Search Results - "Larsson, Susanna"
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Epidemiology of sarcopenia: Prevalence, risk factors, and consequences
Published in Metabolism, clinical and experimental (01-07-2023)“…Sarcopenia is a geriatric condition featured by a progressive loss of muscle mass and function and associated with various adverse health outcomes. In this…”
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Causal role of high body mass index in multiple chronic diseases: a systematic review and meta-analysis of Mendelian randomization studies
Published in BMC medicine (15-12-2021)“…Obesity is a worldwide epidemic that has been associated with a plurality of diseases in observational studies. The aim of this study was to summarize the…”
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An atlas on risk factors for type 2 diabetes: a wide-angled Mendelian randomisation study
Published in Diabetologia (01-11-2020)“…Aims/hypothesis The aim of this study was to use Mendelian randomisation (MR) to identify the causal risk factors for type 2 diabetes. Methods We first…”
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Smoking, alcohol consumption, and cancer: A mendelian randomisation study in UK Biobank and international genetic consortia participants
Published in PLoS medicine (23-07-2020)“…Smoking is a well-established cause of lung cancer and there is strong evidence that smoking also increases the risk of several other cancers. Alcohol…”
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Mendelian randomization as a tool for causal inference in human nutrition and metabolism
Published in Current opinion in lipidology (01-02-2021)“…The current review describes the fundamentals of the Mendelian randomization framework and its current application for causal inference in human nutrition and…”
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Coffee consumption and reduced risk of developing type 2 diabetes: a systematic review with meta-analysis
Published in Nutrition reviews (01-06-2018)“…Type 2 diabetes (T2D) is a major health problem worldwide that is associated with increased morbidity and mortality. There is increased interest in the value…”
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Mendelian randomization for cardiovascular diseases: principles and applications
Published in European heart journal (14-12-2023)“…Abstract Large-scale genome-wide association studies conducted over the last decade have uncovered numerous genetic variants associated with cardiometabolic…”
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Appraising the causal role of smoking in multiple diseases: A systematic review and meta-analysis of Mendelian randomization studies
Published in EBioMedicine (01-08-2022)“…The causal association between cigarette smoking and several diseases remains equivocal. The purpose of this study was to appraise the causal role of smoking…”
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Coffee and Caffeine Consumption and Risk of Kidney Stones: A Mendelian Randomization Study
Published in American journal of kidney diseases (01-01-2022)“…Coffee and caffeine consumption have been associated with a lower risk of kidney stones in observational studies. We conducted a Mendelian randomization study…”
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Body mass index and body composition in relation to 14 cardiovascular conditions in UK Biobank: a Mendelian randomization study
Published in European heart journal (07-01-2020)“…Abstract Aims The causal role of adiposity for several cardiovascular diseases (CVDs) is unclear. Our primary aim was to apply the Mendelian randomization…”
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Smoking and stroke: A mendelian randomization study
Published in Annals of neurology (01-09-2019)“…We used the Mendelian randomization design to explore the potential causal association of smoking with ischemic stroke and intracerebral hemorrhage using…”
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Association of Genetic Variants Related to Serum Calcium Levels With Coronary Artery Disease and Myocardial Infarction
Published in JAMA : the journal of the American Medical Association (25-07-2017)“…IMPORTANCE: Serum calcium has been associated with cardiovascular disease in observational studies and evidence from randomized clinical trials indicates that…”
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Adiposity, diabetes, lifestyle factors and risk of gastroesophageal reflux disease: a Mendelian randomization study
Published in European journal of epidemiology (01-07-2022)“…Adiposity, diabetes, and lifestyle factors are linked to gastroesophageal reflux disease (GERD) in observational studies. We conducted a two-sample Mendelian…”
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Alcohol Consumption and Risk of Atrial Fibrillation: A Prospective Study and Dose-Response Meta-Analysis
Published in Journal of the American College of Cardiology (22-07-2014)“…Although high alcohol consumption has been associated with increased risk of atrial fibrillation (AF), the role of light to moderate drinking remains unclear…”
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Does Treating Vascular Risk Factors Prevent Dementia and Alzheimer's Disease? A Systematic Review and Meta-Analysis
Published in Journal of Alzheimer's disease (01-01-2018)“…Epidemiological evidence has associated Alzheimer's disease (AD) with vascular risk factors (VRFs), but whether treatment of VRFs reduces the incidence of…”
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Coffee Consumption and Risk of Dementia and Alzheimer's Disease: A Dose-Response Meta-Analysis of Prospective Studies
Published in Nutrients (14-10-2018)“…Coffee consumption is associated with a reduced risk of several diseases but uncertainty remains about the influence of coffee consumption on the risk of…”
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Obesity and colon and rectal cancer risk: a meta-analysis of prospective studies
Published in The American journal of clinical nutrition (01-09-2007)“…BACKGROUND: Whereas obesity has been associated with an increased risk of colon cancer in men, a weak or no association has been observed in women. Results for…”
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Inverse Association Between Serum 25-Hydroxyvitamin D and Nonalcoholic Fatty Liver Disease
Published in Clinical gastroenterology and hepatology (01-02-2023)“…Serum 25-hydroxyvitamin D [S-25(OH)D] and nonalcoholic fatty liver disease (NAFLD) are correlated in many observational studies, whereas the causality of this…”
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Modifiable pathways in Alzheimer’s disease: Mendelian randomisation analysis
Published in BMJ (Online) (07-12-2017)“…AbstractObjectiveTo determine which potentially modifiable risk factors, including socioeconomic, lifestyle/dietary, cardiometabolic, and inflammatory factors,…”
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Dietary Approaches for Stroke Prevention
Published in Stroke (1970) (01-10-2017)“…Stroke is a leading cause of mortality and long-term disability. The consequences of stroke are often devastating and irreversible. Many stroke survivors…”
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