Search Results - "Larson, Paul"

Deep Brain Stimulation for Movement Disorders by Larson, Paul S.

“…Deep brain stimulation (DBS) is an implanted electrical device that modulates specific targets in the brain resulting in symptomatic improvement in a…”
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Prefrontal-Subthalamic Hyperdirect Pathway Modulates Movement Inhibition in Humans by Chen, Witney, de Hemptinne, Coralie, Miller, Andrew M., Leibbrand, Michael, Little, Simon J., Lim, Daniel A., Larson, Paul S., Starr, Philip A.

“…The ability to dynamically change motor outputs, such as stopping an initiated response, is an important aspect of human behavior. A hyperdirect pathway…”
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Corruption, gender inequality and logistics performance by Larson, Paul D

“…PurposeThe purpose of this paper is to develop and test theory-driven hypotheses on the influence of corruption and gender inequality on logistics…”
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Process improvement in humanitarian operations: an organisational theory perspective by Larson, Paul D., Foropon, Cyril

“…Contingency theory suggests the best way to organise and lead an organisation, or to make decisions, depends upon internal and external situational factors,…”
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Consumer attitudes about electric cars: Pricing analysis and policy implications by Larson, Paul D, Viafara, Jairo, Parsons, Robert V, Elias, Arne

“…As electric vehicles (EVs) become more readily available, sales will depend on consumers' interest and understanding. A survey of consumer attitudes on…”
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Magnetic resonance imaging–guided phase 1 trial of putaminal AADC gene therapy for Parkinson's disease by Christine, Chadwick W., Bankiewicz, Krystof S., Van Laar, Amber D., Richardson, R. Mark, Ravina, Bernard, Kells, Adrian P., Boot, Brendon, Martin, Alastair J., Nutt, John, Thompson, Marin E., Larson, Paul S.

“…Objective To understand the safety, putaminal coverage, and enzyme expression of adeno‐associated viral vector serotype‐2 encoding the complementary DNA for…”
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Long-term wireless streaming of neural recordings for circuit discovery and adaptive stimulation in individuals with Parkinson’s disease by Gilron, Ro’ee, Little, Simon, Perrone, Randy, Wilt, Robert, de Hemptinne, Coralie, Yaroshinsky, Maria S., Racine, Caroline A., Wang, Sarah S., Ostrem, Jill L., Larson, Paul S., Wang, Doris D., Galifianakis, Nick B., Bledsoe, Ian O., San Luciano, Marta, Dawes, Heather E., Worrell, Gregory A., Kremen, Vaclav, Borton, David A., Denison, Timothy, Starr, Philip A.

“…Neural recordings using invasive devices in humans can elucidate the circuits underlying brain disorders, but have so far been limited to short recordings from…”
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An unexpectedly high rate of revisions and removals in deep brain stimulation surgery: Analysis of multiple databases by Rolston, John D, Englot, Dario J, Starr, Philip A, Larson, Paul S

“…Abstract Introduction Deep brain stimulation (DBS) is an established therapy for movement disorders, and is under active investigation for other neurologic and…”
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Security, sustainability and supply chain collaboration in the humanitarian space by Larson, Paul D

“…PurposeTo extend humanitarian supply chain relationships beyond logistics concerns of delivery, quality and cost. As humanitarian actors continue to face…”
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Life in a Time of Plague and Beyond by Larson, Paul C.

“…Plagues have come and gone throughout the course of human history. They can be extremely disruptive of societies through which they ravage and usually…”
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Improved Delivery Methods for Gene Therapy and Cell Transplantation in Parkinson's Disease by Larson, Paul S

“…A number of cell transplantation and gene therapy trials have been performed over the last three decades in an effort to restore function in Parkinson's…”
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A New Method and Mass Spectrometer Design for TOF-SIMS Parallel Imaging MS/MS by Fisher, Gregory L, Bruinen, Anne L, Ogrinc Potočnik, Nina, Hammond, John S, Bryan, Scott R, Larson, Paul E, Heeren, Ron M.A

“…We report a method for the unambiguous identification of molecules in biological and materials specimens at high practical lateral resolution using a new…”
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Gene therapy for aromatic L-amino acid decarboxylase deficiency by MR-guided direct delivery of AAV2-AADC to midbrain dopaminergic neurons by Pearson, Toni S., Gupta, Nalin, San Sebastian, Waldy, Imamura-Ching, Jill, Viehoever, Amy, Grijalvo-Perez, Ana, Fay, Alex J., Seth, Neha, Lundy, Shannon M., Seo, Youngho, Pampaloni, Miguel, Hyland, Keith, Smith, Erin, de Oliveira Barbosa, Gardenia, Heathcock, Jill C., Minnema, Amy, Lonser, Russell, Elder, J. Bradley, Leonard, Jeffrey, Larson, Paul, Bankiewicz, Krystof S.

“…Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare genetic disorder characterized by deficient synthesis of dopamine and serotonin. It presents in…”
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ACR guidance document on MR safe practices: 2013 by Kanal, Emanuel, Barkovich, A. James, Bell, Charlotte, Borgstede, James P., Bradley Jr, William G., Froelich, Jerry W., Gimbel, J. Rod, Gosbee, John W., Kuhni-Kaminski, Ellisa, Larson, Paul A., Lester Jr, James W., Nyenhuis, John, Schaefer, Daniel Joe, Sebek, Elizabeth A., Weinreb, Jeffrey, Wilkoff, Bruce L., Woods, Terry O., Lucey, Leonard, Hernandez, Dina

“…Because there are many potential risks in the MR environment and reports of adverse incidents involving patients, equipment and personnel, the need for a…”
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Clinical outcomes using ClearPoint interventional MRI for deep brain stimulation lead placement in Parkinson's disease by Ostrem, Jill L, Ziman, Nathan, Galifianakis, Nicholas B, Starr, Philip A, Luciano, Marta San, Katz, Maya, Racine, Caroline A, Martin, Alastair J, Markun, Leslie C, Larson, Paul S

“…The ClearPoint real-time interventional MRI-guided methodology for deep brain stimulation (DBS) lead placement may offer advantages to frame-based approaches…”
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Procedure‐Related Complications in Sham Surgeries for Parkinson's Clinical Trials: A Meta‐analysis by Mamaril‐Davis, James C., Gelb, Adrian W., Larson, Paul S.

“…Background Double‐blind, sham‐controlled neurosurgical trials for neurodegenerative disorders are debated as an ethical dilemma, particularly regarding…”
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Accounting for Deformation in Deep Brain Stimulation Surgery With Models: Comparison to Interventional Magnetic Resonance Imaging by Luo, Ma, Larson, Paul S., Martin, Alastair J., Miga, Michael I.

“…The efficacy of deep brain stimulation (DBS) depends on electrode placement accuracy, which can be jeopardized by brain shift due to burr hole and dura opening…”
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Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial by Marks, William J, MD, Ostrem, Jill L, MD, Verhagen, Leonard, MD, Starr, Philip A, MD, Larson, Paul S, MD, Bakay, Roy AE, MD, Taylor, Robin, MSN, Cahn-Weiner, Deborah A, PhD, Stoessl, A Jon, MD, Olanow, C Warren, MD, Bartus, Raymond T, PhD

“…Summary Background There is an urgent need for therapies that slow or reverse the progression of Parkinson's disease (PD). Neurotrophic factors can improve the…”
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Phylogenetic analysis reveals an evolutionary transition from internal to external brooding in Epiactis Verrill (Cnidaria: Anthozoa: Actiniaria) and rejects the validity of the genus Cnidopus Carlgren by Larson, Paul G., Daly, Marymegan

“…[Display omitted] •Epiactis is a polyphyletic group, but Epiactis sensu stricto is monophyletic.•Cnidopus is not a valid genus.•External brooders have evolved…”
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Safety of AADC Gene Therapy for Moderately Advanced Parkinson Disease: Three-Year Outcomes From the PD-1101 Trial by Christine, Chadwick W., Richardson, R. Mark, Van Laar, Amber D., Thompson, Marin E., Fine, Elisabeth M., Khwaja, Omar S., Li, Chunming, Liang, Grace S., Meier, Andreas, Roberts, Eiry W., Pfau, Madeline L., Rodman, Josh R., Bankiewicz, Krystof S., Larson, Paul S.

“…To report final, 36-month safety and clinical outcomes from the PD-1101 trial of NBIb-1817 (VY-AADC01) in participants with moderately advanced Parkinson…”
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