Search Results - "Lassoued, Wiem"

Enhanced neoepitope-specific immunity following neoadjuvant PD-L1 and TGF-β blockade in HPV-unrelated head and neck cancer by Redman, Jason M, Friedman, Jay, Robbins, Yvette, Sievers, Cem, Yang, Xinping, Lassoued, Wiem, Sinkoe, Andrew, Papanicolau-Sengos, Antonios, Lee, Chyi-Chia, Marte, Jennifer L, Turkbey, Evrim, Mydlarz, Wojtek, Joshi, Arjun, London, Jr, Nyall R, Pierce, Matthew, Taylor, Rodney, Hong, Steven, Nguyen, Andy, Soon-Shiong, Patrick, Schlom, Jeffrey, Gulley, James L, Allen, Clint T

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Correction to: Augmentation of tumor expression of HLADR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses by Larkin, Riley M, Lopez, Diana C, Robbins, Yvette L, Lassoued, Wiem, Canubas, Kenneth, Warner, Andrew, Karim, Baktiar, Vulikh, Ksenia, Hodge, James W, Floudas, Charalampos S, Gulley, James L, Gallia, Gary L, Allen, Clint T, London, Jr, Nyall R

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Augmentation of tumor expression of HLA-DR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses by Larkin, Riley M, Lopez, Diana C, Robbins, Yvette L, Lassoued, Wiem, Canubas, Kenneth, Warner, Andrew, Karim, Baktiar, Vulikh, Ksenia, Hodge, James W, Floudas, Charalampos S, Gulley, James L, Gallia, Gary L, Allen, Clint T, London, Jr, Nyall R

“…Olfactory neuroblastoma is a rare malignancy of the anterior skull base typically treated with surgery and adjuvant radiation. Although outcomes are fair for…”
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Alum-anchored IL-12 combined with cytotoxic chemotherapy and immune checkpoint blockade enhanced antitumor immune responses in head and neck cancer models by Fabian, Kellsye P, Santiago-Sanchez, Ginette, Padget, Michelle R, Lassoued, Wiem, Allen, Clint Tanner, Battula, Sailaja, Kaufman, Howard, Hodge, James W

“…First-line treatment with pembrolizumab plus chemotherapy in recurrent and metastatic head and neck squamous cell carcinomas (HNSCC) has improved survival…”
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Multi-spectral immunofluorescence evaluation of the myeloid, T cell, and natural killer cell tumor immune microenvironment in chordoma may guide immunotherapeutic strategies by Lopez, Diana C., Robbins, Yvette L., Kowalczyk, Joshua T., Lassoued, Wiem, Gulley, James L., Miettinen, Markku M., Gallia, Gary L., Allen, Clint T., Hodge, James W., London, Nyall R.

“…Background Chordoma is a rare, invasive, and devastating bone malignancy of residual notochord tissue that arises at the skull base, sacrum, or spine. In order…”
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Chordoma cancer stem cell subpopulation characterization may guide targeted immunotherapy approaches to reduce disease recurrence by Lopez, Diana C, Fabian, Kellsye P, Padget, Michelle R, Robbins, Yvette L, Kowalczyk, Joshua T, Lassoued, Wiem, Pastor, Danielle M, Allen, Clint T, Gallia, Gary L, Gulley, James L, Hodge, James W, London, Jr, Nyall R

“…Cancer stem cells (CSCs), a group of tumor-initiating and tumor-maintaining cells, may be major players in the treatment resistance and recurrence distinctive…”
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913 Tumor immune micro-environment (TIME) Atlas for prostate cancer bone metastasis by Canubas, Kenneth, Xu, Michael, Kelly, William, Marte, Jennifer, Sater, Houssein Abdul, Gulley, James L, Lassoued, Wiem

“…BackgroundProstate cancer (PC) is the leading cause of cancer incidence among men in the US.1 For patients living with advanced PC, bone metastasis (mets) is a…”
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Inhibition of Tumor Endothelial ERK Activation, Angiogenesis, and Tumor Growth by Sorafenib (BAY43-9006) by Murphy, Danielle A., Makonnen, Sosina, Lassoued, Wiem, Feldman, Michael D., Carter, Christopher, Lee, William M.F.

“…Activation of the Raf-MEK-ERK signal transduction pathway in endothelial cells is required for angiogenesis. Raf is the kinase most efficiently inhibited by…”
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Activated STAT3 is a mediator and biomarker of VEGF endothelial activation by Chen, Shao-Hua, Murphy, Danielle, Lassoued, Wiem, Thurston, Gavin, Feldman, Michael D., Lee, William M.F.

“…STAT3 plays important roles in cell proliferation and survival signaling and is often constitutively activated in transformed cells. In this study, we examined…”
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Efficacy, safety, and biomarker analyses of bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with advanced non-small cell lung cancer by Rajan, Arun, Abdul Sater, Houssein, Rahma, Osama, Agajanian, Richy, Lassoued, Wiem, Marté, Jennifer L, Tsai, Yo-Ting, Donahue, Renee N, Lamping, Elizabeth, Bailey, Shania, Weisman, Andrew, Walter-Rodriguez, Beatriz, Ito, Rena, Vugmeyster, Yulia, Sato, Masashi, Machl, Andreas, Schlom, Jeffrey, Gulley, James L

“…BackgroundBintrafusp alfa, a first-in-class bifunctional fusion protein targeting transforming growth factor-β (TGF-β) and programmed cell death ligand 1, has…”
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587 Nivolumab increased vaccine induced T-cell infiltration in Prostate cancer by Lassoued, Wiem, Burnett, Daniel, Canubas, Kenneth, Bailey, Shania, Marte, Jennifer, William, Nikki, Hankin, Amy, Manukyan, Manuk, Manu, Michell, Dahut, William, Pinto, Peter, Karzai, Fatima, Madan, Ravi, Sater, Houssein Abdul, Gulley, James L

“…BackgroundProstate cancer is the most diagnosed cancer in men worldwide, making up 21% of all cancer cases.1 Although this disease is slow growing, 370,000 men…”
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Effect of VEGF and VEGF Trap on vascular endothelial cell signaling in tumors by Lassoued, Wiem, Murphy, Danielle, Tsai, Jeff, Oueslati, Ridha, Thurston, Gavin, Lee, William M.F.

“…Vascular endothelial growth factor (VEGF) A is a major promoter of tumor angiogenesis and a prime target of antiangiogenic cancer therapy. To examine whether…”
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420 PROSTVAC in combination with nivolumab enhanced immune cell infiltration in prostate cancer by Bailey, Shania, Lassoued, Wiem, Papanicolau-Sengos, Antonios, Marte, Jennifer, Williams, Nikki, Hankin, Amy, Manu, Michell, Dahut, William, Pinto, Peter, Karzai, Fatima, Madan, Ravi, Sater, Houssein Abdul, Gulley, James

“…BackgroundProstate cancer (PC) is the most common non-cutaneous diagnosed cancer among men in USA.1 Although clinical outcomes are favorable for patients with…”
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Improved Automatic Detection and Segmentation of Cell Nuclei in Histopathology Images by Al-Kofahi, Yousef, Lassoued, Wiem, Lee, William, Roysam, Badrinath

“…Automatic segmentation of cell nuclei is an essential step in image cytometry and histometry. Despite substantial progress, there is a need to improve…”
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Enhanced neoepitope-specific immunity following neoadjuvant PD-L1 and TGF-β blockade in HPV-unrelated head and neck cancer by Redman, Jason M, Friedman, Jay, Robbins, Yvette, Sievers, Cem, Yang, Xinping, Lassoued, Wiem, Sinkoe, Andrew, Papanicolau-Sengos, Antonios, Lee, Chyi-Chia, Marte, Jennifer L, Turkbey, Evrim, Mydlarz, Wojtek, Joshi, Arjun, London, Jr, Nyall R, Pierce, Matthew, Taylor, Rodney, Hong, Steven, Nguyen, Andy, Soon-Shiong, Patrick, Schlom, Jeffrey, Gulley, James L, Allen, Clint T

“…BACKGROUNDHead and neck squamous cell carcinoma not associated with HPV (HPV-unrelated HNSCC) is associated with a high rate of recurrence and poor…”
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Tumor cell HLA class I expression and pathologic response following neoadjuvant immunotherapy for newly diagnosed head and neck cancer by Robbins, Yvette, Friedman, Jay, Redman, Jason, Sievers, Cem, Lassoued, Wiem, Gulley, James L., Allen, Clint T.

“…•Tumor cell HLA class I expression is not associated with tumor cell PD-L1 expression.•Tumor cell HLA class I expression after treatment associates with…”
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Prediction of cancer treatment response from histopathology images through imputed transcriptomics by Hoang, Danh-Tai, Dinstag, Gal, Hermida, Leandro C., Ben-Zvi, Doreen, Stossel, Chani, Patil, Tejas, Sammut, Stephen-John, Lassoued, Wiem, Allen, Clint, Beker, Tuvik, Jiang, Peng, Golan, Talia, Sowalsky, Adam G., Pine, Sharon R, Caldas, Carlos, Gulley, James L., Aldape, Kenneth D., Aharonov, Ranit, Stone, Eric, Ruppin, Eytan

“…1551 Background: In recent years, the use of tumour molecular profiling within the clinic has allowed for more accurate cancer diagnostics, as well as the…”
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Enhanced neoepitope-specific immunity following neoadjuvant PD-L1 and TGF-[beta] blockade in HPV-unrelated head and neck cancer by Redman, Jason M, Friedman, Jay, Robbins, Yvette, Sievers, Cem, Yang, Xinping, Lassoued, Wiem, Sinkoe, Andrew, Papanicolau-Sengos, Antonios, Lee, Chyi-Chia, Marte, Jennifer L, Turkbey, Evrim, Mydlarz, Wojtek, Joshi, Arjun, London, Nyall R., Jr, Pierce, Matthew, Taylor, Rodney, Hong, Steven, Nguyen, Andy, Soon-Shiong, Patrick, Schlom, Jeffrey, Gulley, James L, Allen, Clint T

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GNRH2 Polymorphism in Men With Prostate Cancer Treated With Androgen Deprivation Therapy by Sissung, Tristan M, Lochrin, Sarah, Liu, Tyler, Schmidt, Keith, Strope, Jonathan, Risdon, Emily, Choo-Wosoba, Hyoyoung, Venzon, David J, Lassoued, Wiem, Sater, Houssein A, Walter-Rodriguez, Beatriz, Price, Douglas K, Figg, William D

“…Gonadotropin-releasing hormone 2 (GNRH2) is a poorly-studied peptide hormone that is widely distributed in the central nervous system and expressed in…”
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Enhanced neoepitope-specific immunity following neoadjuvant PD-L1 and TGF-[beta] blockade in HPV-unrelated head and neck cancer by Redman, Jason M, Friedman, Jay, Robbins, Yvette, Sievers, Cem, Yang, Xinping, Lassoued, Wiem, Sinkoe, Andrew, Papanicolau-Sengos, Antonios, Lee, Chyi-Chia, Marte, Jennifer L, Turkbey, Evrim, Mydlarz, Wojtek, Joshi, Arjun, London Jr., Nyall R, Pierce, Matthew, Taylor, Rodney, Hong, Steven, Nguyen, Andy, Soon-Shiong, Patrick, Schlom, Jeffrey, Gulley, James L, Allen, Clint T

“…BACKGROUND. Head and neck squamous cell carcinoma not associated with HPV (HPV-unrelated HNSCC) is associated with a high rate of recurrence and poor survival…”
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