Search Results - "Latoche, Joseph D."

Prevention of breast cancer-induced osteolytic bone resorption by benzyl isothiocyanate by Pore, Subrata K, Hahm, Eun-Ryeong, Latoche, Joseph D, Anderson, Carolyn J, Shuai, Yongli, Singh, Shivendra V

“…A subset of patients on bisphosphonates or anti-RANKL antibody still develop new bone metastasis or experience adverse effects. The present study demonstrates…”
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ImmunoPET imaging of TIGIT in the glioma microenvironment by Vincze, Sarah R., Jaswal, Ambika P., Frederico, Stephen C., Nisnboym, Michal, Li, Bo, Xiong, Zujian, Sever, ReidAnn E., Sneiderman, Chaim T., Rodgers, Mikayla, Day, Kathryn E., Latoche, Joseph D., Foley, Lesley M., Hitchens, T. Kevin, Frederick, Robin, Patel, Ravi B., Hadjipanayis, Costas G., Raphael, Itay, Nedrow, Jessie R., Edwards, W. Barry, Kohanbash, Gary

“…Glioblastoma (GBM) is the most common primary malignant brain tumor. Currently, there are few effective treatment options for GBM beyond surgery and…”
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Dual-labeled anti-GD2 targeted probe for intraoperative molecular imaging of neuroblastoma by Rosenblum, Lauren Taylor, Sever, ReidAnn E, Gilbert, Ryan, Guerrero, David, Vincze, Sarah R, Menendez, Dominic M, Birikorang, Peggy A, Rodgers, Mikayla R, Jaswal, Ambika Parmar, Vanover, Alexander C, Latoche, Joseph D, Cortez, Angel G, Day, Kathryn E, Foley, Lesley M, Sneiderman, Chaim T, Raphael, Itay, Hitchens, T Kevin, Nedrow, Jessie R, Kohanbash, Gary, Edwards, W Barry, Malek, Marcus M

“…Surgical resection is integral for the treatment of neuroblastoma, the most common extracranial solid malignancy in children. Safely locating and resecting…”
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Patients with cystic fibrosis have inducible IL-17+ IL-22+ memory cells in lung draining lymph nodes by Chan, Yvonne R., MD, Chen, Kong, PhD, Duncan, Steven R., MD, Lathrop, Kira L., MAMS, Latoche, Joseph D., BS, Logar, Alison J., BS, Pociask, Derek A., PhD, Wahlberg, Brendon J., MS, Ray, Prabir, PhD, Ray, Anuradha, PhD, Pilewski, Joseph M., MD, Kolls, Jay K., MD

“…Background IL-17 is an important cytokine signature of the TH differentiation pathway TH 17. This T-cell subset is crucial in mediating autoimmune disease or…”
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Novel theranostic agent for PET imaging and targeted radiopharmaceutical therapy of tumour-infiltrating immune cells in glioma by Foster, Alexandra, Nigam, Shubhanchi, Tatum, David S, Raphael, Itay, Xu, Jide, Kumar, Rajeev, Plakseychuk, Elizabeth, Latoche, Joseph D, Vincze, Sarah, Li, Bo, Giri, Rajan, McCarl, Lauren H, Edinger, Robert, Ak, Murat, Peddagangireddy, Vishal, Foley, Lesley M, Hitchens, T Kevin, Colen, Rivka R, Pollack, Ian F, Panigrahy, Ashok, Magda, Darren, Anderson, Carolyn J, Edwards, W Barry, Kohanbash, Gary

“…Malignant gliomas are deadly tumours with few therapeutic options. Although immunotherapy may be a promising therapeutic strategy for treating gliomas, a…”
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Targeted imaging of very late antigen-4 for noninvasive assessment of lung inflammation-fibrosis axis by Zhu, Qin, Barnes, Clayton E., Mannes, Philip Z., Latoche, Joseph D., Day, Kathryn E., Nedrow, Jessie R., Novelli, Enrico M., Anderson, Carolyn J., Tavakoli, Sina

“…Background The lack of noninvasive methods for assessment of dysregulated inflammation as a major driver of fibrosis (i.e., inflammation-fibrosis axis) has…”
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Evaluation of the pharmacokinetics, dosimetry, and therapeutic efficacy for the α-particle-emitting transarterial radioembolization (αTARE) agent [225Ac]Ac-DOTA-TDA-Lipiodol® against hepatic tumors by Josefsson, Anders, Cortez, Angel G., Rajkumar, Harikrishnan, Latoche, Joseph D., Jaswal, Ambika P., Day, Kathryn E., Zarisfi, Mohammadreza, Rigatti, Lora H., Huang, Ziyu, Nedrow, Jessie R.

“…Background The liver is a common site for metastatic disease for a variety of cancers, including colorectal cancer. Both primary and secondary liver tumors are…”
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Retraction: Innate Immune Activation by Inhaled Lipopolysaccharide, Independent of Oxidative Stress, Exacerbates Silica-Induced Pulmonary Fibrosis in Mice by Brass, David M, Spencer, Jennifer C, Li, Zhuowei, Potts-Kant, Erin, Reilly, Sarah M, Dunkel, Mary K, Latoche, Joseph D, Auten, Richard L, Hollingsworth, John W, Fattman, Cheryl L

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Innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice by Brass, David M, Spencer, Jennifer C, Li, Zhuowei, Potts-Kant, Erin, Reilly, Sarah M, Dunkel, Mary K, Latoche, Joseph D, Auten, Richard L, Hollingsworth, John W, Fattman, Cheryl L

“…Acute exacerbations of pulmonary fibrosis are characterized by rapid decrements in lung function. Environmental factors that may contribute to acute…”
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Validation of Ultrasound Super-Resolution Imaging of Vasa Vasorum in Rabbit Atherosclerotic Plaques by Chen, Qiyang, Yu, Jaesok, Lukashova, Lyudmila, Latoche, Joseph D., Zhu, Jianhui, Lavery, Linda, Verdelis, Konstantinos, Anderson, Carolyn J., Kim, Kang

“…Acute coronary syndromes and strokes are mainly caused by atherosclerotic plaque (AP) rupture. Abnormal increase of vasa vasorum (VV) is reported as a key…”
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Molecular imaging of chemokine-like receptor 1 (CMKLR1) in experimental acute lung injury by Mannes, Philip Z, Barnes, Clayton E, Biermann, Jana, Latoche, Joseph D, Day, Kathryn E, Zhu, Qin, Tabary, Mohammadreza, Xiong, Zeyu, Nedrow, Jessie R, Izar, Benjamin, Anderson, Carolyn J, Villanueva, Flordeliza S, Lee, Janet S, Tavakoli, Sina

“…The lack of techniques for noninvasive imaging of inflammation has challenged precision medicine management of acute respiratory distress syndrome (ARDS)…”
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Molecular Imaging of Very Late Antigen-4 in Acute Lung Injury by Haddad, Joseph, Latoche, Joseph D, Nigam, Shubhanchi, Bellavia, Michael C, Day, Kathryn E, Zhu, Qin, Edwards, W Barry, Anderson, Carolyn J, Tavakoli, Sina

“…Inflammation plays a central role in the pathogenesis of acute lung injury (ALI) during both the acute pneumonitis stage and progression into the chronic…”
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Modular Smart Molecules for PSMA-Targeted Chemotherapy by Olatunji, Feyisola P, Pun, Michael, Herman, Jacob W, Romero, Oscar, Maniatopoulos, Mitchell, Latoche, Joseph D, Parise, Robert A, Guo, Jianxia, Beumer, Jan H, Anderson, Carolyn J, Berkman, Clifford E

“…New targeted chemotherapeutics are urgently needed to minimize off-target toxicity and reduce the high-mortality rate associated with metastatic prostate…”
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Secreted Phosphoprotein 1 and Sex-Specific Differences in Silica-Induced Pulmonary Fibrosis in Mice by Latoche, Joseph D, Ufelle, Alexander Chukwuma, Fazzi, Fabrizio, Ganguly, Koustav, Leikauf, George D, Fattman, Cheryl L

“…Fibrotic lung diseases occur predominantly in males, and reports describe better survival in affected females. Male mice are more sensitive to silica-induced…”
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2-deoxy-2-[18F]fluoro-D-glucose Positron Emission Tomography to Monitor Lung Inflammation and Therapeutic Response to Dexamethasone in a Murine Model of Acute Lung Injury by Mannes, Philip Z., Barnes, Clayton E., Latoche, Joseph D., Day, Kathryn E., Nedrow, Jessie R., Lee, Janet S., Tavakoli, Sina

“…Purpose To image inflammation and monitor therapeutic response to anti-inflammatory intervention using 2-deoxy-2-[ 18 F]fluoro-D-glucose ([ 18 F]FDG) positron…”
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Dietary intake and glutamine-serine metabolism control pathologic vascular stiffness by Rachedi, Nesrine S, Tang, Ying, Tai, Yi-Yin, Zhao, Jingsi, Chauvet, Caroline, Grynblat, Julien, Akoumia, Kouamé Kan Firmin, Estephan, Leonard, Torrino, Stéphanie, Sbai, Chaima, Ait-Mouffok, Amel, Latoche, Joseph D, Al Aaraj, Yassmin, Brau, Frederic, Abélanet, Sophie, Clavel, Stephan, Zhang, Yingze, Guillermier, Christelle, Kumar, Naveen V G, Tavakoli, Sina, Mercier, Olaf, Risbano, Michael G, Yao, Zhong-Ke, Yang, Guangli, Ouerfelli, Ouathek, Lewis, Jason S, Montani, David, Humbert, Marc, Steinhauser, Matthew L, Anderson, Carolyn J, Oldham, William M, Perros, Frédéric, Bertero, Thomas, Chan, Stephen Y

“…Perivascular collagen deposition by activated fibroblasts promotes vascular stiffening and drives cardiovascular diseases such as pulmonary hypertension (PH)…”
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Patients with cystic fibrosis have inducible IL-17IL-22 memory cells in lung draining lymph nodes by Chan, Yvonne R, Chen, Kong, Duncan, Steven R, Lathrop, Kira L, Latoche, Joseph D, Logar, Alison J, Pociask, Derek A, Wahlberg, Brendon J, Ray, Prabir, Ray, Anuradha, Pilewski, Joseph M, Kolls, Jay K

“…Background IL-17 is an important cytokine signature of the TH differentiation pathway TH17. This T-cell subset is crucial in mediating autoimmune disease or…”
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Preclinical Dosimetry, Imaging, and Targeted Radionuclide Therapy Studies of Lu-177-Labeled Albumin-Binding, PSMA-Targeted CTT1403 by Ling, Xiaoxi, Latoche, Joseph D., Choy, Cindy J., Kurland, Brenda F., Laymon, Charles M., Wu, Yijen, Salamacha, Nathan, Shen, Ding, Geruntho, Jonathan J., Rigatti, Lora H., Windish, Hillarie P., Langton-Webster, Beatrice, Berkman, Clifford E., Anderson, Carolyn J.

“…Purpose Prostate-specific membrane antigen (PSMA) continues to be the hallmark biomarker for prostate cancer as it is expressed on nearly all prostatic tumors…”
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A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer-Induced Osteolytic Bone Resorption by Pore, Subrata K, Hahm, Eun-Ryeong, Kim, Su-Hyeong, Singh, Krishna B, Nyiranshuti, Lea, Latoche, Joseph D, Anderson, Carolyn J, Adamik, Juraj, Galson, Deborah L, Weiss, Kurt R, Watters, Rebecca J, Lee, Boeun, Kumta, Prashant N, Singh, Shivendra V

“…Bone is the most preferred site for colonization of metastatic breast cancer cells for each subtype of the disease. The standard of therapeutic care for breast…”
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PET Imaging of VLA-4 in a New BRAFV600E Mouse Model of Melanoma by Bellavia, Michael C., Nyiranshuti, Lea, Latoche, Joseph D., Ho, Khanh-Van, Fecek, Ronald J., Taylor, Jennifer L., Day, Kathryn E., Nigam, Shubhanchi, Pun, Michael, Gallazzi, Fabio, Edinger, Robert S., Storkus, Walter J., Patel, Ravi B., Anderson, Carolyn J.

“…Purpose Despite unprecedented responses to immune checkpoint inhibitors and targeted therapy in melanoma, a major subset of patients progresses and have few…”
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