Search Results - "Laskowitz, D.T."

Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease by Dawson, H.N, Cantillana, V, Jansen, M, Wang, H, Vitek, M.P, Wilcock, D.M, Lynch, J.R, Laskowitz, D.T

“…Abstract A central issue in the pathogenesis of tauopathy is the question of how tau protein dysfunction leads to neurodegeneration. We have previously…”
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An apolipoprotein E-based therapeutic improves outcome and reduces Alzheimer’s disease pathology following closed head injury: Evidence of pharmacogenomic interaction by Wang, H, Durham, L, Dawson, H, Song, P, Warner, D.S, Sullivan, P.M, Vitek, M.P, Laskowitz, D.T

“…Abstract Apolipoprotein E (apoE) modifies glial activation and the CNS inflammatory response in an isoform-specific manner. Peptides derived from the…”
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Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response by Lynch, J.R., Morgan, D., Mance, J., Matthew, W.D., Laskowitz, D.T.

“…Apolipoprotein E (apoE) is a 299 amino acid protein that is associated with risk of developing Alzheimer’s Disease (AD) and outcome after acute brain injury…”
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Downregulation of Microglial Activation by Apolipoprotein E and ApoE-Mimetic Peptides by Laskowitz, D.T., Thekdi, A.D., Thekdi, S.D., Han, S.K.D., Myers, J.K., Pizzo, S.V., Bennett, E.R.

“…Apolipoprotein E plays an important role in recovery from acute brain injury and risk of developing Alzheimer's disease. We demonstrate that biologically…”
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270: C-reactive Protein as a Serum Biomarker in the Evaluation of Patients With Minor Head Injury and Normal Mental Status in the Emergency Department by Phillips, S, Glickman, S.W, Stanley, L.J, Preston, R.J, Grant, G.A, Laskowitz, D.T, Cairns, C.B

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Corrigendum to “an apolipoprotein e-based therapeutic improves outcome and reduces alzheimer’s disease pathology following closed head injury: Evidence of pharmacogenomic interaction” by Wang, H, Durham, L, Dawson, H, Song, P, Warner, D.S, Sullivan, P.M, Vitek, M.P, Laskowitz, D.T

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Altered immune responses in apolipoprotein E-deficient mice by Laskowitz, D T, Lee, D M, Schmechel, D, Staats, H F

“…Apolipoprotein E (apoE) is a 34 kDa glycosylated protein with multiple biological properties. In addition to its role in cholesterol transport, apoE has in…”
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ANTIDOTE REVERSAL OF A NOVEL ANTICOAGULANT DECREASES MORTALITY AND IMPROVES NEUROLOGICAL FUNCTION IN A MURINE MODEL OF SUBARACHNOID HEMORRHAGE by Blake, C.M., Wang, H., Laskowitz, D.T., Sullenger, B.A.

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APOE genotype affects outcome in a murine model of sepsis : implications for a new treatment strategy by WANG, H, CHRISTENSEN, D. J, VITEK, M. P, SULLIVAN, P. M, LASKOWITZ, D. T

“…In this study, we assessed whether apolipoprotein E (APOE) polymorphism affects inflammatory responses and mortality in the caecal ligation and puncture model…”
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Protective effect of apolipoprotein E-mimetic peptides on N-methyl- d-aspartate excitotoxicity in primary rat neuronal–glial cell cultures by Aono, M, Bennett, E.R, Kim, K.S, Lynch, J.R, Myers, J, Pearlstein, R.D, Warner, D.S, Laskowitz, D.T

“…Apolipoprotein E (apoE) is a 34-kD protein with multiple biological properties. Recent clinical and preclinical observations implicate a role for apoE in…”
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Apolipoprotein E suppresses glial cell secretion of TNF α by Laskowitz, D.T, Goel, S, Bennett, E.R, Matthew, W.D

“…Apolipoprotein E (apoE) is a 299 amino acid protein with multiple biological functions. Initially described in the context of cholesterol metabolism, apoE also…”
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Survival and outcome after endotracheal intubation for acute stroke by BUSHNELL, C. D, PHILLIPS-BUTE, B. G, LASKOWITZ, D. T, LYNCH, J. R, CHILUKURI, V, BOREL, C. O

“…To assess survival and functional outcome in patients endotracheally intubated after ischemic stroke (IS) or spontaneous intracerebral hemorrhage (ICH)…”
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7A-5 Real-Time 3D Contrast-Enhanced Transcranial Ultrasound by Ivancevich, N.M., Pinton, G.F., Smith, S.W., Nicoletto, H.A., Scism, M., Bennett, E., Laskowitz, D.T.

“…Contrast-enhanced (CE) transcranial ultrasound (US) and reconstructed 3D transcranial ultrasound have shown advantages over traditional methods in a variety of…”
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The ultrasound brain helmet for 3D transcranial Doppler imaging by Lindsey, B.D., Ivancevich, N.M., Light, E.D., Smith, S.W., Nicoletto, H.A., Bennett, E., Laskowitz, D.T.

“…Transcranial Doppler imaging with contrast enhancement is a promising approach for visualizing a variety of cerebrovascular diseases requiring rapid treatment…”
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2B-2 Phase Aberration Correction on a 3D Ultrasound Scanner Using RF Speckle from Moving Targets by Ivancevich, N.M., Dahl, J.D., Light, E.D., Nicoletto, H.A., Seism, M., Laskowitz, D.T., Trahey, G.E., Smith, S.W.

“…In 1992, Zhao et al. described a variation of the speckle-brightness algorithm for phase correction on moving targets [Zhao et al., 1992 and Bohs et al.,…”
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