Search Results - "Laslett, L. L."

The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study by Cross, Marita, Smith, Emma, Hoy, Damian, Nolte, Sandra, Ackerman, Ilana, Fransen, Marlene, Bridgett, Lisa, Williams, Sean, Guillemin, Francis, Hill, Catherine L, Laslett, Laura L, Jones, Graeme, Cicuttini, Flavia, Osborne, Richard, Vos, Theo, Buchbinder, Rachelle, Woolf, Anthony, March, Lyn

“…To estimate the global burden of hip and knee osteoarthritis (OA) as part of the Global Burden of Disease 2010 study and to explore how the burden of hip and…”
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A randomised double-blind placebo-controlled crossover trial of HUMira (adalimumab) for erosive hand OsteoaRthritis – the HUMOR trial by Aitken, D., Laslett, L.L., Pan, F., Haugen, I.K., Otahal, P., Bellamy, N., Bird, P., Jones, G.

“…To assess the efficacy of adalimumab in patients with erosive hand osteoarthritis (OA). Patients >50 years old, meeting the American College of Rheumatology…”
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KARAOKE: Krill oil versus placebo in the treatment of knee osteoarthritis: protocol for a randomised controlled trial by Laslett, L L, Antony, B, Wluka, A E, Hill, C, March, L, Keen, H I, Otahal, P, Cicuttini, F M, Jones, G

“…Knee osteoarthritis (OA) is a common and important cause of pain and disability, but interventions aimed at modifying structures visible on imaging have been…”
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Cut-points for associations between vitamin D status and multiple musculoskeletal outcomes in middle-aged women by Wu, F., Wills, K., Laslett, L. L., Oldenburg, B., Seibel, M. J., Jones, G., Winzenberg, T.

“…Summary This was the first study examining optimal vitamin D status for musculoskeletal health in middle-aged women. A 25-hydroxyvitamin D level of at least 29…”
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The effects of microgravity on bone structure and function by Man, Joey, Graham, Taylor, Squires-Donelly, Georgina, Laslett, Andrew L.

“…Humans are spending an increasing amount of time in space, where exposure to conditions of microgravity causes 1–2% bone loss per month in astronauts. Through…”
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Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming by Liu, Xiaodong, Nefzger, Christian M, Rossello, Fernando J, Chen, Joseph, Knaupp, Anja S, Firas, Jaber, Ford, Ethan, Pflueger, Jahnvi, Paynter, Jacob M, Chy, Hun S, O'Brien, Carmel M, Huang, Cheng, Mishra, Ketan, Hodgson-Garms, Margeaux, Jansz, Natasha, Williams, Sarah M, Blewitt, Marnie E, Nilsson, Susan K, Schittenhelm, Ralf B, Laslett, Andrew L, Lister, Ryan, Polo, Jose M

“…This study compares naive human pluripotent stem cells, either reprogrammed directly from somatic cells or converted from primed cells, under a variety of…”
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Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ESCs and iPSCs during Reprogramming and Time in Culture by Laurent, Louise C., Ulitsky, Igor, Slavin, Ileana, Tran, Ha, Schork, Andrew, Morey, Robert, Lynch, Candace, Harness, Julie V., Lee, Sunray, Barrero, Maria J., Ku, Sherman, Martynova, Marina, Semechkin, Ruslan, Galat, Vasiliy, Gottesfeld, Joel, Belmonte, Juan Carlos Izpisua, Murry, Chuck, Keirstead, Hans S., Park, Hyun-Sook, Schmidt, Uli, Laslett, Andrew L., Muller, Franz-Josef, Nievergelt, Caroline M., Shamir, Ron, Loring, Jeanne F.

“…Genomic stability is critical for the clinical use of human embryonic and induced pluripotent stem cells. We performed high-resolution SNP (single-nucleotide…”
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Improving telehealth for persons with multiple sclerosis - a cross-sectional study from the Australian MS longitudinal study by Learmonth, Y C, Galna, B, Laslett, L L, van der Mei, I, Marck, C H

“…The COVID-19 pandemic impacted healthcare delivery, especially for people with chronic disease. We investigated telehealth use by persons with multiple…”
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A continuum of cell states spans pluripotency and lineage commitment in human embryonic stem cells by Hough, Shelley R, Laslett, Andrew L, Grimmond, Sean B, Kolle, Gabriel, Pera, Martin F

“…Commitment in embryonic stem cells is often depicted as a binary choice between alternate cell states, pluripotency and specification to a particular germ…”
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The Cost of Osteoporosis, Osteopenia, and Associated Fractures in Australia in 2017 by Tatangelo, Gemma, Watts, Jennifer, Lim, Karen, Connaughton, Catherine, Abimanyi‐Ochom, Julie, Borgström, Fredrik, Nicholson, Geoff C, Shore‐Lorenti, Catherine, Stuart, Amanda L, Iuliano‐Burns, Sandra, Seeman, Ego, Prince, Richard, March, Lyn, Cross, Marita, Winzenberg, Tania, Laslett, Laura L, Duque, Gustavo, Ebeling, Peter R, Sanders, Kerrie M

“…ABSTRACT Osteoporosis and osteopenia are increasingly prevalent conditions among older adults. Not only do the fractures associated with poor bone health have…”
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Cell surface markers for the identification and study of human naive pluripotent stem cells by Trusler, Oliver, Huang, Ziyi, Goodwin, Jacob, Laslett, Andrew L.

“…Characterisation of mouse pluripotent stem cells has revealed two distinct pluripotent states, naive and primed, that maintain characteristics of the pre and…”
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Changes in quality of life associated with fragility fractures: Australian arm of the International Cost and Utility Related to Osteoporotic Fractures Study (AusICUROS) by Abimanyi-Ochom, J., Watts, J. J., Borgström, F., Nicholson, G. C., Shore-Lorenti, C., Stuart, A. L., Zhang, Y., Iuliano, S., Seeman, E., Prince, R., March, L., Cross, M., Winzenberg, T., Laslett, L. L., Duque, G., Ebeling, P. R., Sanders, K. M.

“…Summary We investigated change in health-related quality of life due to fracture in Australian adults aged over 50 years. Fractures reduce quality of life with…”
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The directed differentiation of human iPS cells into kidney podocytes by Song, Bi, Smink, Alexandra M, Jones, Christina V, Callaghan, Judy M, Firth, Stephen D, Bernard, Claude A, Laslett, Andrew L, Kerr, Peter G, Ricardo, Sharon D

“…The loss of glomerular podocytes is a key event in the progression of chronic kidney disease resulting in proteinuria and declining function. Podocytes are…”
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Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and Their Differentiated Derivatives by Nazor, Kristopher L., Altun, Gulsah, Lynch, Candace, Tran, Ha, Harness, Julie V., Slavin, Ileana, Garitaonandia, Ibon, Müller, Franz-Josef, Wang, Yu-Chieh, Boscolo, Francesca S., Fakunle, Eyitayo, Dumevska, Biljana, Lee, Sunray, Park, Hyun Sook, Olee, Tsaiwei, D'Lima, Darryl D., Semechkin, Ruslan, Parast, Mana M., Galat, Vasiliy, Laslett, Andrew L., Schmidt, Uli, Keirstead, Hans S., Loring, Jeanne F., Laurent, Louise C.

“…Human pluripotent stem cells (hPSCs) are potential sources of cells for modeling disease and development, drug discovery, and regenerative medicine. However,…”
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Effect of Zoledronic Acid and Denosumab in Patients With Low Back Pain and Modic Change: A Proof‐of‐Principle Trial by Cai, Guoqi, Laslett, Laura L, Aitken, Dawn, Halliday, Andrew, Pan, Feng, Otahal, Petr, Speden, Deborah, Winzenberg, Tania M, Jones, Graeme

“…ABSTRACT The aim of this study was to evaluate the effect of zoledronic acid (ZA) and denosumab on low back pain (LBP) and Modic change (MC) over 6 months…”
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The association between incident vertebral deformities, health-related quality of life and functional impairment: a 10.7-year cohort study by Shah, A., Wu, F., Jones, G., Cicuttini, F., Toh, L.S., Laslett, L.L.

“…Summary We aimed to describe longitudinal changes in health-related quality of life (HRQoL) measures associated with incident vertebral deformities (VDs) over…”
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A protocol for a multicentre, randomised, double-blind, placebo-controlled trial to compare the effect of annual infusions of zoledronic acid to placebo on knee structural change and knee pain over 24 months in knee osteoarthritis patients - ZAP2 by Aitken, Dawn, Laslett, Laura L, Cai, Guoqi, Hill, Catherine, March, Lyn, Wluka, Anita E, Wang, Yuanyuan, Blizzard, Leigh, Cicuttini, Flavia, Jones, Graeme

“…Bisphosphonates are a class of drugs that slow bone loss and are a promising candidate to treat knee osteoarthritis (OA) patients. In a pilot study, we…”
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Protocol for a pragmatic randomised controlled feasibility study of MS WorkSmart: an online intervention for Australians with MS who are employed by van der Mei, Ingrid, Thomas, Sarah, Shapland, Sue, Laslett, Laura L, Taylor, Bruce V, Huglo, Alisée, Honan, Cynthia

“…IntroductionMultiple sclerosis (MS) causes a wide variety of symptoms. Loss of income due to sickness and early retirement comprise one-third of the total cost…”
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Once-yearly zoledronic acid and change in abdominal aortic calcification over 3 years in postmenopausal women with osteoporosis: results from the HORIZON Pivotal Fracture Trial by Cai, G., Keen, H. I., Host, L. V., Aitken, D., Laslett, L. L., Winzenberg, T., Wluka, A. E., Black, D., Jones, G.

“…Summary This study evaluated whether zoledronic acid (ZA) inhibited the progression of abdominal aortic calcification (AAC) over 3 years in 502 postmenopausal…”
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Comparison of radiographic and MRI osteoarthritis definitions and their combination for prediction of tibial cartilage loss, knee symptoms and total knee replacement: a longitudinal study by Cai, G., Cicuttini, F., Aitken, D., Laslett, L.L., Zhu, Z., Winzenberg, T., Jones, G.

“…To describe the value of radiographic- and magnetic resonance imaging (MRI)-defined tibiofemoral osteoarthritis (ROA and MRI-OA, respectively) and in…”
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