Search Results - "Latiri, Mehdi"

From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia by Saez-Ayala, Magali, Hoffer, Laurent, Abel, Sébastien, Ben Yaala, Khaoula, Sicard, Benoit, Andrieu, Guillaume P., Latiri, Mehdi, Davison, Emma K., Ciufolini, Marco A., Brémond, Paul, Rebuffet, Etienne, Roche, Philippe, Derviaux, Carine, Voisset, Edwige, Montersino, Camille, Castellano, Remy, Collette, Yves, Asnafi, Vahid, Betzi, Stéphane, Dubreuil, Patrice, Combes, Sébastien, Morelli, Xavier

“…Cancer cells utilize the main de novo pathway and the alternative salvage pathway for deoxyribonucleotide biosynthesis to achieve adequate nucleotide pools…”
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Harnessing the MYB-dependent TAL1 5'super-enhancer for targeted therapy in T-ALL by Smith, Charlotte, Touzart, Aurore, Simonin, Mathieu, Tran-Quang, Christine, Hypolite, Guillaume, Latiri, Mehdi, Andrieu, Guillaume P, Balducci, Estelle, Dourthe, Marie-Émilie, Goyal, Ashish, Huguet, Françoise, Petit, Arnaud, Ifrah, Norbert, Baruchel, André, Dombret, Hervé, Macintyre, Elizabeth, Plass, Christoph, Ghysdael, Jacques, Boissel, Nicolas, Asnafi, Vahid

“…The acquisition of genetic abnormalities engendering oncogene dysregulation underpins cancer development. Certain proto-oncogenes possess several dysregulation…”
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Low level CpG island promoter methylation predicts a poor outcome in adult T-cell acute lymphoblastic leukemia by Touzart, Aurore, Boissel, Nicolas, Belhocine, Mohamed, Smith, Charlotte, Graux, Carlos, Latiri, Mehdi, Lhermitte, Ludovic, Mathieu, Eve-Lyne, Huguet, Françoise, Lamant, Laurence, Ferrier, Pierre, Ifrah, Norbert, Macintyre, Elizabeth, Dombret, Hervé, Asnafi, Vahid, Spicuglia, Salvatore

“…Cancer cells undergo massive alterations in their DNA methylation patterns which result in aberrant gene expression and malignant phenotypes. Abnormal DNA…”
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P321: TNF‐MEDIATED CELL DEATH: AN ACTIONABLE TARGET FOR IMMUNOTHERAPY IN T‐CELL ACUTE LYMPHOBLASTIC LEUKEMIA by Dourthe, Marie‐Emilie, Lengline, Etienne, Charbonnier, Guillaume, Latiri, Mehdi, Saji, Chaimae, Cieslak, Agata, Simonin, Mathieu, Ifrah, Norbert, Dombret, Hervé, Hermine, Olivier, Boissel, Nicolas, Baruchel, André, Ghysdael, Jacques, Macintyre, Elizabeth, Tran‐Quang, Christine, Andrieu, Guillaume, Asnafi, Vahid

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P1166: BRIGATINIB IN PATIENTS WITH ALK‐POSITIVE ANAPLASTIC LARGE CELL LYMPHOMA WHO HAVE FAILED BRENTUXIMAB VEDOTIN by Veleanu, Layla, Tesson, Bruno, Lamant, Laurence, Marçais, Ambroise, Bruneau, Julie, Kaltenbach, Sophie, Brouzes, Chantal, Degoutte, Charlotte, Moraly, Josquin, Villarese, Patrick, Lhermitte, Ludovic, Latiri, Mehdi, Hure, Gregoire, Chauchet, Adrien, Delette, Caroline, Grosleron, Sylvie, Toussaint, Elise, Cabrera, Quentin, Brice, Pauline, Gros, Francois‐Xavier, Clavert, Aline, Oberic, Lucie, Legoff, Marielle, Cereja, Sophie, Meggetto, Fabienne, Macintyre, Elizabeth, Asnafi, Vahid, Sibon, David

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Clinical and biological features of PTPN2-deleted adult and pediatric T-cell acute lymphoblastic leukemia by Alcantara, Marion, Simonin, Mathieu, Lhermitte, Ludovic, Touzart, Aurore, Dourthe, Marie Emilie, Latiri, Mehdi, Grardel, Nathalie, Cayuela, Jean Michel, Chalandon, Yves, Graux, Carlos, Dombret, Hervé, Ifrah, Norbert, Petit, Arnaud, Macintyre, Elizabeth, Baruchel, André, Boissel, Nicolas, Asnafi, Vahid

“…Protein tyrosine phosphatase nonreceptor type 2 (PTPN2) is a phosphatase known to be a tumor suppressor gene in T-cell acute lymphoblastic leukemia (T-ALL)…”
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Roles for the CX3CL1/CX3CR1 and CCL2/CCR2 Chemokine Systems in Hypoxic Pulmonary Hypertension by Amsellem, Valérie, Abid, Shariq, Poupel, Lucie, Parpaleix, Aurélien, Rodero, Mathieu, Gary-Bobo, Guillaume, Latiri, Mehdi, Dubois-Rande, Jean-Luc, Lipskaia, Larissa, Combadiere, Christophe, Adnot, Serge

“…Monocytes/macrophages are major effectors of lung inflammation associated with various forms of pulmonary hypertension (PH). Interactions between the CCL2/CCR2…”
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DNA methylation as a new tool for the differential diagnosis between T‐LBL and lymphocyte‐rich thymoma by Latiri, Mehdi, Belhocine, Mohamed, Smith, Charlotte, Garnier, Nathalie, Balducci, Estelle, Pinton, Antoine, Andrieu, Guillaume P, Bruneau, Julie, Spicuglia, Salvatore, Jamain, Stéphane, Latapie, Violaine, Montpreville, Vincent Thomas, Chalabreysse, Lara, Marx, Alexander, Girard, Nicolas, Besse, Benjamin, Plass, Christoph, Gibault, Laure, Badoual, Cécile, Macintyre, Elizabeth, Asnafi, Vahid, Molina, Thierry Jo, Touzart, Aurore

“…T‐lymphoblastic lymphoma (T‐LBL) and thymoma are two rare primary tumors of the thymus deriving either from T‐cell precursors or from thymic epithelial cells,…”
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Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup by Touzart, Aurore, Mayakonda, Anand, Smith, Charlotte, Hey, Joschka, Toth, Reka, Cieslak, Agata, Andrieu, Guillaume P, Tran Quang, Christine, Latiri, Mehdi, Ghysdael, Jacques, Spicuglia, Salvatore, Dombret, Hervé, Ifrah, Norbert, Macintyre, Elizabeth, Lutsik, Pavlo, Boissel, Nicolas, Plass, Christoph, Asnafi, Vahid

“…Adult "T cell" acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy that is associated with poor outcomes, requiring additional…”
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Epigenetic Silencing Affects l-Asparaginase Sensitivity and Predicts Outcome in T-ALL by Touzart, Aurore, Lengliné, Etienne, Latiri, Mehdi, Belhocine, Mohamed, Smith, Charlotte, Thomas, Xavier, Spicuglia, Salvatore, Puthier, Denis, Pflumio, Françoise, Leguay, Thibaut, Graux, Carlos, Chalandon, Yves, Huguet, Françoise, Leprêtre, Stéphane, Ifrah, Norbert, Dombret, Hervé, Macintyre, Elizabeth, Hunault, Mathilde, Boissel, Nicolas, Asnafi, Vahid

“…Biological explanation for discrepancies in patient-related response to chemotherapy depending on the underlying oncogenic events is a promising research area…”
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Middle age exacerbates acute respiratory distress syndrome in a double hit murine model by Voiriot, Guillaume, Contou, Damien, Tran Van Nhieu, Jeanne, Amsellem, Valerie, Marcos, Elisabeth, Latiri, Mehdi, Adnot, Serge, Maitre, Bernard, Mekontso Dessap, Armand

“…In a recent systematic review, aging has been identified as the only factor independently associated with mortality during human acute respiratory distress…”
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ATP citrate lyase is an essential player in the metabolic rewiring induced by PTEN loss during T-ALL development by Andrieu, Guillaume P., Hypolite, Guillaume, Latiri, Mehdi, Balducci, Estelle, Costa, Caroline, Verhoeyen, Els, Courgeon, Marianne, Allatif, Omran, Nemazanyy, Ivan, Panasyuk, Ganna, Wellen, Kathryn E, Herranz, Daniel, Genestier, Laurent, Macintyre, Elizabeth A., Asnafi, Vahid, Tesio, Melania

“…Alterations inactivating the tumor suppressor gene PTEN drive the development of solid and hematological cancers, such as T-cell acute lymphoblastic leukemia…”
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Adenylate kinase 2 expression and addiction in T-ALL by Maslah, Nabih, Latiri, Mehdi, Asnafi, Vahid, Féroul, Mélanie, Bedjaoui, Nawel, Steimlé, Thomas, Six, Emmanuelle, Verhoyen, Els, Macintyre, Elizabeth, Lagresle-Peyrou, Chantal, Lhermitte, Ludovic, Andrieu, Guillaume P.

“…T-cell acute lymphoblastic leukemia (T-ALL) represents the malignant expansion of immature T cells blocked in their differentiation. T-ALL is still associated…”
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Targeting IRAK1 in T-cell acute lymphoblastic leukemia by Dussiau, Charles, Trinquand, Amélie, Lhermitte, Ludovic, Latiri, Mehdi, Simonin, Mathieu, Cieslak, Agata, Bedjaoui, Nawel, Villarèse, Patrick, Verhoeyen, Els, Dombret, Hervé, Ifrah, Norbert, Macintyre, Elizabeth, Asnafi, Vahid

“…T-cell acute lymphoblastic leukemia (T-ALL) represents expansion of cells arrested at specific stages of thymic development with the underlying genetic…”
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