Search Results - "Latasa, Maria U"

Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice by Uriarte, Iker, Fernandez-Barrena, Maite G, Monte, Maria J, Latasa, Maria U, Chang, Haisul C Y, Carotti, Simone, Vespasiani-Gentilucci, Umberto, Morini, Sergio, Vicente, Eva, Concepcion, Axel R, Medina, Juan F, Marin, José Juan G, Berasain, Carmen, Prieto, Jesus, Avila, Matías A

“…Cholestasis is associated with increased liver injury and morbidity after partial hepatectomy (PH), yet bile acids (BAs) are emerging as important mediators of…”
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Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage by González-Recio, Irene, Simón, Jorge, Goikoetxea-Usandizaga, Naroa, Serrano-Maciá, Marina, Mercado-Gómez, Maria, Rodríguez-Agudo, Rubén, Lachiondo-Ortega, Sofía, Gil-Pitarch, Clàudia, Fernández-Rodríguez, Carmen, Castellana, Donatello, Latasa, Maria U., Abecia, Leticia, Anguita, Juan, Delgado, Teresa C., Iruzubieta, Paula, Crespo, Javier, Hardy, Serge, Petrov, Petar D., Jover, Ramiro, Avila, Matías A., Martín, César, Schaeper, Ute, Tremblay, Michel L., Dear, James W., Masson, Steven, McCain, Misti Vanette, Reeves, Helen L., Andrade, Raul J., Lucena, M. Isabel, Buccella, Daniela, Martínez-Cruz, Luis Alfonso, Martínez-Chantar, Maria L

“…Acetaminophen overdose is one of the leading causes of acute liver failure and liver transplantation in the Western world. Magnesium is essential in several…”
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Connective tissue growth factor autocriny in human hepatocellular carcinoma: Oncogenic role and regulation by epidermal growth factor receptor/yes‐associated protein–mediated activation by Urtasun, Raquel, Latasa, Maria U., Demartis, Maria I., Balzani, Stella, Goñi, Saioa, Garcia‐Irigoyen, Oihane, Elizalde, Maria, Azcona, Maria, Pascale, Rosa M., Feo, Francesco, Bioulac‐Sage, Paulette, Balabaud, Charles, Muntané, Jordi, Prieto, Jesus, Berasain, Carmen, Avila, Matias A.

“…The identification of molecular mechanisms involved in the maintenance of the transformed phenotype of hepatocellular carcinoma (HCC) cells is essential for…”
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Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis by Argemi, Josepmaria, Latasa, Maria U., Atkinson, Stephen R., Blokhin, Ilya O., Massey, Veronica, Gue, Joel P., Cabezas, Joaquin, Lozano, Juan J., Van Booven, Derek, Bell, Aaron, Cao, Sheng, Vernetti, Lawrence A., Arab, Juan P., Ventura-Cots, Meritxell, Edmunds, Lia R., Fondevila, Constantino, Stärkel, Peter, Dubuquoy, Laurent, Louvet, Alexandre, Odena, Gemma, Gomez, Juan L., Aragon, Tomas, Altamirano, Jose, Caballeria, Juan, Jurczak, Michael J., Taylor, D. Lansing, Berasain, Carmen, Wahlestedt, Claes, Monga, Satdarshan P., Morgan, Marsha Y., Sancho-Bru, Pau, Mathurin, Philippe, Furuya, Shinji, Lackner, Carolin, Rusyn, Ivan, Shah, Vijay H., Thursz, Mark R., Mann, Jelena, Avila, Matias A., Bataller, Ramon

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Regulation of amphiregulin gene expression by β-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR system by Latasa, Maria U, Salis, Fabiana, Urtasun, Raquel, Garcia-Irigoyen, Oihane, Elizalde, Maria, Uriarte, Iker, Santamaria, Monica, Feo, Francesco, Pascale, Rosa M, Prieto, Jesús, Berasain, Carmen, Avila, Matías A

“…Hepatocellular carcinoma (HCC) is the most prevalent liver tumor and a deadly disease with limited therapeutic options. Dysregulation of cell signaling…”
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Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair by Garcia-Irigoyen, Oihane, Carotti, Simone, Latasa, Maria U., Uriarte, Iker, Fernández-Barrena, Maite G., Elizalde, Maria, Urtasun, Raquel, Vespasiani-Gentilucci, Umberto, Morini, Sergio, Banales, Jesús M., Parks, William C., Rodriguez, Jose A., Orbe, Josune, Prieto, Jesús, Páramo, Jose A., Berasain, Carmen, Ávila, Matías A.

“…Background & Aims Upon tissue injury, the liver mounts a potent reparative and regenerative response. A role for proteases, including serine and matrix…”
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Toll-like receptor-4 expression by hepatic progenitor cells and biliary epithelial cells in HCV-related chronic liver disease by Vespasiani-Gentilucci, Umberto, Carotti, Simone, Onetti-Muda, Andrea, Perrone, Giuseppe, Ginanni-Corradini, Stefano, Latasa, Maria U, Avila, Matias A, Carpino, Guido, Picardi, Antonio, Morini, Sergio

“…Notwithstanding numerous evidences implicating toll-like receptor-4 (TLR4) in the pathogenesis of chronic hepatitis C virus (HCV) infection, the localization…”
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Lack of Abcc3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice by Fernández-Barrena, Maite G, Monte, Maria J, Latasa, Maria U, Uriarte, Iker, Vicente, Eva, Chang, Haisul C.Y, Rodriguez-Ortigosa, Carlos M, Elferink, Ronald Oude, Berasain, Carmen, Marin, Jose J.G, Prieto, Jesus, Ávila, Matias A

“…Background & Aims Bile acids (BA) are increasingly recognized as important modulators of liver regeneration. Increased enterohepatic BA flux has been proposed…”
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Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis by Argemi, Josepmaria, Latasa, Maria U., Atkinson, Stephen R., Blokhin, Ilya O., Massey, Veronica, Gue, Joel P., Cabezas, Joaquin, Lozano, Juan J., Van Booven, Derek, Bell, Aaron, Cao, Sheng, Vernetti, Lawrence A., Arab, Juan P., Ventura-Cots, Meritxell, Edmunds, Lia R., Fondevila, Constantino, Stärkel, Peter, Dubuquoy, Laurent, Louvet, Alexandre, Odena, Gemma, Gomez, Juan L., Aragon, Tomas, Altamirano, Jose, Caballeria, Juan, Jurczak, Michael J., Taylor, D. Lansing, Berasain, Carmen, Wahlestedt, Claes, Monga, Satdarshan P., Morgan, Marsha Y., Sancho-Bru, Pau, Mathurin, Philippe, Furuya, Shinji, Lackner, Carolin, Rusyn, Ivan, Shah, Vijay H., Thursz, Mark R., Mann, Jelena, Avila, Matias A., Bataller, Ramon

“…Alcoholic hepatitis (AH) is a life-threatening condition characterized by profound hepatocellular dysfunction for which targeted treatments are urgently…”
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Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications by Alvarez-Sola, Gloria, Uriarte, Iker, Latasa, Maria U., Jimenez, Maddalen, Barcena-Varela, Marina, Santamaría, Eva, Urtasun, Raquel, Rodriguez-Ortigosa, Carlos, Prieto, Jesús, Berraondo, Pedro, Fernandez-Barrena, Maite G., Berasain, Carmen, Avila, Matías A.

“…The liver has an extraordinary regenerative capacity rapidly triggered upon injury or resection. This response is intrinsically adjusted in its initiation and…”
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The Epidermal Growth Factor Receptor Ligand Amphiregulin Protects From Cholestatic Liver Injury and Regulates Bile Acids Synthesis by Santamaría, Eva, Rodríguez‐Ortigosa, Carlos M., Uriarte, Iker, Latasa, Maria U., Urtasun, Raquel, Alvarez‐Sola, Gloria, Bárcena‐Varela, Marina, Colyn, Leticia, Arcelus, Sara, Jiménez, Maddalen, Deutschmann, Kathleen, Peleteiro‐Vigil, Ana, Gómez‐Cambronero, Julian, Milkiewicz, Malgorzata, Milkiewicz, Piotr, Sangro, Bruno, Keitel, Verena, Monte, Maria J., Marin, Jose J.G., Fernández‐Barrena, Maite G., Ávila, Matias A., Berasain, Carmen

“…Intrahepatic accumulation of bile acids (BAs) causes hepatocellular injury. Upon liver damage, a potent protective response is mounted to restore the organ’s…”
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Redox regulation of methylthioadenosine phosphorylase in liver cells: molecular mechanism and functional implications by Fernández-Irigoyen, Joaquín, Santamaría, Mónica, Sánchez-Quiles, Virginia, Latasa, Maria U, Santamaría, Enrique, Muñoz, Javier, Sánchez Del Pino, Manuel M, Valero, María L, Prieto, Jesús, Avila, Matías A, Corrales, Fernando J

“…MTAP (5'-methylthioadenosine phosphorylase) catalyses the reversible phosphorolytic cleavage of methylthioadenosine leading to the production of…”
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Splicing regulator SLU7 is essential for maintaining liver homeostasis by Elizalde, María, Urtasun, Raquel, Azkona, María, Latasa, María U, Goñi, Saioa, García-Irigoyen, Oihane, Uriarte, Iker, Segura, Victor, Collantes, María, Di Scala, Mariana, Lujambio, Amaia, Prieto, Jesús, Ávila, Matías A, Berasain, Carmen

“…A precise equilibrium between cellular differentiation and proliferation is fundamental for tissue homeostasis. Maintaining this balance is particularly…”
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Matrix metalloproteinase 10 contributes to hepatocarcinogenesis in a novel crosstalk with the stromal derived factor 1/C‐X‐C chemokine receptor 4 axis by García‐Irigoyen, Oihane, Latasa, Maria U., Carotti, Simone, Uriarte, Iker, Elizalde, Maria, Urtasun, Raquel, Vespasiani‐Gentilucci, Umberto, Morini, Sergio, Benito, Patricia, Ladero, Jose M., Rodriguez, Jose A., Prieto, Jesus, Orbe, Josune, Páramo, Jose A., Fernández‐Barrena, Maite G., Berasain, Carmen, Avila, Matias A.

“…Matrix metalloproteinases (MMPs) participate in tissue repair after acute injury, but also participate in cancer by promoting a protumorigenic…”
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Hepatocyte dedifferentiation profiling in alcohol-related liver disease identifies CXCR4 as a driver of cell reprogramming by Aguilar-Bravo, Beatriz, Ariño, Silvia, Blaya, Delia, Pose, Elisa, Martinez García de la Torre, Raquel A., Latasa, María U., Martínez-Sánchez, Celia, Zanatto, Laura, Sererols-Viñas, Laura, Cantallops-Vilà, Paula, Affo, Silvia, Coll, Mar, Thillen, Xavier, Dubuquoy, Laurent, Avila, Matías A., Argemi, Josepmaria, Paz, Arantza Lamas, Nevzorova, Yulia A., Cubero, Francisco Javier, Bataller, Ramon, Lozano, Juan José, Ginès, Pere, Mathurin, Philippe, Sancho-Bru, Pau

“…Loss of hepatocyte identity is associated with impaired liver function in alcohol-related hepatitis (AH). In this context, hepatocyte dedifferentiation gives…”
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Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice by Alvarez-Sola, Gloria, Uriarte, Iker, Latasa, Maria U, Jimenez, Maddalen, Barcena-Varela, Marina, Santamaría, Eva, Urtasun, Raquel, Rodriguez-Ortigosa, Carlos, Prieto, Jesús, Corrales, Fernando J, Baulies, Anna, García-Ruiz, Carmen, Fernandez-Checa, Jose C, Berraondo, Pedro, Fernandez-Barrena, Maite G, Berasain, Carmen, Avila, Matías A

“…The liver displays a remarkable regenerative capacity triggered upon tissue injury or resection. However, liver regeneration can be overwhelmed by excessive…”
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Alterations in the expression and activity of pre-mRNA splicing factors in hepatocarcinogenesis by Berasain, Carmen, Elizalde, María, Urtasun, Raquel, Castillo, Josefa, García-Irigoyen, Oihane, Uriarte, Iker, Latasa, Maria U, Prieto, Jesús, Avila, Matías A

“…Hepatocellular carcinoma (HCC) is a molecularly complex tumor that is resistant to standard and targeted therapies, and thus a deadly disease. In this context,…”
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FRI-464 Caspases compromise SLU7 and UPF1 stability and nonsensemediated RNA decay activity during hepatocarcinogenesis by Rojo, Carla, Gárate-Rascón, María, Recalde, Miriam, Álava, Ane, Elizalde, María, Azkona, Maria, Guruceaga, Elisabet, Lopez-Pascual, Amaya, Latasa, Maria U., Sangro, Bruno, Fernandez-Barrena, Maite G., Avila, Matías A., Arechederra, Maria, Berasain, Carmen

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FRI-538 Novel regulatory mechanisms of the transforming growth factor β signaling pathway by the histone Methyltransferase G9a by Castello, Borja, Lopez-Pascual, Amaya, Herranz, Jose Maria, Elurbide-Tardio, Jasmin, Adan-Villaescusa, Elena, Irigaray-Miramon, Ainara, Latasa, Maria U., Uriarte, Iker, Arechederra, Maria, Fabregat, Isabel, Sangro, Bruno, Berasain, Carmen, Fernandez-Barrena, Maite G., Avila, Matías A.

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FRI-555 New insights into the regulation of bile acids synthesis during the early stages of liver regeneration: a human and experimental study by Uriarte, Iker, Santamaria, Eva, Lopez-Pascual, Amaya, Argemi, Josep Maria, Latasa, Maria U., Adan-Villaescusa, Elena, Irigaray-Miramon, Ainara, Herranz, Jose Maria, Arechederra, Maria, Basualdo, Jorge, Lucena, Felipe, Corrales, Fernando J., Rotellar, Fernando, Pardo, Fernando, Merlen, Grégory, Sangro, Bruno, Tordjmann, Thierry, Berasain, Carmen, Monte, Maria J., Marin, Jose J.G., Fernandez-Barrena, Maite G., Herrero, Jose Ignacio, Avila, Matías A.

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