Search Results - "Lassaletta, Antonio D"

Engineering a highly elastic human protein-based sealant for surgical applications by Annabi, Nasim, Zhang, Yi-Nan, Assmann, Alexander, Sani, Ehsan Shirzaei, Cheng, George, Lassaletta, Antonio D, Vegh, Andrea, Dehghani, Bijan, Ruiz-Esparza, Guillermo U, Wang, Xichi, Gangadharan, Sidhu, Weiss, Anthony S, Khademhosseini, Ali

“…Surgical sealants have been used for sealing or reconnecting ruptured tissues but often have low adhesion, inappropriate mechanical strength, cytotoxicity…”
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Effects of Alcohol on Postoperative Adhesion Formation in Ischemic Myocardium and Pericardium by Elmadhun, Nassrene Y., MD, Sabe, Ashraf A., MD, Lassaletta, Antonio D., MD, Dalal, Rahul S., MD, Sellke, Frank W., MD

“…Background Postoperative formation of adhesions increases risk of complications during cardiac reoperations. We previously demonstrated that swine supplemented…”
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Therapeutic neovascularization for coronary disease: current state and future prospects by Lassaletta, Antonio D., Chu, Louis M., Sellke, Frank W.

“…Despite advances in surgical and percutaneous revascularization techniques, nearly one-third of patients with ischemic coronary artery disease are not…”
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Hysteresis Drives Cell-Cycle Transitions in Xenopus laevis Egg Extracts by Sha, Wei, Moore, Jonathan, Chen, Katherine, Lassaletta, Antonio D., Yi, Chung-Seon, Tyson, John J., Sible, Jill C.

“…Cells progressing through the cell cycle must commit irreversibly to mitosis without slipping back to interphase before properly segregating their chromosomes…”
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Metabolic syndrome impairs notch signaling and promotes apoptosis in chronically ischemic myocardium by Elmadhun, Nassrene Y., MD, Sabe, Ashraf A., MD, Lassaletta, Antonio D., MD, Chu, Louis M., MD, Kondra, Katelyn, BS, Sturek, Michael, PhD, Sellke, Frank W., MD

“…Objective Impaired angiogenesis is a known consequence of metabolic syndrome (MetS); however, the mechanism is not fully understood. Recent studies have shown…”
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The pig as a valuable model for testing the effect of resveratrol to prevent cardiovascular disease by Elmadhun, Nassrene Y., Sabe, Ashraf A., Robich, Michael P., Chu, Louis M., Lassaletta, Antonio D., Sellke, Frank W.

“…Resveratrol is a naturally occurring polyphenol found in the skin of red grapes, peanuts, and red wine that has been shown to modify many cardiovascular risk…”
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Metformin mitigates apoptosis in ischemic myocardium by Elmadhun, Nassrene Y., MD, Sabe, Ashraf A., MD, Lassaletta, Antonio D., MD, Chu, Louis M., MD, Sellke, Frank W., MD

“…Abstract Background Epidemiologic data has shown that metformin confers a survival advantage in patients with cardiovascular disease. Although the underlying…”
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Atorvastatin increases oxidative stress and modulates angiogenesis in Ossabaw swine with the metabolic syndrome by Elmadhun, Nassrene Y., MD, Lassaletta, Antonio D., MD, Chu, Louis M., MD, Liu, Yuhong, MD, Feng, Jun, MD, Sellke, Frank W., MD

“…Objective The purpose of the present study was to evaluate the effect of atorvastatin on oxidative stress and angiogenesis in ischemic myocardium in a…”
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Alcohol and the Heart: A Proteomics Analysis of Pericardium and Myocardium in a Swine Model of Myocardial Ischemia by Elmadhun, Nassrene Y., MD, Sadek, Ahmed A., BS, Sabe, Ashraf A., MD, Lassaletta, Antonio D., MD, Sellke, Frank W., MD

“…Background Previous studies have demonstrated that moderate alcohol consumption is cardioprotective and reduces postoperative pericardial adhesions; however,…”
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Early Cellular Changes in the Ascending Aorta and Myocardium in a Swine Model of Metabolic Syndrome by Saraf, Rabya, Huang, Thomas, Mahmood, Feroze, Owais, Khurram, Bardia, Amit, Khabbaz, Kamal R, Liu, David, Senthilnathan, Venkatachalam, Lassaletta, Antonio D, Sellke, Frank, Matyal, Robina

“…Metabolic syndrome is associated with pathological remodeling of the heart and adjacent vessels. The early biochemical and cellular changes underlying the…”
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Microvascular Notch Signaling Is Upregulated in Response to Vascular Endothelial Growth Factor and Chronic Myocardial Ischemia by Lassaletta, Antonio D., Elmadhun, Nassrene Y., Burgess, Thomas A., Bianchi, Cesario, Sabe, Ashraf A., Robich, Michael P., Chu, Louis M., Sellke, Frank W.

“…Background: Notch signaling is a highly conserved pathway that promotes vascular and myocardial growth. The hypothesis that exogenous vascular endothelial…”
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Metformin alters the insulin signaling pathway in ischemic cardiac tissue in a swine model of metabolic syndrome by Elmadhun, Nassrene Y., MD, Lassaletta, Antonio D., MD, Chu, Louis M., MD, Sellke, Frank W., MD

“…Objective The purpose of this study is to evaluate the effect of metformin on insulin signaling in ischemic cardiac tissue in a swine model of metabolic…”
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Effects of alcohol on pericardial adhesion formation in hypercholesterolemic swine by Lassaletta, Antonio D., MD, Chu, Louis M., MD, Sellke, Frank W., MD

“…Objective Reoperative cardiac surgery is complicated in part because of extensive adhesions encountered during the second operation. The purpose of this study…”
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Alcohol Consumption Mitigates Apoptosis and Mammalian Target of Rapamycin Signaling in Myocardium by Elmadhun, Nassrene Y., MD, Sabe, Ashraf A., MD, Lassaletta, Antonio D., MD, Sellke, Frank W., MD, FACS

“…Background Epidemiologic studies have shown that individuals who consume low to moderate alcohol have a lower risk of cardiovascular disease developing…”
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Rapamycin Treatment of Healthy Pigs Subjected to Acute Myocardial Ischemia-Reperfusion Injury Attenuates Cardiac Functions and Increases Myocardial Necrosis by Lassaletta, Antonio D., MD, Elmadhun, Nassrene Y., MD, Zanetti, Arthus V.D, Feng, Jun, MD, PhD, Anduaga, Javier, BS, Gohh, Reginald Y., MD, Sellke, Frank W., MD, Bianchi, Cesario, MD, PhD

“…Background The mammalian target of rapamycin (mTOR) pathway is a major regulator of cell immunity and metabolism. mTOR is a well-known suppressor of tissue…”
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A highly adhesive and naturally derived sealant by Assmann, Alexander, Vegh, Andrea, Ghasemi-Rad, Mohammad, Bagherifard, Sara, Cheng, George, Sani, Ehsan Shirzaei, Ruiz-Esparza, Guillermo U, Noshadi, Iman, Lassaletta, Antonio, Gangadharan, Sidhu, Tamayol, Ali, Khademhosseini, Ali, Annabi, Nasim

“…Abstract Conventional surgical techniques to seal and repair defects in highly stressed elastic tissues are insufficient. Therefore, this study aimed to…”
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Ethanol promotes new vessel growth in remote nonischemic myocardium by Elmadhun, Nassrene Y., MD, Sabe, Ashraf A., MD, Lassaletta, Antonio D., MD, Sellke, Frank W., MD

“…Abstract Background Epidemiologic studies have demonstrated that daily low to moderate alcohol consumption is cardioprotective as compared with abstainers and…”
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Alcohol consumption improves insulin signaling in the myocardium by Elmadhun, Nassrene Y., MD, Lassaletta, Antonio D., MD, Burgess, Thomas, BS, Sabe, Ashraf A., MD, Sellke, Frank W., MD

“…Background In a previous study, we demonstrated that swine with metabolic syndrome treated with alcohol had improved insulin signaling. We developed a…”
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Vodka and wine consumption in a swine model of metabolic syndrome alters insulin signaling pathways in the liver and skeletal muscle by Elmadhun, Nassrene Y., MD, Lassaletta, Antonio D., MD, Chu, Louis M., MD, Bianchi, Cesario, MD, PhD, Sellke, Frank W., MD

“…Background The purpose of this study was to examine the effects of alcohol in the context of metabolic syndrome on insulin signaling pathways in the liver and…”
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Cardioprotective effects of red wine and vodka in a model of endothelial dysfunction by Lassaletta, Antonio D., MD, Chu, Louis M., MD, Elmadhun, Nassrene Y., MD, Burgess, Thomas A., MA, Feng, Jun, MD, PhD, Robich, Michael P., MD, Sellke, Frank W., MD

“…Abstract Background Moderate alcohol consumption is largely believed to be cardioprotective, while red wine is hypothesized to offer benefit in part due to the…”
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