gupta, Ajai P., Shah, Manzoor A., Vishwakarma, Ram, Lattoo, Surrinder K.

“…Plants effectively defend themselves against biotic and abiotic stresses by synthesizing diverse secondary metabolites, including health-protective flavonoids…”
Get full text

Comparative transcriptome mining for terpenoid biosynthetic pathway genes in wild and cultivated species of Plantago by Gupta, Suruchi, Singh, Ravail, Sharma, Arti, Rather, Gulzar A., Lattoo, Surrinder K., Dhar, Manoj K.

“…Plantagos are important economical and medicinal plants that possess several bioactive secondary metabolites, such as phenolics, iridoids, triterpenes, and…”
Get full text

Secalonic Acid-D Represses HIF1α/VEGF-Mediated Angiogenesis by Regulating the Akt/mTOR/p70S6K Signaling Cascade by Guru, Santosh Kumar, Pathania, Anup Singh, Kumar, Suresh, Ramesh, Deshidi, Kumar, Manjeet, Rana, Satiander, Kumar, Ajay, Malik, Fayaz, Sharma, P R, Chandan, B K, Jaglan, Sundeep, Sharma, J P, Shah, Bhahwal Ali, Tasduq, Sheikh Abdullah, Lattoo, Surrinder K, Faruk, Abdul, Saxena, A K, Vishwakarma, R A, Bhushan, Shashi

“…Tumor angiogenesis is a validated target for therapeutic intervention, but agents that are more disease selective are needed. Here, we report the isolation of…”
Get full text

Phytochemical Diversity in Relation to Cytogenetic Variability in Inula racemosa Hook.f., an Endangered Medicinal Plant of Himalayas by Mudassir Jeelani, Syed, Shahnawaz, Mohd, Prakash Gupta, Ajai, Lattoo, Surrinder K.

“…Inula racemosa, a resourceful critically endangered medicinal herb in the Himalayas is traditionally utilized to cure various human disorders. The species is a…”
Get full text

Characterization and overexpression of sterol Δ22-desaturase, a key enzyme modulates the biosyntheses of stigmasterol and withanolides in Withania somnifera (L.) Dunal by Sharma, Arti, Rana, Satiander, Rather, Gulzar A., Misra, Prashant, Dhar, Manoj K., Lattoo, Surrinder K.

“…•Withanolides represent a dynamic class of metabolites which are derived from diverse scaffolds of phytosterols that are produced in minute…”
Get full text

Rheum australe, an endangered high-value medicinal herb of North Western Himalayas: a review of its botany, ethnomedical uses, phytochemistry and pharmacology by Pandith, Shahzad A., Dar, Riyaz Ahmad, Lattoo, Surrinder K., Shah, Manzoor A., Reshi, Zafar A.

“…Rheum australe (Himalayan Rhubarb) is a multipurpose, endemic and endangered medicinal herb of North Western Himalayas. It finds extensive use as a medicinal…”
Get full text

Identification and bioactive potential of endophytic fungi isolated from selected plants of the Western Himalayas by Qadri, Masroor, Johri, Sarojini, Shah, Bhahwal A, Khajuria, Anamika, Sidiq, Tabasum, Lattoo, Surrinder K, Abdin, Malik Z, Riyaz-Ul-Hassan, Syed

“…This study was conducted to characterize and explore the endophytic fungi of selected plants from the Western Himalayas for their bioactive potential. A total…”
Get full text

Molecular characterization and overexpression analyses of secologanin synthase to understand the regulation of camptothecin biosynthesis in Nothapodytes nimmoniana (Graham.) Mabb by Rather, Gulzar A., Sharma, Arti, Misra, Prashant, Kumar, Amit, Kaul, Veenu, Lattoo, Surrinder K.

“…Camptothecin is a high-value anti-cancerous compound produced in many taxonomically unrelated species. Its biosynthesis involves a complex network of pathways…”
Get full text