Search Results - "Lassak, Jürgen"
-
1
Two RmlC homologs catalyze dTDP-4-keto-6-deoxy-d-glucose epimerization in Pseudomonas putida KT2440
Published in Scientific reports (07-06-2021)“…l -Rhamnose is an important monosaccharide both as nutrient source and as building block in prokaryotic glycoproteins and glycolipids. Generation of those…”
Get full text
Journal Article -
2
Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches
Published in Science (American Association for the Advancement of Science) (04-01-2013)“…Translation elongation factor P (EF-P) is critical for virulence in bacteria. EF-P is present in all bacteria and orthologous to archaeal and eukaryotic…”
Get full text
Journal Article -
3
ArcS, the Cognate Sensor Kinase in an Atypical Arc System of Shewanella oneidensis MR-1
Published in Applied and Environmental Microbiology (01-05-2010)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
4
Phage-induced lysis enhances biofilm formation in Shewanella oneidensis MR-1
Published in The ISME Journal (01-04-2011)“…Shewanella oneidensis MR-1 is capable of forming highly structured surface-attached communities. By DNase I treatment, we demonstrated that extracellular DNA…”
Get full text
Journal Article -
5
Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P
Published in Proceedings of the National Academy of Sciences - PNAS (17-09-2013)“…Ribosomes are the protein synthesizing factories of the cell, polymerizing polypeptide chains from their constituent amino acids. However, distinct…”
Get full text
Journal Article -
6
Evolutionary analysis of polyproline motifs in Escherichia coli reveals their regulatory role in translation
Published in PLoS computational biology (01-02-2018)“…Translation of consecutive prolines causes ribosome stalling, which is alleviated but cannot be fully compensated by the elongation factor P. However, the…”
Get full text
Journal Article -
7
Translational stalling at polyproline stretches is modulated by the sequence context upstream of the stall site
Published in Nucleic acids research (15-09-2014)“…The polymerization of amino acids into proteins occurs on ribosomes, with the rate influenced by the amino acids being polymerized. The imino acid proline is a…”
Get full text
Journal Article -
8
Arginine-rhamnosylation as new strategy to activate translation elongation factor P
Published in Nature chemical biology (01-04-2015)“…N -linked glycosylation of a conserved arginine in the translation elongation factor EF-P by a newly discovered rhamnosyltransferase EarP is needed to rescue…”
Get full text
Journal Article -
9
Bacterial transmembrane signalling systems and their engineering for biosensing
Published in Open biology (01-04-2018)“…Every living cell possesses numerous transmembrane signalling systems that receive chemical and physical stimuli from the environment and transduce this…”
Get full text
Journal Article -
10
Proline codon pair selection determines ribosome pausing strength and translation efficiency in bacteria
Published in Communications biology (17-05-2021)“…The speed of mRNA translation depends in part on the amino acid to be incorporated into the nascent chain. Peptide bond formation is especially slow with…”
Get full text
Journal Article -
11
A Versatile Toolbox for the Control of Protein Levels Using N ε‑Acetyl‑l‑lysine Dependent Amber Suppression
Published in ACS synthetic biology (20-10-2017)“…The analysis of the function of essential genes in vivo depends on the ability to experimentally modulate levels of their protein products. Current methods to…”
Get full text
Journal Article -
12
Identification and Initial Characterization of Prophages in Vibrio campbellii
Published in PloS one (23-05-2016)“…Phages are bacteria targeting viruses and represent the most abundant biological entities on earth. Marine environments are exceptionally rich in…”
Get full text
Journal Article -
13
Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator
Published in Scientific reports (21-04-2017)“…The transmembrane DNA-binding protein CadC of E. coli , a representative of the ToxR-like receptor family, combines input and effector domains for signal…”
Get full text
Journal Article -
14
La dolce vita — süße Übersetzungshilfe für Prolinfolgen
Published in Biospektrum (01-09-2018)Get full text
Journal Article -
15
Switching the Post-translational Modification of Translation Elongation Factor EF-P
Published in Frontiers in microbiology (24-05-2019)“…Tripeptides with two consecutive prolines are the shortest and most frequent sequences causing ribosome stalling. The bacterial translation elongation factor P…”
Get full text
Journal Article -
16
Structural Basis for EarP-Mediated Arginine Glycosylation of Translation Elongation Factor EF-P
Published in mBio (26-09-2017)“…Glycosylation is a universal strategy to posttranslationally modify proteins. The recently discovered arginine rhamnosylation activates the…”
Get full text
Journal Article -
17
Editorial overview: Linking cellular regulation and metabolic functions: from signals to mechanisms
Published in Current opinion in microbiology (01-08-2024)Get full text
Journal Article -
18
A Conserved Proline Triplet in Val-tRNA Synthetase and the Origin of Elongation Factor P
Published in Cell reports (Cambridge) (23-10-2014)“…Bacterial ribosomes stall on polyproline stretches and require the elongation factor P (EF-P) to relieve the arrest. Yet it remains unclear why evolution has…”
Get full text
Journal Article -
19
Domain Analysis of ArcS, the Hybrid Sensor Kinase of the Shewanella oneidensis MR-1 Arc Two-Component System, Reveals Functional Differentiation of Its Two Receiver Domains
Published in Journal of Bacteriology (01-02-2013)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
20
Analysis of the BarA/UvrY two-component system in Shewanella oneidensis MR-1
Published in PloS one (12-09-2011)“…The BarA/UvrY two-component system is well conserved in species of the γ-proteobacteria and regulates numerous processes predominantly by controlling the…”
Get full text
Journal Article