Search Results - "Lasance, Kathleen"

Modeling pulmonary alveolar microlithiasis by epithelial deletion of the Npt2b sodium phosphate cotransporter reveals putative biomarkers and strategies for treatment by Saito, Atsushi, Nikolaidis, Nikolaos M, Amlal, Hassane, Uehara, Yasuaki, Gardner, Jason C, LaSance, Kathleen, Pitstick, Lori B, Bridges, James P, Wikenheiser-Brokamp, Kathryn A, McGraw, Dennis W, Woods, Jason C, Sabbagh, Yves, Schiavi, Susan C, Altinişik, Göksel, Jakopović, Marko, Inoue, Yoshikazu, McCormack, Francis X

“…Pulmonary alveolar microlithiasis (PAM) is a rare, autosomal recessive lung disorder associated with progressive accumulation of calcium phosphate microliths…”
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mTOR Kinase Inhibition Effectively Decreases Progression of a Subset of Neuroendocrine Tumors that Progress on Rapalog Therapy and Delays Cardiac Impairment by Orr-Asman, Melissa A, Chu, Zhengtao, Jiang, Min, Worley, Mariah, LaSance, Kathleen, Koch, Sheryl E, Carreira, Vinicius S, Dahche, Hanan M, Plas, David R, Komurov, Kakajan, Qi, Xiaoyang, Mercer, Carol A, Anthony, Lowell B, Rubinstein, Jack, Thomas, Hala E

“…Inhibition of mTOR signaling using the rapalog everolimus is an FDA-approved targeted therapy for patients with lung and gastroenteropancreatic neuroendocrine…”
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Molecular strategy to reduce in vivo collagen barrier promotes entry of NCX1 positive inducible pluripotent stem cells (iPSC(NCX¹⁺)) into ischemic (or injured) myocardium by Huang, Wei, Dai, Bo, Wen, Zhili, Millard, Ronald W, Yu, Xi-Yong, Luther, Kristin, Xu, Meifeng, Zhao, Ting C, Yang, Huang-Tian, Qi, Zhihua, Lasance, Kathleen, Ashraf, Muhammad, Wang, Yigang

“…The purpose of this study was to assess the effect of collagen composition on engraftment of progenitor cells within infarcted myocardium. We previously…”
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Expression and therapeutic targeting of dopamine receptor-1 (D1R) in breast cancer by Borcherding, D C, Tong, W, Hugo, E R, Barnard, D F, Fox, S, LaSance, K, Shaughnessy, E, Ben-Jonathan, N

“…Patients with advanced breast cancer often fail to respond to treatment, creating a need to develop novel biomarkers and effective therapeutics. Dopamine (DA)…”
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Ocular Delivery of pRNA Nanoparticles: Distribution and Clearance After Subconjunctival Injection by Feng, Liang, Li, S. Kevin, Liu, Hongshan, Liu, Chia-Yang, LaSance, Kathleen, Haque, Farzin, Shu, Dan, Guo, Peixuan

“…ABSTRACT Purpose RNA nanoparticles derived from the three-way junction (3WJ) of the pRNA of bacteriophage phi29 DNA packaging motor were previously found to be…”
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Limb functional recovery is impaired in fibroblast growth factor-2 deficient (FGF2) mice despite chronic ischemia-induced vascular growth by Adeyemo, Adeola, Johnson, Christopher, Stiene, Andrew, LaSance, Kathleen, Qi, Zhihua, Lemen, Lisa, Schultz, Jo El J.

“…FGF2 is a potent stimulator of vascular growth; however, even with a deficiency of FGF2 ( Fgf2 −/−), developmental vessel growth or ischemia-induced…”
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Limb functional recovery is impaired in fibroblast growth factor-2 (FGF2) deficient mice despite chronic ischaemia-induced vascular growth by Adeyemo, Adeola, Johnson, Christopher, Stiene, Andrew, LaSance, Kathleen, Qi, Zhihua, Lemen, Lisa, Schultz, Jo El J.

“…FGF2 is a potent stimulator of vascular growth; however, even with a deficiency of FGF2 (Fgf2-/-), developmental vessel growth or ischaemia-induced…”
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Combining micro-computed tomography with histology to analyze biomedical implants for peripheral nerve repair by Hopkins, Tracy M., Heilman, Alexander M., Liggett, James A., LaSance, Kathleen, Little, Kevin J., Hom, David B., Minteer, Danielle M., Marra, Kacey G., Pixley, Sarah K.

“…•Imaged ex vivo iodinated normal and repaired nerves with micro-CT.•Removed iodine with sodium thiosulfate, allowing subsequent histology.•Removal of iodine…”
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EXTH-56. AROMATASE EXPRESSION IN HIGH GRADE GLIOMAS: A POTENTIAL NEW TARGET FOR THERAPY by Dave, Nimita, Sengaonkar, Vidula, Chow, Lionel M.L., Kendler, Ady, LaSance, Kathleen, Desai, Pankaj

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The role of proximal versus distal stomach resection in the weight loss seen after vertical sleeve gastrectomy by Kulkarni, Bhushan V, LaSance, Kathleen, Sorrell, Joyce E, Lemen, Lisa, Woods, Stephen C, Seeley, Randy J, Sandoval, Darleen

“…The mechanisms involved in the weight loss seen after vertical sleeve gastrectomy (VSG) are not clear. The rat stomach has two morphologically and functionally…”
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Preclinical pharmacological evaluation of letrozole as a novel treatment for gliomas by Dave, Nimita, Chow, Lionel M L, Gudelsky, Gary A, LaSance, Kathleen, Qi, Xiaoyang, Desai, Pankaj B

“…We present data that letrozole, an extensively used aromatase inhibitor in the treatment of estrogen receptor-positive breast tumors in postmenopausal women,…”
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Abstract 4241: Preclinical studies of brain/brain tumor disposition and antitumor efficacy of the aromatase inhibitor letrozole by Dave, Nimita, Desai, Pankaj B., Gudelsky, Gary A., LaSance, Kathleen, Chow, Lionel M.L., Qi, Xiaoyang

“…Abstract In this study, we investigated the potential role of aromatase (CYP19) as a target for the treatment of CNS malignancies, as well as brain disposition…”
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ATPS-13AROMATASE EXPRESSION IN HIGH GRADE GLIOMAS: A POTENTIAL NEW TARGET FOR THERAPY by Dave, Nimita, Sengaonkar, Vidula, Chow, Lionel M.L., Kendler, Ady, LaSance, Kathleen, Desai, Pankaj B.

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Optical and nuclear imaging of glioblastoma with phosphatidylserine-targeted nanovesicles by Blanco, Víctor M, Chu, Zhengtao, LaSance, Kathleen, Gray, Brian D, Pak, Koon Yan, Rider, Therese, Greis, Kenneth D, Qi, Xiaoyang

“…Multimodal tumor imaging with targeted nanoparticles potentially offers both enhanced specificity and sensitivity, leading to more precise cancer diagnosis and…”
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In vivo optical imaging of brain tumors and arthritis using fluorescent SapC-DOPS nanovesicles by Chu, Zhengtao, LaSance, Kathleen, Blanco, Victor, Kwon, Chang-Hyuk, Kaur, Balveen, Frederick, Malinda, Thornton, Sherry, Lemen, Lisa, Qi, Xiaoyang

“…We describe a multi-angle rotational optical imaging (MAROI) system for in vivo monitoring of physiopathological processes labeled with a fluorescent marker…”
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Molecular Strategy to Reduce In Vivo Collagen Barrier Promotes Entry of NCX1 Positive Inducible Pluripotent Stem Cells by Huang, Wei, Dai, Bo, Wen, Zhili, Millard, Ronald W, Yu, Xi-Yong, Luther, Kristin, Xu, Meifeng, Zhao, Ting C, Yang, Huang-Tian, Qi, Zhihua, LaSance, Kathleen, Ashraf, Muhammad, Wang, Yigang

“…Objective The purpose of this study was to assess the effect of collagen composition on engraftment of progenitor cells within infarcted myocardium. Background…”
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Molecular Strategy to Reduce In Vivo Collagen Barrier Promotes Entry of NCX1 Positive Inducible Pluripotent Stem Cells Myocardium by Huang, Wei, Dai, Bo, Wen, Zhili, Millard, Ronald W, Yu, Xi-Yong, Luther, Kristin, Xu, Meifeng, Zhao, Ting C, Yang, Huang-Tian, Qi, Zhihua, LaSance, Kathleen, Ashraf, Muhammad, Wang, Yigang

“…Objective The purpose of this study was to assess the effect of collagen composition on engraftment of progenitor cells within infarcted myocardium. Background…”
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In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles by Chu, Zhengtao, LaSance, Kathleen, Blanco, Victor, Kwon, Chang-Hyuk, Kaur, Balveen, Frederick, Malinda, Thornton, Sherry, Lemen, Lisa, Qi, Xiaoyang

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