Search Results - "Larson, Pamela S"
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Allele Imbalance, or Loss of Heterozygosity, in Normal Breast Epithelium of Sporadic Breast Cancer Cases and BRCA1 Gene Mutation Carriers Is Increased Compared With Reduction Mammoplasty Tissues
Published in Journal of clinical oncology (01-12-2005)“…Normal-appearing breast epithelium can contain genetic abnormalities, including allele imbalance (AI), also referred to as loss of heterozygosity. Whether…”
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Quantitative DNA Fingerprinting May Distinguish New Primary Breast Cancer From Disease Recurrence
Published in Journal of clinical oncology (15-05-2004)“…Approximately 10% of women with breast cancer develop a second breast tumor, either a new primary or a recurrence. Differentiating between these entities using…”
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3
Loss of Heterozygosity or Allele Imbalance in Histologically Normal Breast Epithelium Is Distinct from Loss of Heterozygosity or Allele Imbalance in Co-Existing Carcinomas
Published in The American journal of pathology (01-07-2002)“…To better understand early steps in human breast carcinogenesis, we examined allele imbalance or loss of heterozygosity (LOH), in co-existing normal-appearing…”
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In utero exposure to diethylstilbestrol (DES) does not increase genomic instability in normal or neoplastic breast epithelium
Published in Cancer (01-11-2006)“…BACKGROUND. In 1992, the National Cancer Institute (NCI) established the Continuation of Follow‐Up of DES‐Exposed Cohorts to study the long‐term health effects…”
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Genetically abnormal clones in histologically normal breast tissue
Published in The American journal of pathology (01-06-1998)“…Breast cancer is believed to develop as multiple genetic abnormalities accumulate, each conferring some growth advantage, but the timing and nature of the…”
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CDKN1C/p57kip2 is a candidate tumor suppressor gene in human breast cancer
Published in BMC cancer (06-03-2008)“…CDKN1C (also known as p57KIP2) is a cyclin-dependent kinase inhibitor previously implicated in several types of human cancer. Its family members…”
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Loss of heterozygosity in serial plasma DNA samples during follow‐up of women with breast cancer
Published in International journal of cancer (10-10-2003)“…We evaluated the potential utility of occult circulating tumor DNA as a molecular marker of disease in subjects previously diagnosed with breast cancer. Using…”
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Microsatellite alterations indicating monoclonality in atypical hyperplasias associated with breast cancer
Published in Human pathology (01-02-1997)“…One model of breast tumorigenesis postulates a sequential evolution from normal to proliferative epithelium and eventually to neoplasia, but genetic data to…”
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CDKN1C/p57kip2is a candidate tumor suppressor gene in human breast cancer
Published in BMC cancer (06-03-2008)“…Abstract Background CDKN1C (also known as p57 KIP2 ) is a cyclin-dependent kinase inhibitor previously implicated in several types of human cancer. Its family…”
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CDKN1C /p57.sup.kip2 .sup.is a candidate tumor suppressor gene in human breast cancer
Published in BMC cancer (06-03-2008)Get full text
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DNA alterations in tumor scrapesvs. biopsies of squamous-cell carcinomas of the head and neck
Published in International journal of cancer (20-03-2000)Get full text
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CDKN1C/p57 super(kip2 )is a candidate tumor suppressor gene in human breast cancer
Published in BMC cancer (01-01-2008)“…Background CDKN1C (also known as p57 super(KIP2)) is a cyclin-dependent kinase inhibitor previously implicated in several types of human cancer. Its family…”
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Loss of heterozygosity at 11q23 in squamous cell carcinoma of the head and neck is associated with recurrent disease
Published in Clinical cancer research (01-11-1998)“…Loss of heterozygosity (LOH) at chromosome 11q23 has been found in a variety of epithelial human neoplasms, suggesting that this region contains a tumor…”
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14
Detection of monoclonal microsatellite alterations in atypical breast hyperplasia
Published in The Journal of clinical investigation (01-09-1996)“…Atypical hyperplastic (AH) breast lesions are currently classified and treated as benign proliferative disorders, but their presence is associated with a four-…”
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15
DNA alterations in tumor scrapes vs. biopsies of squamous‐cell carcinomas of the head and neck
Published in International journal of cancer (20-03-2000)“…Genetic abnormalities in SCCHNs are frequent and may be useful for screening, follow‐up and prognosis. A biopsy or resection generally is utilized to identify…”
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Lack of correlation between morphometric analysis and presence of microsatellite alterations in proliferative ductal lesions of the breast
Published in Analytical and quantitative cytology and histology (01-10-1999)“…To apply morphometric studies using an image analyzer to a previously reported group of proliferative duct lesions and to compare results to see if there was a…”
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