Search Results - "Lasky, Larry C."

Prolonged continuous in vitro human platelet production using three-dimensional scaffolds by Sullenbarger, Brent, Bahng, Joong Hwan, Gruner, Ryan, Kotov, Nicholas, Lasky, Larry C

“…Objective Methods producing human platelets using growth on plastic, on feeder layers, or in suspension have been described. We hypothesized that growth of…”
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Precancerous stem cells have the potential for both benign and malignant differentiation by Chen, Li, Shen, Rulong, Ye, Yin, Pu, Xin-An, Liu, Xingluo, Duan, Wenrui, Wen, Jing, Zimmerer, Jason, Wang, Ying, Liu, Yan, Lasky, Larry C, Heerema, Nyla A, Perrotti, Danilo, Ozato, Keiko, Kuramochi-Miyagawa, Satomi, Nakano, Toru, Yates, Allen J, Carson, 3rd, William E, Lin, Haifan, Barsky, Sanford H, Gao, Jian-Xin

“…Cancer stem cells (CSCs) have been identified in hematopoietic and solid tumors. However, their precursors-namely, precancerous stem cells (pCSCs) -have not…”
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In utero or ex utero cord blood collection: which is better? by Lasky, Larry C., Lane, Thomas A., Miller, John P., Lindgren, Bruce, Patterson, Heidi A., Haley, N. Rebecca, Ballen, Karen

“…BACKGROUND : The relative nucleated cell count of umbilical cord blood (CB) correlates with improved engraftment and survival. This study compares two…”
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Characterization of antibody binding to three cancer-related antigens using flow cytometry and cell tracking velocimetry by Chosy, E. Julia, Nakamura, Masayuki, Melnik, Kristie, Comella, Kristin, Lasky, Larry C., Zborowski, Maciej, Chalmers, Jeffrey J.

“…Proper antibody labeling is a fundamental step in the positive selection/isolation of rare cancer cells using immunomagnetic cell separation technology. Using…”
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Manipulation of oxygenation and flow-induced shear stress can increase the in vitro yield of platelets from cord blood by Lasky, Larry C, Sullenbarger, Brent

“…A method to produce clinically useful platelets in vitro would help overcome the frequent shortages, donor deferrals, disease transmission, and…”
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Culturing and differentiation of murine embryonic stem cells in a three-dimensional fibrous matrix by YAN LI, KNISS, Douglas A, LASKY, Larry C, YANG, Shang-Tian

“…Embryonic stem (ES) cells have indefinite self-renewal ability and pluripotency, and can provide a novel cell source for tissue engineering applications. In…”
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Effect of increased HoxB4 on human megakaryocytic development by Zhong, Yiming, Sullenbarger, Brent, Lasky, Larry C.

“…► HoxB4 overexpression in human TF1 cells increased the expression of CD61 and CD41a. ► HoxB4 fusion protein enhanced megakaryocytic development of CD34 + cord…”
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Effects of Filtration Seeding on Cell Density, Spatial Distribution, and Proliferation in Nonwoven Fibrous Matrices by Li, Yan, Ma, Teng, Kniss, Douglas A., Lasky, Larry C., Yang, Shang-Tian

“…The cell seeding density and spatial distribution in a 3‐D scaffold are critical to the morphogenetic development of an engineered tissue. A dynamic…”
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Diaspirin-Crosslinked Hemoglobin Reduces Blood Transfusion in Noncardiac Surgery: A Multicenter, Randomized, Controlled, Double-Blinded Trial by Schubert, Armin, Przybelski, Robert J., Eidt, John F., Lasky, Larry C., Marks, Kenneth E., Karafa, Matthew, Novick, Andrew C., O’Hara, Jerome F., Saunders, Michael E., Blue, John W., Tetzlaff, John E., Mascha, Edward

“…In this randomized, prospective, double-blinded clinical trial, we sought to investigate whether diaspirin-crosslinked hemoglobin (DCLHb) can reduce the…”
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Transgene expression after stable transfer of a mammalian artificial chromosome into human hematopoietic cells by Vanderbyl, Sandra L., Sullenbarger, Brent, White, Nicole, Perez, Carl F., MacDonald, G. Neil, Stodola, Tom, Bunnell, Bruce A., Ledebur, Harry C., Lasky, Larry C.

“…The transfer of mammalian artificial chromosomes (MACs) to hematopoietic stem and progenitor cells (HSPCs) presents a promising new strategy for ex vivo gene…”
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346. The ACE System, a Mammalian Artificial Chromosome Engineering Technology: Delivery and Transgene Expression in Human Adult & Embryonic Stem Cells by Vanderbyl, Sandra L., Sullenbarger, Brent, MacDonald, Neil, Golembiewski, Melanie, Perez, Carl F., Ledebur Jr, Harry C., Lasky, Larry C.

“…The ACE System is a potent biological engineering system consisting of a mammalian artificial chromosome engineered with multiple site-specific integration…”
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Separation of a Breast Cancer Cell Line from Human Blood Using a Quadrupole Magnetic Flow Sorter by Nakamura, Masayuki, Decker, Keith, Chosy, Julia, Comella, Kristin, Melnik, Kristie, Moore, Lee, Lasky, Larry C., Zborowski, Maciej, Chalmers, Jeffrey J.

“…We have developed a quadrupole magnetic flow sorter (QMS) to facilitate high‐throughput binary cell separation. Optimized QMS operation requires the adjustment…”
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Prognostic significance of morphologic parameters in renal cell carcinoma by Fuhrman, S A, Lasky, L C, Limas, C

“…The prognostic significance of morphologic parameters was evaluated in 103 patients with renal cell carcinoma diagnosed during 1961--1974. Pathologic material…”
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Human cord cell hematopoiesis in three-dimensional nonwoven fibrous matrices: in vitro simulation of the marrow microenvironment by Li, Y, Ma, T, Kniss, D A, Yang, S T, Lasky, L C

“…Current hematopoietic culture systems mainly utilize two-dimensional devices with limited ability to promote self-renewal of early progenitors. In vivo-like…”
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Epoetin enhances erythropoiesis in normal men undergoing repeated phlebotomies by Abraham, P A, Halstenson, C E, Macres, M M, Opsahl, J A, Rank, B H, Schwenk, M H, Lasky, L C, Cohen, A, Lasseter, K C, Smith, D L

“…Epoetin may enhance autologous blood donation, but efficacy and dose response have not been established. This multicenter, double-blind trial compared…”
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Prolonged Continuous In Vitro Human Platelet Production Using 3D Scaffolds by Sullenbarger, Brent, Hwan Bahng, Joong, Gruner, Ryan, Kotov, Nicholas, Lasky, Larry C.

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Reply by Lasky, Larry C., Haley, N. Rebecca, Ballen, Karen Kuhn

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Reply by Lasky, Larry C., Haley, N. Rebecca, Ballen, Karen Kuhn

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Reply: The above letter was sent to Lasky et al.; Dr Lasky offered the following reply by Lasky, Larry C., Haley, N. Rebecca, Ballen, Karen Kuhn

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Precancerous stem cells have the potential for both benign and malignant differentiation by Chen, Li, Shen, Rulong, Duan, Wen‐Rui, Liu, Xingluo, Wen, Jing, Liu, Yan, Wang, Yin, Lasky, Larry C, Perrotti, Danilo, Lin, Hai‐Fan, Gao, Jian‐Xin

“…Cancer stem cells (CSCs) may be derived from normal stem cells through a precancerous stage, during which stem cells are hierarchically disturbed in their…”
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