Search Results - "Larsen, Niels B"

Single-molecule denaturation mapping of DNA in nanofluidic channels by Reisner, Walter, Larsen, Niels B., Silahtaroglu, Asli, Kristensen, Anders, Tommerup, Niels, Tegenfeldt, Jonas O., Flyvbjerg, Henrik, Austin, Robert H.

“…Here we explore the potential power of denaturation mapping as a single-molecule technique. By partially denaturing YOYO®-1-labeled DNA in nanofluidic channels…”
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Injection molded nanofluidic chips: fabrication method and functional tests using single-molecule DNA experiments by Utko, Pawel, Persson, Fredrik, Kristensen, Anders, Larsen, Niels B

“…We demonstrate that fabrication of well-defined nanofluidic systems can be greatly simplified by injection molding of thermoplastic polymers. Chips featuring…”
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Immobilization of Active Antibodies at Polymer Melt Surfaces during Injection Molding by Hobæk, Thor Christian, Pranov, Henrik J, Larsen, Niels B

“…We demonstrate the transfer and immobilization of active antibodies from a low surface- energy mold surface to thermoplastic replica surfaces using injection…”
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Light-Induced Local Heating for Thermophoretic Manipulation of DNA in Polymer Micro- and Nanochannels by Thamdrup, Lasse H, Larsen, Niels B, Kristensen, Anders

“…We present a method for making polymer chips with a narrow-band near-infrared absorber layer that enables light-induced local heating of liquids inside fluidic…”
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Conductive Polymer Functionalization by Click Chemistry by Daugaard, Anders Egede, Hvilsted, Søren, Hansen, Thomas Steen, Larsen, Niels B

“…Click chemistry is used to obtain new conductive polymer films based on poly(3,4-ethylenedioxythiophene) (PEDOT) from a new azide functional monomer…”
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Embedded 3D Printing in Self‐Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs by Kajtez, Janko, Wesseler, Milan Finn, Birtele, Marcella, Khorasgani, Farinaz Riyahi, Rylander Ottosson, Daniella, Heiskanen, Arto, Kamperman, Tom, Leijten, Jeroen, Martínez‐Serrano, Alberto, Larsen, Niels B., Angelini, Thomas E., Parmar, Malin, Lind, Johan U., Emnéus, Jenny

“…Human in vitro models of neural tissue with tunable microenvironment and defined spatial arrangement are needed to facilitate studies of brain development and…”
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Nanoconfinement-enhanced conformational response of single DNA molecules to changes in ionic environment by Reisner, Walter, Beech, Jason P, Larsen, Niels B, Flyvbjerg, Henrik, Kristensen, Anders, Tegenfeldt, Jonas O

“…We show that the ionic environment plays a critical role in determining the configurational properties of DNA confined in silica nanochannels. The extension of…”
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In-chip fabrication of free-form 3D constructs for directed cell migration analysis by Olsen, Mark Holm, Hjortø, Gertrud Malene, Hansen, Morten, Met, Özcan, Svane, Inge Marie, Larsen, Niels B

“…Free-form constructs with three-dimensional (3D) microporosity were fabricated by two-photon polymerization inside the closed microchannel of an…”
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Stereolithographic hydrogel printing of 3D culture chips with biofunctionalized complex 3D perfusion networks by Zhang, Rujing, Larsen, Niels B

“…Three-dimensional (3D) in vitro models capturing both the structural and dynamic complexity of the in vivo situation are in great demand as an alternative to…”
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Spatially Selective Functionalization of Conducting Polymers by "Electroclick" Chemistry by Hansen, Thomas Steen, Daugaard, Anders Egede, Hvilsted, Søren, Larsen, Niels B.

“…Conducting polymer microelectrodes can electrochemically generate the catalyst required for their own functionalization by “click chemistry” with high spatial…”
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Directed self-organization of single DNA molecules in a nanoslit via embedded nanopit arrays by Reisner, Walter, Larsen, Niels B, Flyvbjerg, Henrik, Tegenfeldt, Jonas O, Kristensen, Anders

“…We show that arrays of nanopit structures etched in a nanoslit can control the positioning and conformation of single DNA molecules in nanofluidic devices. By…”
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Silk scaffolding drives self-assembly of functional and mature human brain organoids by Sozzi, Edoardo, Kajtez, Janko, Bruzelius, Andreas, Wesseler, Milan Finn, Nilsson, Fredrik, Birtele, Marcella, Larsen, Niels B., Ottosson, Daniella Rylander, Storm, Petter, Parmar, Malin, Fiorenzano, Alessandro

“…Human pluripotent stem cells (hPSCs) are intrinsically able to self-organize into cerebral organoids that mimic features of developing human brain tissue…”
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Characterization of Ultrathin Poly(ethylene glycol) Monolayers on Silicon Substrates by Papra, Alexander, Gadegaard, Nikolaj, Larsen, Niels B

“…Low molecular weight poly(ethylene glycol) silanes (PEG silanes) have been grafted onto the surface of silicon wafers in a one-step procedure yielding…”
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Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons by Vasudevan, Shashank, Kajtez, Janko, Bunea, Ada‐Ioana, Gonzalez‐Ramos, Ana, Ramos‐Moreno, Tania, Heiskanen, Arto, Kokaia, Merab, Larsen, Niels B., Martínez‐Serrano, Alberto, Keller, Stephan S., Emnéus, Jenny

“…In Parkinson's disease, the degeneration of dopaminergic neurons in substantia nigra leads to a decrease in the physiological levels of dopamine in striatum…”
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Facile Photoimmobilization of Proteins onto Low-Binding PEG-Coated Polymer Surfaces by Larsen, Esben Kjær Unmack, Mikkelsen, Morten Bo Lindholm, Larsen, Niels B

“…Immobilization of proteins onto polymer surfaces usually requires specific reactive functional groups. Here, we show an easy one-step method to conjugate…”
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Protein and cell patterning in closed polymer channels by photoimmobilizing proteins on photografted poly(ethylene glycol) diacrylate by Larsen, Esben Kjær Unmack, Mikkelsen, Morten Bo Lindholm, Larsen, Niels B

“…Definable surface chemistry is essential for many applications of microfluidic polymer systems. However, small cross-section channels with a high surface to…”
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Effect of Solvents and Concentration on the Formation of a Self-Assembled Monolayer of Octadecylsiloxane on Silicon (001) by Rozlosnik, Noémi, Gerstenberg, Michael C, Larsen, Niels B

“…We have explored the effects of solvent, adsorber concentration, and environment on the formation of high-coverage monolayers of alkylsiloxanes on silicon…”
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Micro-drilling of polymer tubular ultramicroelectrode arrays for electrochemical sensors by Kafka, Jan, Skaarup, Steen, Geschke, Oliver, Larsen, Niels B

“…We present a reproducible fast prototyping procedure based on micro-drilling to produce homogeneous tubular ultramicroelectrode arrays made from…”
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Decoupled phase transitions and grain-boundary melting in supported phospholipid bilayers by KELLER, Danielle, LARSEN, Niels B, MILLER, Ian M, MOURITSEN, Ole G

“…Two separate liquid-solid phase transitions are detected in the two monolayers of a mica-supported phospholipid bilayer by atomic force microscopy. The phase…”
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Solvent Composition Directing Click-Functionalization at the Surface or in the Bulk of Azide-Modified PEDOT by Lind, Johan U, Hansen, Thomas S, Daugaard, Anders E, Hvilsted, Søren, Andresen, Thomas L, Larsen, Niels B

“…Thin films of the conducting polymer poly(3,4-(1-azidomethylethylene)dioxythiophene) tosylate (PEDOT−N3) can be functionalized by reaction with alkynated…”
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