Search Results - "Lassak, Jürgen"

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  1. 1

    Two RmlC homologs catalyze dTDP-4-keto-6-deoxy-d-glucose epimerization in Pseudomonas putida KT2440 by Koller, Franziska, Lassak, Jürgen

    Published in Scientific reports (07-06-2021)
    “…l -Rhamnose is an important monosaccharide both as nutrient source and as building block in prokaryotic glycoproteins and glycolipids. Generation of those…”
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  2. 2

    Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches by Ude, Susanne, Lassak, Jürgen, Starosta, Agata L., Kraxenberger, Tobias, Wilson, Daniel N., Jung, Kirsten

    “…Translation elongation factor P (EF-P) is critical for virulence in bacteria. EF-P is present in all bacteria and orthologous to archaeal and eukaryotic…”
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  3. 3

    ArcS, the Cognate Sensor Kinase in an Atypical Arc System of Shewanella oneidensis MR-1 by LASSAK, Jürgen, HENCHE, Anna-Lena, BINNENKADE, Lucas, THORMANN, Kai M

    Published in Applied and Environmental Microbiology (01-05-2010)
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  4. 4

    Phage-induced lysis enhances biofilm formation in Shewanella oneidensis MR-1 by Gödeke, Julia, Paul, Kristina, Lassak, Jürgen, Thormann, Kai M

    Published in The ISME Journal (01-04-2011)
    “…Shewanella oneidensis MR-1 is capable of forming highly structured surface-attached communities. By DNase I treatment, we demonstrated that extracellular DNA…”
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  5. 5

    Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P by Peil, Lauri, Starosta, Agata L., Lassak, Jürgen, Atkinson, Gemma, Virumäe, Kai, Spitzer, Michaela, Tenson, Tanel, Jung, Kirsten, Remme, Jaanus, Wilson, Daniel N.

    “…Ribosomes are the protein synthesizing factories of the cell, polymerizing polypeptide chains from their constituent amino acids. However, distinct…”
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  6. 6

    Evolutionary analysis of polyproline motifs in Escherichia coli reveals their regulatory role in translation by Qi, Fei, Motz, Magdalena, Jung, Kirsten, Lassak, Jürgen, Frishman, Dmitrij

    Published in PLoS computational biology (01-02-2018)
    “…Translation of consecutive prolines causes ribosome stalling, which is alleviated but cannot be fully compensated by the elongation factor P. However, the…”
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  7. 7

    Translational stalling at polyproline stretches is modulated by the sequence context upstream of the stall site by Starosta, Agata L, Lassak, Jürgen, Peil, Lauri, Atkinson, Gemma C, Virumäe, Kai, Tenson, Tanel, Remme, Jaanus, Jung, Kirsten, Wilson, Daniel N

    Published in Nucleic acids research (15-09-2014)
    “…The polymerization of amino acids into proteins occurs on ribosomes, with the rate influenced by the amino acids being polymerized. The imino acid proline is a…”
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  8. 8

    Arginine-rhamnosylation as new strategy to activate translation elongation factor P by Lassak, Jürgen, Keilhauer, Eva C, Fürst, Maximilian, Wuichet, Kristin, Gödeke, Julia, Starosta, Agata L, Chen, Jhong-Min, Søgaard-Andersen, Lotte, Rohr, Jürgen, Wilson, Daniel N, Häussler, Susanne, Mann, Matthias, Jung, Kirsten

    Published in Nature chemical biology (01-04-2015)
    “…N -linked glycosylation of a conserved arginine in the translation elongation factor EF-P by a newly discovered rhamnosyltransferase EarP is needed to rescue…”
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  9. 9

    Bacterial transmembrane signalling systems and their engineering for biosensing by Jung, Kirsten, Fabiani, Florian, Hoyer, Elisabeth, Lassak, Jürgen

    Published in Open biology (01-04-2018)
    “…Every living cell possesses numerous transmembrane signalling systems that receive chemical and physical stimuli from the environment and transduce this…”
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  10. 10

    Proline codon pair selection determines ribosome pausing strength and translation efficiency in bacteria by Krafczyk, Ralph, Qi, Fei, Sieber, Alina, Mehler, Judith, Jung, Kirsten, Frishman, Dmitrij, Lassak, Jürgen

    Published in Communications biology (17-05-2021)
    “…The speed of mRNA translation depends in part on the amino acid to be incorporated into the nascent chain. Peptide bond formation is especially slow with…”
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  11. 11

    A Versatile Toolbox for the Control of Protein Levels Using N ε‑Acetyl‑l‑lysine Dependent Amber Suppression by Volkwein, Wolfram, Maier, Christopher, Krafczyk, Ralph, Jung, Kirsten, Lassak, Jürgen

    Published in ACS synthetic biology (20-10-2017)
    “…The analysis of the function of essential genes in vivo depends on the ability to experimentally modulate levels of their protein products. Current methods to…”
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  12. 12

    Identification and Initial Characterization of Prophages in Vibrio campbellii by Lorenz, Nicola, Reiger, Matthias, Toro-Nahuelpan, Mauricio, Brachmann, Andreas, Poettinger, Lisa, Plener, Laure, Lassak, Jürgen, Jung, Kirsten

    Published in PloS one (23-05-2016)
    “…Phages are bacteria targeting viruses and represent the most abundant biological entities on earth. Marine environments are exceptionally rich in…”
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  13. 13

    Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator by Schlundt, Andreas, Buchner, Sophie, Janowski, Robert, Heydenreich, Thomas, Heermann, Ralf, Lassak, Jürgen, Geerlof, Arie, Stehle, Ralf, Niessing, Dierk, Jung, Kirsten, Sattler, Michael

    Published in Scientific reports (21-04-2017)
    “…The transmembrane DNA-binding protein CadC of E. coli , a representative of the ToxR-like receptor family, combines input and effector domains for signal…”
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  14. 14
  15. 15

    Switching the Post-translational Modification of Translation Elongation Factor EF-P by Volkwein, Wolfram, Krafczyk, Ralph, Jagtap, Pravin Kumar Ankush, Parr, Marina, Mankina, Elena, Macošek, Jakub, Guo, Zhenghuan, Fürst, Maximilian Josef Ludwig Johannes, Pfab, Miriam, Frishman, Dmitrij, Hennig, Janosch, Jung, Kirsten, Lassak, Jürgen

    Published in Frontiers in microbiology (24-05-2019)
    “…Tripeptides with two consecutive prolines are the shortest and most frequent sequences causing ribosome stalling. The bacterial translation elongation factor P…”
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  16. 16

    Structural Basis for EarP-Mediated Arginine Glycosylation of Translation Elongation Factor EF-P by Krafczyk, Ralph, Macošek, Jakub, Jagtap, Pravin Kumar Ankush, Gast, Daniel, Wunder, Swetlana, Mitra, Prithiba, Jha, Amit Kumar, Rohr, Jürgen, Hoffmann-Röder, Anja, Jung, Kirsten, Hennig, Janosch, Lassak, Jürgen

    Published in mBio (26-09-2017)
    “…Glycosylation is a universal strategy to posttranslationally modify proteins. The recently discovered arginine rhamnosylation activates the…”
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  18. 18

    A Conserved Proline Triplet in Val-tRNA Synthetase and the Origin of Elongation Factor P by Starosta, Agata L., Lassak, Jürgen, Peil, Lauri, Atkinson, Gemma C., Woolstenhulme, Christopher J., Virumäe, Kai, Buskirk, Allen, Tenson, Tanel, Remme, Jaanus, Jung, Kirsten, Wilson, Daniel N.

    Published in Cell reports (Cambridge) (23-10-2014)
    “…Bacterial ribosomes stall on polyproline stretches and require the elongation factor P (EF-P) to relieve the arrest. Yet it remains unclear why evolution has…”
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  19. 19

    Domain Analysis of ArcS, the Hybrid Sensor Kinase of the Shewanella oneidensis MR-1 Arc Two-Component System, Reveals Functional Differentiation of Its Two Receiver Domains by Lassak, Jürgen, Bubendorfer, Sebastian, Thormann, Kai M

    Published in Journal of Bacteriology (01-02-2013)
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  20. 20

    Analysis of the BarA/UvrY two-component system in Shewanella oneidensis MR-1 by Binnenkade, Lucas, Lassak, Jürgen, Thormann, Kai M

    Published in PloS one (12-09-2011)
    “…The BarA/UvrY two-component system is well conserved in species of the γ-proteobacteria and regulates numerous processes predominantly by controlling the…”
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