Search Results - "Lash, Gendie"

The Role of Decidual Macrophages During Normal and Pathological Pregnancy by Ning, Fen, Liu, Huishu, Lash, Gendie E.

“…Macrophages perform many specific functions including host defense, homeostasis, angiogenesis, and tissue development. Macrophages are the second most abundant…”
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Role of osteopontin (OPN) in uterine spiral artery remodeling by Pan, Yue, Chen, Miaojuan, Lash, Gendie E.

“…Uterine spiral artery (SpA) remodeling is critical for a successful pregnancy. The deficiency of SpA remodeling seriously affects the blood perfusion of the…”
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Molecular Cross-Talk at the Feto-Maternal Interface by Lash, Gendie E

“…Molecular cross-talk at the feto-maternal interface occurs between many different cell types, including uterine leukocytes, extravillous trophoblast cells, and…”
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Contribution of vascular smooth muscle cell apoptosis to spiral artery remodeling in early human pregnancy by Liu, Hanbo, Ning, Fen, Lash, Gendie E.

“…Uterine spiral artery remodeling is one of the key maternal adaptations of pregnancy, allowing delivery of the large volumes of maternal blood required for…”
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CircRNA-0004904, CircRNA-0001855, and PAPP-A: Potential Novel Biomarkers for the Prediction of Preeclampsia by Jiang, Min, Lash, Gendie E., Zhao, Xueqing, Long, Yan, Guo, Caijiao, Yang, Hongling

“…Background/Aims: Circular RNAs (circRNAs) are transcribed prevalently in the genome; however, their potential roles in multiple cardiovascular diseases,…”
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Unraveling the mysteries of spiral artery remodeling by Zhang, Lindong, Liu, Jing, Feng, Xiaoqian, Lash, Gendie E.

“…Spiral artery remodeling is the process by which the uterine vessels become large bore low resistance conduits, allowing delivery of high volumes of maternal…”
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The human fetal placenta promotes tolerance against the semiallogeneic fetus by inducing regulatory T cells and homeostatic M2 macrophages by Svensson-Arvelund, Judit, Mehta, Ratnesh B, Lindau, Robert, Mirrasekhian, Elahe, Rodriguez-Martinez, Heriberto, Berg, Göran, Lash, Gendie E, Jenmalm, Maria C, Ernerudh, Jan

“…A successful pregnancy requires that the maternal immune system is instructed to a state of tolerance to avoid rejection of the semiallogeneic fetal-placental…”
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Oxidative stress drives endometrial fibrosis via TGF‐β1/MAPK signaling pathway in breast cancer by Chen, Hui, Wang, Minghua, Zhang, Zhejun, Lin, Fangfang, Guo, Bihui, Lu, Qinsheng, Lash, Gendie E., Li, Ping

“…Breast cancer patients have high serum reactive oxygen species (ROS) levels, which exert toxicity on the ovary. However, it is still unclear whether…”
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Editorial: Immune involvement in recurrent pregnancy loss by Lash, Gendie E, Raghupathy, Raj

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Decidual cytokines and pregnancy complications: focus on spontaneous miscarriage by Lash, Gendie E, Ernerudh, Jan

“…Highlights • Background to decidual cytokines and miscarriage. • Background to trophoblast invasion, spiral artery remodelling and immune tolerance. •…”
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Angiopoietin 2 in placentation and tumor biology: The yin and yang of vascular biology by Wang, Qiong, Lash, Gendie E

“…Abstract There are several parallels between placental and tumor biology. Both require rapid acquisition of a blood supply to supply oxygen and nutrients, the…”
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Decidual macrophages: key regulators of vascular remodeling in human pregnancy by Lash, Gendie E., Pitman, Hedele, Morgan, Hannah L., Innes, Barbara A., Agwu, Chinedu N., Bulmer, Judith N.

“…Decidual macrophages phagocytose apoptotic VSMC during remodeling of the uterine spiral arteries during early human pregnancy. Successful remodeling of the…”
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SIRT1 regulates trophoblast senescence in premature placental aging in preeclampsia by Wang, YuJia, Zhang, Yingye, Wu, Yongqi, He, Yunbiao, Xiang, Jingwen, Huang, Jieqiong, Lash, Gendie E., Li, Ping

“…Premature placental aging is implicated in a number of complications of pregnancy including preeclampsia. A placenta knockout mouse model has shown a…”
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Garcinol inhibits the proliferation of endometrial cancer cells by inducing cell cycle arrest by Zhang, Min, Lu, Qinsheng, Hou, Huomei, Sun, Dingqian, Chen, Miaojuan, Ning, Fen, Wu, Peihuang, Wei, Dan, Duan, Yaoyun, Pan, Yue, Lash, Gendie E

“…Endometrial cancer (EC) is the most common gynecological cancer, and one of the most important causes of cancer‑related deaths in women worldwide. The…”
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Editorial: Advances in research on aging in female infertility and pathologic pregnancy by Liu, Bin, Lash, Gendie, Wei, Fengxiang, Pantham, Priyadarshini

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Uterine natural killer cells initiate spiral artery remodeling in human pregnancy by Robson, Andrew, Harris, Lynda K., Innes, Barbara A., Lash, Gendie E., Aljunaidy, Mais M., Aplin, John D., Baker, Philip N., Robson, Stephen C., Bulmer, Judith N.

“…Uterine spiral artery remodeling is required for successful human pregnancy; impaired remodeling is associated with pregnancy complications, including late…”
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Tumor-Derived Oxidative Stress Triggers Ovarian Follicle Loss in Breast Cancer by Wu, Yongqi, Huang, Jieqiong, Chen, Hui, Tao, Huan, He, Yunbiao, Yang, Guang, Zha, Qingbing, Lash, Gendie E., Li, Ping

“…Breast cancer is a common indication for ovarian cryopreservation. However, whether the grafting ovarian tissue meets functional requirements, as well as the…”
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Extravillous trophoblast invasion and decidualization in cesarean scar pregnancies by Gao, Lufen, Chen, Hui, Liu, Jing, Wang, Minghua, Lin, Fangfang, Yang, Guang, Lash, Gendie E., Li, Ping

“…Introduction The increasing cesarean section rate has led to an increase in the number of subsequent pregnancies resulting in a cesarean scar pregnancy. There…”
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Cytochrome c oxidase IV isoform 1 (COX4-1) regulates the proliferation, migration and invasion of trophoblast cells via modulating mitochondrial function by Yu, Juan, Duan, Yaoyun, Lu, Qinsheng, Chen, Miaojuan, Ning, Fen, Ye, Yixin, Lu, Shenjiao, Ou, Deqiong, Sha, Xiaoyan, Gan, Xiaowen, Zhao, Mingguang, Lash, Gendie E.

“…Spontaneous miscarriage is a common complication of early pregnancy. Previous studies have shown that mitochondrial function plays an important role in…”
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Is there a place for Traditional Chinese Medicine (TCM) in the treatment of recurrent pregnancy loss? by Sun, Dingqian, Lu, Shenjiao, Gan, Xiaowen, Lash, Gendie E.

“…Recurrent pregnancy loss (RPL) impacts a couple’s quality of life, mental health and constitutes a large economic burden for care. Traditional Chinese Medicine…”
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