Search Results - "Lath, Darren L."

ARQ-197, a small-molecule inhibitor of c-Met, reduces tumour burden and prevents myeloma-induced bone disease in vivo by Lath, Darren L, Buckle, Clive H, Evans, Holly R, Fisher, Matthew, Down, Jenny M, Lawson, Michelle A, Chantry, Andrew D

“…The receptor tyrosine kinase c-Met, its ligand HGF, and components of the downstream signalling pathway, have all been implicated in the pathogenesis of…”
Get full text

The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties by Tattersall, Luke, Shah, Karan M., Lath, Darren L., Singh, Archana, Down, Jennifer M., De Marchi, Elena, Williamson, Alex, Di Virgilio, Francesco, Heymann, Dominique, Adinolfi, Elena, Fraser, William D., Green, Darrell, Lawson, Michelle A., Gartland, Alison

“…•P2RX7B expression confers a survival advantage in TE85+P2RX7B and MNNG-HOS+P2RX7B OS cell lines.•P2RX7B expression reduced cell adhesion and activation…”
Get full text

JZL184, A Monoacylglycerol Lipase Inhibitor, Induces Bone Loss in a Multiple Myeloma Model of Immunocompetent Mice by Marino, Silvia, Carrasco, Giovana, Li, Boya, Shah, Karan M., Lath, Darren L., Sophocleous, Antonia, Lawson, Michelle A., Idris, Aymen I.

“…Multiple myeloma (MM) patients develop osteolysis characterised by excessive osteoclastic bone destruction and lack of osteoblast bone formation…”
Get full text

The in vitro and in vivo validation of a mobile non-contact camera-based digital imaging system for tooth colour measurement by Smith, Richard N, Collins, Luisa Z, Naeeni, Mojgan, Joiner, Andrew, Philpotts, Carole J, Hopkinson, Ian, Jones, Clare, Lath, Darren L, Coxon, Thomas, Hibbard, James, Brook, Alan H

“…Abstract Objective To assess the reproducibility of a mobile non-contact camera-based digital imaging system (DIS) for measuring tooth colour under in vitro…”
Get full text