Search Results - "Lash, G E"

Interleukin-34 is present at the fetal-maternal interface and induces immunoregulatory macrophages of a decidual phenotype in vitro by Lindau, R, Mehta, R B, Lash, G E, Papapavlou, G, Boij, R, Berg, G, Jenmalm, M C, Ernerudh, J, Svensson-Arvelund, J

“…Abstract STUDY QUESTION Is the newly discovered cytokine interleukin (IL)-34 expressed at the human fetal-maternal interface in order to influence polarization…”
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Tumour cell dissemination following endoscopic stent insertion by Maruthachalam, K., Lash, G. E., Shenton, B. K., Horgan, A. F.

“…Background: This study examined whether colonoscopy or endoscopic stent insertion increases levels of carcinoembryonic antigen (CEA) and/or cytokeratin (CK) 20…”
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Effects of local decidua on trophoblast invasion and spiral artery remodeling in focal placenta creta – An immunohistochemical study by Hannon, T, Innes, B.A, Lash, G.E, Bulmer, J.N, Robson, S.C

“…Abstract Objectives Placenta creta is an increasingly prevalent cause of maternal morbidity/mortality. Decidua is at least focally defective and extravillous…”
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Localization of Angiogenic Growth Factors and Their Receptors in the Human Placental Bed Throughout Normal Human Pregnancy by Schiessl, B, Innes, B.A, Bulmer, J.N, Otun, H.A, Chadwick, T.J, Robson, S.C, Lash, G.E

“…Abstract During early human pregnancy invasion of uterine spiral arteries by extravillous trophoblast cells contributes to their remodelling characterised by…”
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Role of Interleukin 8 in Uterine Natural Killer Cell Regulation of Extravillous Trophoblast Cell Invasion by De Oliveira, L.G, Lash, G.E, Murray-Dunning, C, Bulmer, J.N, Innes, B.A, Searle, R.F, Sass, N, Robson, S.C

“…Abstract Background Extravillous trophoblast cell (EVT) invasion of maternal tissues is critical for successful pregnancy. Decidual factors, including uterine…”
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Triiodothyronine regulates angiogenic growth factor and cytokine secretion by isolated human decidual cells in a cell-type specific and gestational age-dependent manner by Vasilopoulou, E., Loubière, L.S., Lash, G.E., Ohizua, O., McCabe, C.J., Franklyn, J.A., Kilby, M.D., Chan, S.Y.

“…STUDY QUESTION Does triiodothyronine (T3) regulate the secretion of angiogenic growth factors and cytokines by human decidual cells isolated from early…”
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Secretion of Angiogenic Growth Factors by Villous Cytotrophoblast and Extravillous Trophoblast in Early Human Pregnancy by Lash, G.E, Naruse, K, Innes, B.A, Robson, S.C, Searle, R.F, Bulmer, J.N

“…Abstract Angiogenesis is a key feature of placental and uterine development in early pregnancy. We hypothesized that trophoblast cells produce angiogenic…”
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The Urokinase Plasminogen Activator (uPA) System in Uterine Natural Killer Cells in the Placental Bed During Early Pregnancy by Naruse, K, Lash, G.E, Bulmer, J.N, Innes, B.A, Otun, H.A, Searle, R.F, Robson, S.C

“…Abstract The urokinase plasminogen activator (uPA) system plays pivotal roles in cell invasion, adhesion and migration. Roles for uterine natural killer (uNK)…”
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Uterine spiral artery muscle dedifferentiation by Robson, A, Lash, G E, Innes, B A, Zhang, J Y, Robson, S C, Bulmer, J N

“…Abstract STUDY QUESTION Is vascular smooth muscle cell (VSMC) dedifferentiation a feature of uterine spiral artery (SpA) remodelling in early human pregnancy?…”
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Maternal plasma and amniotic fluid angiogenic factors and their receptors in monochorionic twin pregnancies complicated by twin‐to‐twin transfusion syndrome by Fox, C. E., Lash, G. E., Pretlove, S. J., Chan, B. C., Holder, R., Kilby, M. D.

“…Objective Angiogenic factors play a role in human placentation and may be aberrant in severe twin‐to‐twin transfusion syndrome (TTTS). The aim of this study…”
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Effect of Low Oxygen Concentrations on Trophoblast-Like Cell Line Invasion by Lash, G.E, Hornbuckle, J, Brunt, A, Kirkley, M, Searle, R.F, Robson, S.C, Bulmer, J.N

“…Abstract The applicability of trophoblast-like cell lines to the study of trophoblast function has been widely debated. The present study investigated the…”
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Altered decidual and placental catabolism of vitamin D may contribute to the aetiology of spontaneous miscarriage by Hou, H., Zhang, J.Y., Chen, D., Deng, F., Morse, A.N., Qiu, X., He, P., Lash, G.E.

“…Vitamin D catabolizing enzymes, along with vitamin D receptor (VDR) and vitamin D binding protein (DBP) are expressed in the decidua and placenta during…”
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Review: Functional role of uterine natural killer (uNK) cells in human early pregnancy decidua by Lash, G.E, Robson, S.C, Bulmer, J.N

“…Abstract Leukocytes comprise approximately 30–40% of decidual stromal cells in early human pregnancy. The major leukocyte component is the uterine natural…”
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Regulation of Trophoblast Invasion — A Workshop Report by Knöfler, M, Simmons, D.G, Lash, G.E, Harris, L.K, Armant, D.R

“…Abstract Trophoblast invasion during placental development helps to establish efficient physiological exchange between maternal and fetal circulatory systems…”
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Relationship between tissue damage and heme oxygenase expression in chorionic villi of term human placenta by Lash, G E, McLaughlin, B E, MacDonald-Goodfellow, S K, Smith, G N, Brien, J F, Marks, G S, Nakatsu, K, Graham, C H

“…Heme oxygenase (HO) catalyzes the oxidation of heme to carbon monoxide (CO), biliverdin, and iron and is thought to play a role in protecting tissues from…”
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Effects of hypoxia on heme oxygenase expression in human chorionic villi explants and immortalized trophoblast cells by Appleton, S D, Marks, G S, Nakatsu, K, Brien, J F, Smith, G N, Graham, C H, Lash, G E

“…Although hypoxia induces heme oxygenase (HO)-1 protein and mRNA expression in many cell types, hypoxia has also been shown to decrease HO-1 mRNA and protein…”
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Gestational Diseases — A Workshop Report by Lash, G.E, Quenby, S, Burton, G.J, Nakashima, A, Kamat, B.R, Ray, J, Bulmer, J.N

“…Abstract Between 11% and 20% of all clinically recognised pregnancies are lost before the 20th week of gestation, with huge financial and personal…”
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Regulation of extravillous trophoblast invasion by uterine natural killer cells is dependent on gestational age by Lash, Gendie E., Otun, Harry A., Innes, Barbara A., Percival, Kathryn, Searle, Roger F., Robson, Stephen C., Bulmer, Judith N.

“…BACKGROUND Extravillous trophoblast (EVT) cell invasion of uterine decidua and the inner third of myometrium is critical for successful pregnancy. Many…”
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Quantification of spiral artery remodelling using an Adobe Photoshop-based technique by Otun, H A, Innes, B A, Lash, G E, Schiessl, B, Ball, E, Searle, R F, Robson, S C, Bulmer, J N

“…Uterine spiral arteries undergo remodelling in normal pregnancy, with replacement of the musculoelastic arterial media by fibrinoid containing extravillous…”
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The Effects of Angiogenic Growth Factors on Extravillous Trophoblast Invasion and Motility by Lash, G.E, Cartwright, J.E, Whitley, G.St J, Trew, A.J, Baker, P.N

“…There is accumulating evidence that deficient trophoblast invasion of the placental bed spiral arteries is crucial to the pathogenesis of pre-eclampsia and…”
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