Search Results - "Lattmann, Pornthip"

Novel anti-bacterials against MRSA: synthesis of focussed combinatorial libraries of tri-substituted 2(5H)-furanones by Lattmann, Eric, Sattayasai, Nison, Schwalbe, Carl S, Niamsanit, Suwanna, Billington, David C, Lattmann, Pornthip, Langley, Christopher A, Singh, Harjit, Dunn, Simon

“…Mucobromic and mucochloric acid were used as building blocks for the construction of a chemical combinatorial library of 3,4,5-trisubstituted 2(5H)-furanones…”
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Novel, isoform-selective, cholecystokinin A receptor antagonist inhibits colon and pancreatic cancers in preclinical models through novel mechanism of action by PONNUSAMY, SURIYAN, LATTMANN, ERIC, LATTMANN, PORNTHIP, THIYAGARAJAN, THIRUMAGAL, PADINJARETHALAKAL, BALARAM N, NARAYANAN, RAMESH

“…Colon and pancreatic cancers contribute to 90,000 deaths each year in the USA. These cancers lack targeted therapeutics due to heterogeneity of the disease and…”
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Analgesic Effects of 5-Alkyloxy-4-amino-2(5H)-furanones as Cholecystokinin-2 Antagonists by Lattmann, Eric, Sattayasai, Jintana, Schwalbe, Carl H., Boonprakob, Yodchai, Dunn, Simon, Fajana, Feyisayo, Lattmann, Pornthip

“…4‐Amino‐2(5H)‐furanones were synthesized in high yields over two synthetic steps from readily available mucochloric acid. These…”
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Antidepressant/anxiolytic and anti-nociceptive effects of novel 2-substituted 1,4-benzodiazepine-2-ones by Singh, Harjit, Sattayasai, Jintana, Lattmann, Pornthip, Boonprakob, Yodchai, Lattmann, Eric

“…Oxazepam (4a) has been used as overall starting material in the synthesis of novel 2-substituted 1,4-benzodiazepines.By reacting Oxazepam 4a with commercially…”
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Synthesis and evaluation of N-(3-oxo-2,3-dihydro-1 H -pyrazol-4-yl)-1 H -indole-carboxamides as cholecystokinin antagonists by Lattmann, Eric, Singh, Harjit, Lattmann, Pornthip, Boonprakob, Yodchai, Sattayasai, Jintana

“…Abstract The structure-activity relationship optimization of the pyrazoline template 3a resulted in novel…”
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Synthesis and evaluation of N-(3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-1H-indole-carboxamides as cholecystokinin antagonists by Lattmann, Eric, Singh, Harjit, Lattmann, Pornthip, Boonprakob, Yodchai, Sattayasai, Jintana

“…The structure‐activity relationship optimization of the pyrazoline template 3a resulted in novel 3‐oxo‐1,2‐diphenyl‐2,3‐dihydro‐1H‐pyrazol‐4‐yl)‐indole…”
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Synthesis of Substituted 3‐Anilino‐5‐phenyl‐1,3‐dihydro‐ 2 H ‐1,4‐benzodiazepine‐2‐ones and their Evaluation as Cholecystokinin‐Ligands by Offel, Michael, Lattmann, Pornthip, Singh, Harjit, Billington, D. C., Bunprakob, Yodchai, Sattayasai, Jintana, Lattmann, Eric

“…Abstract 3‐Amino‐1,4‐benzodiazepines as well as chemically related diverse amines were prepared from oxazepam and subsequently screened on the cholecystokinin…”
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Synthesis of Substituted 3-Anilino-5-phenyl-1,3-dihydro- 2H-1,4-benzodiazepine-2-ones and their Evaluation as Cholecystokinin-Ligands by Offel, Michael, Lattmann, Pornthip, Singh, Harjit, Billington, D. C., Bunprakob, Yodchai, Sattayasai, Jintana, Lattmann, Eric

“…3‐Amino‐1,4‐benzodiazepines as well as chemically related diverse amines were prepared from oxazepam and subsequently screened on the cholecystokinin receptor…”
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Cholecystokinin antagonists (part 1): Antinociceptive, anxiolytic and antidepressant effects of N-(5-methyl-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazol-4-yl)-N'-phenylureas and carboxamides by Lattmann, E, Sattayasai, J, Boonprakob, Y, Singh, H, Lattmann, P, Dunn, S

“…The SAR optimization of the pyrazoline template resulted in novel 3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazol-4-yl)-indole carboxamides and novel…”
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Anti-depressant and anti-nociceptive effects of 1,4-benzodiazepine-2-ones based cholecystokinin (CCK(2)) antagonists by Lattmann, E, Sattayasai, J, Lattmann, P, Billington, D C, Schwalbe, C H, Boonprakob, J, Airarat, W, Singh, H, Offel, M, Staaf, A

“…Various 1,4-benzodiazepines were synthesized around a Diazepam, Oxazepam and the n-propyl-1,4-benzodiazepine template. SAR studies of CCK(2) binding affinity…”
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In vivo Evaluation of Substituted 3-Amino-1,4-benzodiazepines as Anti-depressant, Anxiolytic and Anti-nociceptive Agents by LATTMANN, Eric, LATTMANN, Pornthip, BOONPRAKOB, Yodchai, AIRARAT, Wanchai, SINGH, Harjit, OFFEL, Michael, SATTAYASAI, Jintana

“…Oxazepam (CAS 604-75-1) 4a served as building block in the synthesis of substituted 3-amino-1,4-benzodiazepines, which were subsequently tested in various CNS…”
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Synthesis and evaluation of N-(5-methyl-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazol-4-yl)-N'-phenylureas as cholecystokinin antagonists by LATTMANN, Eric, SATTAYASAI, Jintana, BOONPRAKOB, Yodchai, LATTMANN, Pornthip, SINGH, Harjit

“…In the search for new cholecystokinin (CCK) ligands, ureidopyrazolines were identified in combinatorial libraries using 168 chemically diverse amines. The…”
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