Search Results - "Larson, Peder E"
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Development of methods and feasibility of using hyperpolarized carbon‐13 imaging data for evaluating brain metabolism in patient studies
Published in Magnetic resonance in medicine (01-09-2018)“…Purpose Hyperpolarized carbon‐13 (13C) metabolic imaging is a noninvasive imaging modality for evaluating real‐time metabolism. The purpose of this study was…”
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Zero-Echo-Time and Dixon Deep Pseudo-CT (ZeDD CT): Direct Generation of Pseudo-CT Images for Pelvic PET/MRI Attenuation Correction Using Deep Convolutional Neural Networks with Multiparametric MRI
Published in Journal of Nuclear Medicine (01-05-2018)“…Accurate quantification of uptake on PET images depends on accurate attenuation correction in reconstruction. Current MR-based attenuation correction methods…”
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Calibrationless parallel imaging reconstruction based on structured low‐rank matrix completion
Published in Magnetic resonance in medicine (01-10-2014)“…Purpose A calibrationless parallel imaging reconstruction method, termed simultaneous autocalibrating and k‐space estimation (SAKE), is presented. It is a…”
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Translation of Carbon‐13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients
Published in Magnetic resonance in medicine (01-04-2019)“…Purpose To develop and translate a metabolite‐specific imaging sequence using a symmetric echo planar readout for clinical hyperpolarized (HP) Carbon‐13 (13C)…”
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5
Non-invasive assessment of telomere maintenance mechanisms in brain tumors
Published in Nature communications (04-01-2021)“…Telomere maintenance is a universal hallmark of cancer. Most tumors including low-grade oligodendrogliomas use telomerase reverse transcriptase (TERT)…”
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Iterative motion‐compensation reconstruction ultra‐short TE (iMoCo UTE) for high‐resolution free‐breathing pulmonary MRI
Published in Magnetic resonance in medicine (01-04-2020)“…Purpose To develop a high‐scanning efficiency, motion‐corrected imaging strategy for free‐breathing pulmonary MRI by combining an iterative motion‐compensation…”
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Extreme MRI: Large‐scale volumetric dynamic imaging from continuous non‐gated acquisitions
Published in Magnetic resonance in medicine (01-10-2020)“…Purpose To develop a framework to reconstruct large‐scale volumetric dynamic MRI from rapid continuous and non‐gated acquisitions, with applications to…”
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Regional quantification of cardiac metabolism with hyperpolarized [1-13C]-pyruvate CMR evaluated in an oral glucose challenge
Published in Journal of cardiovascular magnetic resonance (14-12-2023)“…The heart has metabolic flexibility, which is influenced by fed/fasting states, and pathologies such as myocardial ischemia and hypertrophic cardiomyopathy…”
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Ultrashort echo time and zero echo time MRI at 7T
Published in Magma (New York, N.Y.) (01-06-2016)“…Objective Zero echo time (ZTE) and ultrashort echo time (UTE) pulse sequences for MRI offer unique advantages of being able to detect signal from rapidly…”
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Motion robust high resolution 3D free‐breathing pulmonary MRI using dynamic 3D image self‐navigator
Published in Magnetic resonance in medicine (01-06-2018)“…Purpose To achieve motion robust high resolution 3D free‐breathing pulmonary MRI utilizing a novel dynamic 3D image navigator derived directly from imaging…”
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Hyperpolarized [1-13C] Glutamate: A Metabolic Imaging Biomarker of IDH1 Mutational Status in Glioma
Published in Cancer research (Chicago, Ill.) (15-08-2014)“…Mutations of the isocitrate dehydrogenase 1 (IDH1) gene are among the most prevalent in low-grade glioma and secondary glioblastoma, represent an early…”
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Assessment of lesion insertion tool in pelvis PET/MR data with applications to attenuation correction method development
Published in Journal of applied clinical medical physics (01-11-2024)“…Background In modern positron emission tomography (PET) with multi‐modality imaging (e.g., PET/CT and PET/MR), the attenuation correction (AC) is the single…”
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Assessing Prostate Cancer Aggressiveness with Hyperpolarized Dual-Agent 3D Dynamic Imaging of Metabolism and Perfusion
Published in Cancer research (Chicago, Ill.) (15-06-2017)“…New magnetic resonance (MR) molecular imaging techniques offer the potential for noninvasive, simultaneous quantification of metabolic and perfusion parameters…”
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Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2‐13C]dihydroxyacetone
Published in Magnetic resonance in medicine (01-01-2017)“…Purpose To investigate acute changes in glucose metabolism in liver and kidneys in vivo after a bolus injection of either fructose or glucose, using…”
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Data Format Standardization and DICOM Integration for Hyperpolarized 13C MRI
Published in Journal of digital imaging (01-10-2024)“…Hyperpolarized (HP) 13C MRI has shown promise as a valuable modality for in vivo measurements of metabolism and is currently in human trials at 15 research…”
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Atlas-Based Adaptive Hadamard-Encoded MR Spectroscopic Imaging at 3T
Published in Tomography (Ann Arbor) (23-08-2023)“…This study aimed to develop a time-efficient method of acquiring simultaneous, dual-slice MR spectroscopic imaging (MRSI) for the evaluation of brain…”
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Evaluation of Sinus/Edge-Corrected Zero-Echo-Time-Based Attenuation Correction in Brain PET/MRI
Published in Journal of Nuclear Medicine (01-11-2017)“…In brain PET/MRI, the major challenge of zero-echo-time (ZTE)-based attenuation correction (ZTAC) is the misclassification of air/tissue/bone mixtures or their…”
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Whole‐Abdomen Metabolic Imaging of Healthy Volunteers Using Hyperpolarized [1‐13C]pyruvate MRI
Published in Journal of magnetic resonance imaging (01-12-2022)“…Background Hyperpolarized 13C MRI quantitatively measures enzyme‐catalyzed metabolism in cancer and metabolic diseases. Whole‐abdomen imaging will permit…”
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Hyperpolarized [2-13C]-Fructose: A Hemiketal DNP Substrate for In Vivo Metabolic Imaging
Published in Journal of the American Chemical Society (09-12-2009)“…Hyperpolarized 13C labeled molecular probes have been used to investigate metabolic pathways of interest as well as facilitate in vivo spectroscopic imaging by…”
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Kinetic analysis of multi‐resolution hyperpolarized 13C human brain MRI to study cerebral metabolism
Published in Magnetic resonance in medicine (01-11-2022)“…Purpose To investigate multi‐resolution hyperpolarized (HP) 13C pyruvate MRI for measuring kinetic conversion rates in the human brain. Methods HP…”
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