Search Results - "Latoche, Joseph R."

Phenotype and genetics of progressive sensorineural hearing loss (Snhl1) in the LXS set of recombinant inbred strains of mice by Noben-Trauth, Konrad, Latoche, Joseph R, Neely, Harold R, Bennett, Beth

“…Progressive sensorineural hearing loss is the most common form of acquired hearing impairment in the human population. It is also highly prevalent in inbred…”
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Controlled cortical impact and craniotomy induce strikingly similar profiles of inflammatory gene expression, but with distinct kinetics by Lagraoui, Mouna, Latoche, Joseph R, Cartwright, Natalia G, Sukumar, Gauthaman, Dalgard, Clifton L, Schaefer, Brian C

“…An immediate consequence of traumatic brain injury (TBI) is the induction of an inflammatory response. Mounting data suggest that inflammation is a major…”
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Polygenic inheritance of sensorineural hearing loss ( Snhl2, -3, and -4) and organ of Corti patterning defect in the ALR/LtJ mouse strain by Latoche, Joseph R., Neely, Harold R., Noben-Trauth, Konrad

“…Progressive sensorineural hearing loss in humans is a common and debilitating impairment. Sensorineural deafness in inbred strains of mice is a similarly…”
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High-Frequency Sensorineural Hearing Loss and Its Underlying Genetics (Hfhl1 and Hfhl2) in NIH Swiss Mice by Keller, James M., Neely, Harold R., Latoche, Joseph R., Noben-Trauth, Konrad

“…Studies using inbred strains of mice have been invaluable for identifying alleles that adversely affect hearing. However, the efficacy of those studies is…”
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Salsalate treatment following traumatic brain injury reduces inflammation and promotes a neuroprotective and neurogenic transcriptional response with concomitant functional recovery by Lagraoui, Mouna, Sukumar, Gauthaman, Latoche, Joseph R, Maynard, Sean K, Dalgard, Clifton L, Schaefer, Brian C

“…Highlights • Salsalate inhibits inflammatory gene expression following traumatic brain injury. • Salsalate also induces genes involved with neuroprotection and…”
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Ectopic Mineralization in the Middle Ear and Chronic Otitis Media with Effusion Caused by RPL38 Deficiency in the Tail-short (Ts) Mouse by Noben-Trauth, Konrad, Latoche, Joseph R.

“…Inflammation of the middle ear cavity (otitis media) and the abnormal deposition of bone at the otic capsule are common causes of conductive hearing impairment…”
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T cell receptor signals to NF-κB are transmitted by a cytosolic p62-Bcl10-Malt1-IKK signalosome by Paul, Suman, Traver, Maria K, Kashyap, Anuj K, Washington, Michael A, Latoche, Joseph R, Schaefer, Brian C

“…Antigen-mediated stimulation of the T cell receptor (TCR) triggers activation of nuclear factor κB (NF-κB), a key transcriptional regulator of T cell…”
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Gipc3 mutations associated with audiogenic seizures and sensorineural hearing loss in mouse and human by Noben-Trauth, Konrad, Charizopoulou, Nikoletta, Lelli, Andrea, Schraders, Margit, Ray, Kausik, Hildebrand, Michael S, Ramesh, Arabandi, Srisailapathy, C. R. Srikumari, Oostrik, Jaap, Admiraal, Ronald J. C, Neely, Harold R, Latoche, Joseph R, Smith, Richard J. H, Northup, John K, Kremer, Hannie, Holt, Jeffrey R

“…Sensorineural hearing loss affects the quality of life and communication of millions of people, but the underlying molecular mechanisms remain elusive. Here,…”
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Phenotype and Genetics of Progressive Sensorineural Hearing Loss by Noben-Trauth, Konrad, Latoche, Joseph R, Neely, Harold R, Bennett, Beth

“…Progressive sensorineural hearing loss is the most common form of acquired hearing impairment in the human population. It is also highly prevalent in inbred…”
Get full text