Search Results - "Lasarte, J J"

A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis by Ajona, Daniel, Ortiz-Espinosa, Sergio, Moreno, Haritz, Lozano, Teresa, Pajares, María J, Agorreta, Jackeline, Bértolo, Cristina, Lasarte, Juan J, Vicent, Silvestre, Hoehlig, Kai, Vater, Axel, Lecanda, Fernando, Montuenga, Luis M, Pio, Ruben

“…Disruption of the programmed cell death protein 1 (PD-1) pathway with immune checkpoint inhibitors represents a major breakthrough in the treatment of…”
Get more information

Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression by Corrales, Leticia, Ajona, Daniel, Rafail, Stavros, Lasarte, Juan J, Riezu-Boj, Jose I, Lambris, John D, Rouzaut, Ana, Pajares, Maria J, Montuenga, Luis M, Pio, Ruben

“…The complement system contributes to various immune and inflammatory diseases, including cancer. In this study, we investigated the capacity of lung cancer…”
Get full text

Poly(Anhydride) Nanoparticles Act as Active Th1 Adjuvants through Toll-Like Receptor Exploitation by Tamayo, I., Irache, J. M., Mansilla, C., Ochoa-Repáraz, J., Lasarte, J. J., Gamazo, C.

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

The involvement of ADAM10 in acantholysis in mucocutaneous pemphigus vulgaris depends on the autoantibody profile of each patient by Ivars, M., España, A., Alzuguren, P., Pelacho, B., Lasarte, J.J., López‐Zabalza, M.J.

“…Summary Background Acantholysis in pemphigus vulgaris (PV) may be triggered by desmoglein (Dsg) and non‐Dsg autoantibodies. The autoantibody profile of each…”
Get full text

Mutated trimeric RBD vaccines: a platform against variants of concern by Aparicio, Belén, Lasarte, Juan J., Sarobe, Pablo

Get full text

Poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as innate immune system activators by Camacho, A.I, Da Costa Martins, R, Tamayo, I, de Souza, J, Lasarte, J.J, Mansilla, C, Esparza, I, Irache, J.M, Gamazo, C

“…Abstract Adjuvant research is being oriented to TLR-agonists, but complement activation has been relatively unexplored. In previous studies it was demonstrated…”
Get full text

Enhanced cross-recognition of SARS-CoV-2 Omicron variant by peptide vaccine-induced antibodies by Aparicio, Belén, Ruiz, Marta, Casares, Noelia, Silva, Leyre, Egea, Josune, Pérez, Patricia, Albericio, Guillermo, Esteban, Mariano, García-Arriaza, Juan, Lasarte, Juan J, Sarobe, Pablo

“…Current vaccines against SARS-CoV-2, based on the original Wuhan sequence, induce antibodies with different degrees of cross-recognition of new viral variants…”
Get full text

Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer by Aparicio, Belén, Repáraz, David, Ruiz, Marta, Llopiz, Diana, Silva, Leyre, Vercher, Enric, Theunissen, Patrick, Tamayo, Ibon, Smerdou, Cristian, Igea, Ana, Santisteban, Marta, Gónzalez-Deza, Cristina, Lasarte, Juan J., Hervás-Stubbs, Sandra, Sarobe, Pablo

“…Immune checkpoint inhibitor (ICI)-based immunotherapy in triple negative breast cancer (TNBC) is achieving limited therapeutic results, requiring the…”
Get full text

Trial of complete weaning from immunosuppression for liver transplant recipients: Factors predictive of tolerance by Garza, Rocío García, Sarobe, Pablo, Merino, Juana, Lasarte, Juan J., D'Avola, Delia, Belsue, Virginia, Delgado, José A., Silva, Leyre, Iñarrairaegui, Mercedes, Sangro, Bruno, Sola, Jesus J., Pardo, Fernando, Quiroga, Jorge, Herrero, J. Ignacio

“…Recipients of liver transplantation (LT) may develop immunological tolerance. Factors predictive of tolerance are not clearly understood. Transplant recipients…”
Get full text

Erratum: Enhanced cross-recognition of SARS-CoV-2 Omicron variant by peptide vaccine-induced antibodies by Aparicio, Belén, Ruiz, Marta, Casares, Noelia, Silva, Leyre, Egea, Josune, Pérez, Patricia, Albericio, Guillermo, Esteban, Mariano, García-Arriaza, Juan, Lasarte, Juan J, Sarobe, Pablo

“…[This corrects the article DOI: 10.3389/fimmu.2022.1044025.]…”
Get full text

Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia by Calviño, Cristina, Ceballos, Candela, Alfonso, Ana, Jauregui, Patricia, Calleja-Cervantes, Maria E, San Martin-Uriz, Patxi, Rodriguez-Marquez, Paula, Martin-Mallo, Angel, Iglesias, Elena, Abizanda, Gloria, Rodriguez-Diaz, Saray, Martinez-Turrillas, Rebeca, Illarramendi, Jorge, Viguria, Maria C, Redondo, Margarita, Rifon, Jose, Villar, Sara, Lasarte, Juan J, Inoges, Susana, Lopez-Diaz de Cerio, Ascension, Hernaez, Mikel, Prosper, Felipe, Rodriguez-Madoz, Juan R

“…Despite the potential of CAR-T therapies for hematological malignancies, their efficacy in patients with relapse and refractory Acute Myeloid Leukemia has been…”
Get full text

Genetic Modification of CD8 + T Cells to Express EGFR: Potential Application for Adoptive T Cell Therapies by Lozano, Teresa, Chocarro, Silvia, Martin, Celia, Lasarte-Cia, Aritz, Del Valle, Cynthia, Gorraiz, Marta, Sarrión, Patricia, Ruiz de Galarreta, Marina, Lujambio, Amaia, Hervás-Stubbs, Sandra, Sarobe, Pablo, Casares, Noelia, Lasarte, Juan J

“…Adoptive immunotherapy with -expanded tumor-infiltrating lymphocytes (TILs) has achieved objective clinical responses in a significant number of patients with…”
Get full text

T- and B-cell responses to multivalent prime-boost DNA and viral vectored vaccine combinations against hepatitis C virus in non-human primates by Rollier, C S, Verschoor, E J, Verstrepen, B E, Drexhage, J A R, Paranhos-Baccala, G, Liljeström, P, Sutter, G, Arribillaga, L, Lasarte, J J, Bartosch, B, Cosset, F-L, Inchauspe, G, Heeney, J L

“…Immune responses against multiple epitopes are required for the prevention of hepatitis C virus (HCV) infection, and the progression to phase I trials of…”
Get full text

Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses by Aparicio, Belén, Casares, Noelia, Egea, Josune, Ruiz, Marta, Llopiz, Diana, Maestro, Sheila, Olagüe, Cristina, González-Aseguinolaza, Gloria, Smerdou, Cristian, López-Díaz de Cerio, Ascensión, Inogés, Susana, Prósper, Felipe, Yuste, José R., Carmona-Torre, Francisco, Reina, Gabriel, Lasarte, Juan J., Sarobe, Pablo

“…Identification of relevant epitopes is crucial for the development of subunit peptide vaccines inducing neutralizing and cellular immunity against SARS-CoV-2…”
Get full text

Skin lesion caused by ST398 and ST1 MRSA, Spain by Aspiroz, Carmen, Lozano, Carmen, Vindel, Ana, Lasarte, Juan J, Zarazaga, Myriam, Torres, Carmen

Get full text

CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination by Casares, Noelia, Arribillaga, Laura, Sarobe, Pablo, Dotor, Javier, Lopez-Diaz de Cerio, Ascensión, Melero, Ignacio, Prieto, Jesús, Borrás-Cuesta, Francisco, Lasarte, Juan J

“…CD25(+) regulatory T (T reg) cells suppress the activation/proliferation of other CD4(+) or CD8(+) T cells in vitro. Also, down-regulation of CD25(+) T reg…”
Get full text

Upregulation of Indoleamine 2,3-Dioxygenase in Hepatitis C Virus Infection by Larrea, Esther, Riezu-Boj, José I, Gil-Guerrero, Lucía, Casares, Noelia, Aldabe, Rafael, Sarobe, Pablo, Civeira, María P, Heeney, Jonathan L, Rollier, Christine, Verstrepen, Babs, Wakita, Takaji, Borrás-Cuesta, Francisco, Lasarte, Juan J, Prieto, Jesús

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Identification of CD4+ and CD8+ T cell epitopes of woodchuck hepatitis virus core and surface antigens in BALB/c mice by Ochoa-Callejero, L, Otano, I, Vales, A, Olagüe, C, Sarobe, P, Lasarte, J.J, Prieto, J, Menne, S, González-Aseguinolaza, G

“…Abstract A therapeutic vaccine against chronic hepatitis B virus (HBV) infection requires the development of a strong and multispecific Th1 cell immune…”
Get full text

Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model by Llopiz, Diana, Ruiz, Marta, Villanueva, Lorea, Iglesias, Tamara, Silva, Leyre, Egea, Josune, Lasarte, Juan J., Pivette, Perrine, Trochon-Joseph, Véronique, Vasseur, Bérangère, Dixon, Graham, Sangro, Bruno, Sarobe, Pablo

“…Immune checkpoint inhibitors are currently tested in different combinations in patients with advanced hepatocellular carcinoma (HCC). Nivolumab, an anti-PD-1…”
Get full text

Identification of peptide inhibitors of transforming growth factor beta 1 using a phage-displayed peptide library by Dotor, Javier, López-Vázquez, Ana B., Lasarte, Juan J., Sarobe, Pablo, García-Granero, Marta, Riezu-Boj, José I., Martínez, Alfonso, Feijoó, Esperanza, López-Sagaseta, Jacinto, Hermida, José, Prieto, Jesús, Borrás-Cuesta, Francisco

“…Pathologies such as liver fibrosis and scleroderma are characterized by harmful levels of transforming growth factor beta 1 (TGFβ1). These levels could be…”
Get full text